Glioblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-06-29Clinical Trial Results: Tofacitinib in Recurrent GBM Patients [Phase 3]
Phase 3 trial results for tofacitinib in recurrent glioblastoma completed with results posted.
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CLINICAL_TRIALS trial_result · 2026-06-23Clinical Trial Update: Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated Glioblastoma [Phase 3]
Phase 3 trial update evaluating adding lomustine to standard temozolomide and radiation for newly diagnosed MGMT-methylated glioblastoma; st…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma [Phase 2, Phase 3]
A multi-regimen Phase 2/3 clinical trial in newly diagnosed and recurrent glioblastoma is currently recruiting. The study is sponsored by th…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM) [Phase 1]
A Phase 1 clinical trial evaluating RNA-lipid particle vaccines for newly diagnosed pediatric high-grade gliomas and adult glioblastoma is c…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: UNITy-BasED MR-Linac Adaptive Simultaneous Integrated Hypofractionated Boost Trial for High Grade Glioma in the Elderly [Phase 2]
This clinical trial update covers a Phase 2 study of Unity MR-Linac adaptive hypofractionated boost for high-grade glioma in elderly patient…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM [Phase 3]
Phase 3 trial evaluating Sonocloud-9 with Carboplatin versus standard chemotherapy (lomustine or temozolomide) for recurrent glioblastoma; r…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma [Phase 1, Phase 2]
A clinical trial update on LMP744, an indenoisoquinolone Topoisomerase I inhibitor, being studied for recurrent glioblastoma (including IDH-…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Dual-Targeting CAR-NK Cells for Recurrent/Progressive Glioblastoma and High-Grade Glioma [Phase 1]
A Phase 1 clinical trial evaluating dual-targeting CAR-NK cells for recurrent/progressive glioblastoma and high-grade gliomas is currently r…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Investigational Imaging Technique During Brain Surgery [NA]
A clinical trial evaluating an investigational imaging technique during brain tumor surgery has been suspended. The study involves astrocyto…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Locoregional Administration of Genetically Engineered Cells (EGFR/IL13Rα2 Pool-CAR T Cells) for the Treatment of Recurrent or Progressive High-Grade Gliomas [Phase 1]
This update describes a Phase 1 clinical trial evaluating locoregional administration of EGFR/IL13Rα2 Pool-CAR T cells for recurrent or prog…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: DOC1021 Dendritic Cell Immunotherapy for Treatment of Newly Diagnosed Adult Glioblastoma (GBM) [Phase 2]
Phase 2 clinical trial evaluating DOC1021 dendritic cell immunotherapy for newly diagnosed adult glioblastoma, currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: POSitron Emission Imaging Using 18F-FDOPA in Neurooncology [NA]
This clinical trial update reports on a study evaluating PET imaging with 18F-FDOPA for glioblastoma in neuro-oncology. The trial status is …
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Testing Cerebrospinal Fluid for Cell-free Tumor DNA in Children, Adolescents, and Young Adults With Brain Tumors
This trial update describes a pediatric brain tumor study using cerebrospinal fluid cell-free tumor DNA; the study was terminated.
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Trial of Anti-Tim-3 in Combination With Anti-PD-1 and SRS in Recurrent GBM [Phase 1]
Phase 1 clinical trial update for recurrent glioblastoma evaluating a TIM-3–targeting antibody in combination with PD-1 blockade and stereot…
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Efficacy of Zoster Vaccination in Glioblastoma Patients [Phase 4]
Phase 4 clinical trial evaluating the efficacy of zoster vaccination in patients with glioblastoma. The study is currently not yet recruitin…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Intracranial Injection of NK-92/5.28.z Cells in Combination With Intravenous Ezabenlimab in Patients With Recurrent HER2-positive Glioblastoma [Phase 1]
Phase 1 trial evaluating intracranial NK-92/5.28.z cell therapy in combination with intravenous ezabenlimab for recurrent HER2-positive glio…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant [Phase 2]
Phase 2 clinical trial exploring ribociclib with everolimus or with temozolomide for high-grade gliomas and related diffuse gliomas; recruit…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Autologous CAR-T Cells Targeting B7-H3 in Recurrent or Refractory GBM CAR.B7-H3Tc [Phase 1]
Phase 1 study of autologous CAR-T cells targeting B7-H3 (CAR.B7-H3Tc) for recurrent or refractory glioblastoma, currently recruiting.
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Preoperative Radiosurgery for the Treatment of High Grade Glioma, NeoGlioma Trial [Phase 1]
Phase 1 NeoGlioma trial evaluating preoperative radiosurgery for high-grade glioma is currently recruiting.
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CLINICAL_TRIALS withdrawal · 2026-04-21Clinical Trial Update: Anti-Lag-3 (Relatlimab) and Anti-PD-1 Blockade (Nivolumab) Versus Standard of Care (Lomustine) for the Treatment of Patients With Recurrent Glioblastoma [Phase 2]
A Phase 2 trial evaluating relatlimab (anti-LAG-3) plus nivolumab (anti-PD-1) versus lomustine for recurrent glioblastoma has been suspended…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Multicenter Trial to Identify Optimal Atezolizumab Biomarkers in the Setting of Recurrent Glioblastoma. The MOAB Trial [Phase 2]
A Phase 2 multicenter trial (MOAB) at Duke University is investigating optimal atezolizumab biomarkers in recurrent glioblastoma and is curr…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Study With L19TNF in Combination With Lomustine in Patients With Glioblastoma at Progression or Recurrence [Phase 2]
Phase 2 clinical trial update examining L19TNF in combination with lomustine for glioblastoma at progression or recurrence; study is current…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: ATM-Inhibitor WSD0628 in Combination With Radiation Therapy for Treatment of Recurrent High-Grade Glioma [Phase 1]
Phase 1 trial assessing WSD0628, an ATM inhibitor, in combination with radiation therapy for recurrent high-grade glioma (glioblastoma) is c…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Sitagliptin in Recurrent/Progressive Grade 4 Glioma [Phase 1]
Clinical trial update describing a Phase 1 study of sitagliptin in recurrent or progressive glioma and glioblastoma, with status NOT_YET_REC…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: Proof-of-Concept Study of ACT001 in Adult Patients With Recurrent Glioblastoma Harbouring STAT3-High Signature [Phase 2]
Phase 2 proof-of-concept study of ACT001 in adults with recurrent glioblastoma has been suspended.