Glioblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Combination ADI-PEG 20, TMZ, and RT for Treatment of Newly Diagnosed High-grade Glioma (HGG) [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating a combination of ADI-PEG 20, temozolomide, and radiotherapy for newly diagnosed high-grade glioma, …
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Pilot Study of a Metabolic Nutritional Therapy for the Management of Primary Brain Tumors [NA]
A pilot clinical trial at Michigan State University is evaluating a metabolic nutritional therapy for the management of glioblastoma, a prim…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: 5G-PEARL: Paxalisib in Malignant Brain Tumours [Phase 1, Phase 2]
This update describes a Phase 1/2 clinical trial (5G-PEARL) evaluating paxalisib in malignant brain tumors, currently recruiting.
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Pilot Study of Navigated Focused Ultrasound and Pembrolizumab in the Treatment of Recurrent WHO Grade 4 IDH-Wildtype Glioblastoma With Mismatch Repair Deficiency [Phase 1]
A Phase 1 pilot study evaluating the combination of navigated focused ultrasound and pembrolizumab for recurrent glioblastoma with mismatch …
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Improving Understanding of Glioblastoma Through Preservation of Biologically Active Brain Tissue
This entry provides an update on an ongoing clinical trial aimed at improving understanding of glioblastoma by preserving biologically activ…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: CARv3-TEAM-E T Cells in Glioblastoma [Phase 1]
A Phase 1 clinical trial evaluating CARv3-TEAM-E T cells for glioblastoma and malignant glioma is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Contribution From PET-DOPA in Glioblastoma Re-irradiation - A Randomized Phase II Study [Phase 2]
A randomized Phase II trial is evaluating the use of PET-DOPA imaging to guide re-irradiation in patients with glioblastoma and is currently…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Dose Finding Study of [177Lu]Lu-NeoB in Newly Diagnosed Glioblastoma and in Recurrent Glioblastoma [Phase 1]
Phase 1 dose-finding trial of [177Lu]Lu-NeoB in newly diagnosed and recurrent glioblastoma; study status is active but not recruiting.
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Surgery for Recurrent Glioblastoma [Phase 2]
A Phase 2 clinical trial assessing surgical treatment for recurrent glioblastoma is currently recruiting, sponsored by Insel Gruppe AG and U…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Limited Target Volume Radiotherapy After Glioblastoma Surgery [NA]
This clinical trial is studying limited target volume radiotherapy after glioblastoma surgery and is currently not yet recruiting.
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: ARISTOCRAT: Blinded Trial of Temozolomide +/- Cannabinoids [Phase 2]
ARISTOCRAT is a Phase 2 blinded trial evaluating temozolomide with or without cannabinoids in glioblastoma, currently recruiting.
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Venous Thromboembolism Prevention in Outpatients With Glioma [Phase 2]
A Phase 2 clinical trial is updating recruitment status for venous thromboembolism prevention in outpatients with glioma, including glioblas…
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: CAR T Cells in Patients With MMP2+ Recurrent or Progressive Glioblastoma [Phase 1]
A Phase 1 trial evaluating CAR T cells targeting MMP2 in patients with recurrent or progressive glioblastoma; the study is currently active …
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: GPC-3 CAR T CELLS FOR Recurrent GPC-3 Positive Glioblastoma [Phase 1]
Phase 1 clinical trial evaluating GPC-3–targeted CAR T cells in adults with recurrent GPC-3–positive glioblastoma.
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Prospective Cohort of Patients With Newly Diagnosed Glioblastoma: Analysis of MMP2 and MMP9 Expression and Correlation to Neuro-imaging Features. [NA]
This clinical trial update describes a prospective cohort study in patients with newly diagnosed glioblastoma examining MMP2 and MMP9 expres…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Intensity-Modulated Stereotactic Radiation Therapy in Treating Patients With Grade II-IV Glioma [NA]
Ongoing clinical trial evaluating intensity-modulated stereotactic radiotherapy for patients with grade II–IV gliomas, including glioblastom…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: A Study of BPM31510 With Vitamin K1 in Subjects With Newly Diagnosed Glioblastoma (GB) [Phase 2]
Phase 2 clinical trial evaluating BPM31510 with Vitamin K1 in newly diagnosed glioblastoma; the study is currently active but not recruiting…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Irinotecan-ChemoSeed in Surgically Resectable Glioblastoma [Phase 2]
A Phase 2 clinical trial update for Irinotecan-ChemoSeed in surgically resectable glioblastoma; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: MRinRT: Swansea University and SWWCC Collaboration Study.
The MRinRT Swansea University and SWWCC collaboration study updates on MRI-guided adaptive radiotherapy and is not yet recruiting, with mult…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: LITT Followed by Hypofractionated RT for Recurrent Gliomas [NA]
Clinical trial evaluating laser interstitial thermal therapy (LITT) followed by hypofractionated radiation therapy for recurrent gliomas; re…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Effect of Salovum® on Pressure, Oxygen and Inflammation in Glioblastoma [Phase 2]
A Phase 2 clinical trial is evaluating Salovum for effects on brain pressure, oxygenation, and inflammation in glioblastoma, currently recru…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Phase I CB-NK-TGF-ßR2-/NR3C1- in rGBM [Phase 1]
A Phase I clinical trial update for CB-NK-TGF-ßR2-/NR3C1- therapy in recurrent gliosarcoma and recurrent supratentorial glioblastoma, curren…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: A Study to Evaluate the Safety of a Stem Cell-Based Gene and Cell Therapy in Patients With Newly Diagnosed Glioblastoma [Phase 1]
This document describes a phase 1 clinical trial to evaluate the safety of a stem cell-based gene and cell therapy in patients with newly di…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Study of Pembrolizumab and M032 (NSC 733972) [Phase 1, Phase 2]
A Phase 1/2 clinical trial update evaluating pembrolizumab in combination with M032 for glioblastoma, anaplastic astrocytoma, and gliosarcom…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: 5G-RUBY: Avutometinib and Defactinib in Malignant Brain Tumours [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the combination of Avutometinib and Defactinib in malignant brain tumors is currently recruiting.