Geographic Atrophy
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CLINICAL_TRIALS trial_result · 2019-02-21Clinical Trial Update: An Extension Study to Evaluate the Long-Term Safety of Lampalizumab in Participants With Geographic Atrophy [Phase 2]
An extension study to evaluate long-term safety of lampalizumab in geographic atrophy participants; terminated with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-02-19Clinical Trial Update: A Study of Lampalizumab Intravitreal Injections Administered Every Two Weeks or Every Four Weeks to Participants With Geographic Atrophy [Phase 2]
Phase 2 trial evaluating intravitreal lampalizumab every two or four weeks in geographic atrophy completed with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Long-Term Safety of Lampalizumab Intravitreal (ITV) Injections in Participants With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (OMASPECT) [Phase 3]
Phase 3 trial update on long-term safety of lampalizumab intravitreal injections in geographic atrophy due to age-related macular degenerati…
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CLINICAL_TRIALS trial_result · 2018-12-19Clinical Trial Update: CLG561 Proof-of-Concept Study as a Monotherapy and in Combination With LFG316 in Subjects With Geographic Atrophy (GA) [Phase 2]
Phase 2 clinical trial update for CLG561 as monotherapy and in combination with LFG316 in Geographic Atrophy; study completed with results p…
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CLINICAL_TRIALS trial_result · 2018-07-27Clinical Trial Update: Intravitreal LFG316 in Patients With Age-related Macular Degeneration (AMD) [Phase 2]
Phase 2 trial of intravitreal LFG316 in geographic atrophy and age-related macular degeneration has completed; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Safety and Efficacy Assessment Treatment Trials of Emixustat Hydrochloride [Phase 2, Phase 3]
Phase 2 and Phase 3 trials evaluating emixustat hydrochloride for geographic atrophy have completed, with safety and efficacy assessed.
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CLINICAL_TRIALS trial_result · 2017-05-08Clinical Trial Update: Sparing of the Fovea in Geographic Atrophy Progression
Clinical trial update on strategies to spare the fovea during geographic atrophy progression. The study involves conditions including geogra…
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CLINICAL_TRIALS trial_result · 2017-05-05Clinical Trial Update: Clinical Study to Investigate Safety and Efficacy of GSK933776 in Adult Patients With Geographic Atrophy Secondary to Age-related Macular Degeneration [Phase 2]
Phase 2 clinical trial evaluating the safety and efficacy of GSK933776 in adults with geographic atrophy due to age-related macular degenera…
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: A Study of Safety, Tolerability, and Evidence of Activity of FCFD4514S Administered Monthly or Every Other Month to Patients With Geographic Atrophy [Phase 2]
A Phase 2 study evaluating safety, tolerability, and evidence of activity of the investigational drug FCFD4514S in geographic atrophy has be…
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CLINICAL_TRIALS trial_result · 2016-06-02Clinical Trial Update: Long-Term Follow-up Safety Study of Human Central Nervous System Stem Cells in Subjects With Geographic Atrophy of Age-Related Macular Degeneration
Long-term follow-up safety study of human central nervous system stem cells in geographic atrophy due to age-related macular degeneration ha…
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CLINICAL_TRIALS trial_result · 2016-03-16Clinical Trial Update: Efficacy, Safety And Tolerability Study Of RN6G In Subjects With Geographic Atrophy Secondary to Age-related Macular Degeneration [Phase 2]
Phase 2 trial evaluating the efficacy, safety, and tolerability of RN6G in geographic atrophy associated with age-related macular degenerati…
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CLINICAL_TRIALS trial_result · 2016-01-18Clinical Trial Update: Pharmacokinetic and Pharmacodynamic Study of Emixustat in Subjects With Geographic Atrophy Associated With Dry Age-Related Macular Degeneration [Phase 1]
Phase 1 pharmacokinetic and pharmacodynamic study of emixustat in subjects with geographic atrophy associated with dry age-related macular d…
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CLINICAL_TRIALS trial_result · 2015-12-10Clinical Trial Update: Intravitreal Injections of Sirolimus in the Treatment of Geographic Atrophy [Phase 2]
Phase 2 trial evaluating intravitreal sirolimus for geographic atrophy has been terminated.
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CLINICAL_TRIALS trial_result · 2015-11-30Clinical Trial Update: Evaluation of the Precision of the Microperimetry Function of the Spectral OCT/SLO
This clinical trial update evaluates the precision of microperimetry measurements performed with the Spectral OCT/SLO platform. The study fo…
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CLINICAL_TRIALS trial_result · 2015-05-29Clinical Trial Update: Fluocinolone Acetonide Intravitreal Inserts in Geographic Atrophy [Phase 2]
A Phase 2 trial assessing fluocinolone acetonide intravitreal inserts for geographic atrophy due to age-related macular degeneration has bee…
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CLINICAL_TRIALS trial_result · 2015-03-24Clinical Trial Update: Evolution and Risk Factors Associated With Geographic Atrophy Progression
This clinical trial update examines how geographic atrophy progresses and what factors influence its rate of progression. The study is noted…
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CLINICAL_TRIALS trial_result · 2014-07-03Clinical Trial Update: Geographic Atrophy Treatment Evaluation [Phase 3]
A Phase 3 trial evaluating a treatment for geographic atrophy associated with age-related macular degeneration conducted by Alcon was termin…
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CLINICAL_TRIALS trial_result · 2014-05-09Clinical Trial Update: Sirolimus for Advanced Age-Related Macular Degeneration [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluated sirolimus for advanced age-related macular degeneration and geographic atrophy; results were posted aft…
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CLINICAL_TRIALS trial_result · 2014-03-11Clinical Trial Update: Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ACU-4429 in Subjects With Geographic Atrophy [Phase 2]
Phase 2 trial evaluating the safety, tolerability, pharmacokinetics and pharmacodynamics of ACU-4429 in geographic atrophy due to dry age-re…
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CLINICAL_TRIALS trial_result · 2014-01-20Clinical Trial Update: A Multicenter, Proof-Of-Concept Study Of Intravitreal AL-78898A In Patients With Geographic Atrophy (GA) Associated With Age-Related Macular Degeneration (AMD) [Phase 2]
A multicenter Phase 2 proof-of-concept trial of intravitreal AL-78898A in geographic atrophy due to age-related macular degeneration was ter…
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CLINICAL_TRIALS trial_result · 2013-11-14Clinical Trial Update: Cirrus HD-OCT Measurement of Area of Increased Light Penetration Under the Retinal Pigment Epithelium (RPE)
Clinical trial update reports completion and results posting for Cirrus HD-OCT measurement of the area of increased light penetration under …
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CLINICAL_TRIALS trial_result · 2012-08-16Clinical Trial Update: A Population-based Study of Macular Choroidal Neovascularization in a Chinese Population
A population-based study in China examining choroidal neovascularization in geographic atrophy and wet age-related macular degeneration.
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CLINICAL_TRIALS trial_result · 2011-07-29Clinical Trial Update: OT-551 Antioxidant Eye Drops to Treat Geographic Atrophy in Age-Related Macular Degeneration [Phase 2]
Phase 2 clinical trial evaluating OT-551 antioxidant eye drops for geographic atrophy in age-related macular degeneration completed with res…
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CLINICAL_TRIALS trial_result · 2010-06-22Clinical Trial Update: Study of Fenretinide in the Treatment of Geographic Atrophy Associated With Dry Age-Related Macular Degeneration [Phase 2]
A Phase 2 study evaluating fenretinide for geographic atrophy in dry age-related macular degeneration has completed.
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CLINICAL_TRIALS trial_result · 2010-03-02Clinical Trial Update: The Natural History of Geographic Atrophy Progression (GAP) Study
The GAP study investigated the natural history of geographic atrophy progression in age-related macular degeneration, and the trial has been…