Geographic Atrophy
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Intravitreal (IVT) Pozelimab for Geographic Atrophy (GA) in Adult Participants [Phase 1]
A Phase 1 clinical trial evaluating intravitreal pozelimab for geographic atrophy in adults is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Safety and Clinical Applicability of Transcorneal Electrical Stimulation (TES) in Geographic Atrophy [NA]
Clinical trial update on safety and clinical applicability of transcorneal electrical stimulation for Geographic Atrophy due to age-related …
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Phase 2 Study of ADX-038 in Participants With Geographic Atrophy [Phase 2]
Phase 2 trial of ADX-038 for geographic atrophy secondary to age-related macular degeneration is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette); Adaptive Optics (AO) Retinal Imaging Substudy in Association With Study GR44251 [Phase 2]
Phase 2 study update evaluating Opregen for Geographic Atrophy due to Age-related Macular Degeneration, including optimization of subretinal…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic Atrophy
A ClinicalTrials.gov study is recruiting to observe how Avacincaptad Pegol (Izervay) is used in clinical practice for geographic atrophy and…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Safety and Efficacy Study of a One-time Intravitreal Injection of SAR446597 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration [Phase 1, Phase 2]
A one-time intravitreal injection of SAR446597 for Geographic Atrophy due to Age-related Macular Degeneration is in a combined Phase 1/2 tri…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Real-time Acoustic Biofeedback for Enhancing Fixation Stability: A Proof-of-concept Study to Improve Ophthalmic Imaging Diagnostic Quality [NA]
A proof-of-concept clinical trial evaluating real-time acoustic biofeedback to stabilize fixation and improve ophthalmic imaging quality in …
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Microcurrent Stimulation Therapy for Intermediate to Advanced Nonexudative Age-related Macular Degeneration [NA]
Clinical trial update indicating that Microcurrent Stimulation Therapy is recruiting for intermediate to advanced nonexudative age-related m…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD) [Phase 2]
A long-term extension Phase 2 trial update for Janssen's gene therapy JNJ-81201887 (AAVCAGsCD59) in geographic atrophy due to age-related ma…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy [Phase 3]
A Phase 3 clinical trial is evaluating subcutaneously administered pozelimab with cemdisiran or cemdisiran alone in adults with geographic a…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Study to Investigate Efficacy and Safety of FWY003 Compared With Placebo in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration [Phase 2]
A Phase 2 clinical trial evaluating FWY003 versus placebo for geographic atrophy secondary to age-related macular degeneration is currently …
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: A Phase IIb Randomized, Multicenter Trial of Subretinal CPCB-RPE1 in Advanced Dry AMD (Geographic Atrophy) [Phase 2]
Phase IIb randomized, multicenter trial evaluating subretinal CPCB-RPE1 for advanced dry age-related macular degeneration with geographic at…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: A Non-Interventional Study Observing Short-Term Progression in Geographic Atrophy (GA)
This non-interventional study aims to observe short-term progression in geographic atrophy due to age-related macular degeneration, with rec…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: An Optimised GA Interventional Trial (Opti-GAIN) to Test if Treatment With CTx001 is Safe and Works for People With Geographic Atrophy (GA) [Phase 1, Phase 2]
Opti-GAIN is a Phase 1/2 interventional trial evaluating the safety and potential efficacy of CTx001 for Geographic Atrophy due to age-relat…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: A Prospective, Multicenter, Open-Label, Observational Phase 4 Study to Evaluate Real-World Safety, Tolerability, and Treatment Patterns of Pegcetacoplan (Syfovre) in Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration
A Phase 4 prospective, multicenter, open-label observational study to evaluate real-world safety, tolerability, and treatment patterns of pe…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: A Study About the Safety of ASP3021 Eye Injections and if They Help People in Japan With Vision Loss From Age-related Macular Degeneration [Phase 4]
Phase 4 study in Japan evaluating the safety and potential efficacy of ASP3021 eye injections for vision loss due to Geographic Atrophy and …
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Validation of Virtual Reality Tests for the Assessment of Patients With Age-related Macular Degeneration as Clinical Endpoints [NA]
This clinical trial aims to validate virtual reality-based tests as endpoints for assessing age-related macular degeneration, including dry …
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Evaluating the Relationship Between Function and Structure in ARCHER II-like Population Using Data From a Natural History Cohort
Completed study examining the relationship between function and structure in an ARCHER II–like population using data from a natural history …
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Autologous Transplantation of Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for Geographic Atrophy Associated With Age-Related Macular Degeneration [Phase 1, Phase 2]
An early-stage clinical trial is evaluating autologous induced pluripotent stem cell-derived retinal pigment epithelium transplantation for …
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: A Study to Test Whether BI 771716 Helps People With an Advanced Form of Age-related Macular Degeneration (AMD) Called Geographic Atrophy [Phase 2]
Phase 2 trial update of BI 771716 for geographic atrophy, a form of age-related macular degeneration, currently active_not_recruiting.
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: A Phase 1/2 Study to Evaluate the Safety and Efficacy of Intravitreal Administration of BS01 in Patients With Geographic Atrophy Secondary to Dry AMD [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study evaluating intravitreal BS01 for geographic atrophy secondary to dry age-related macu…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: A Study of the Safety and Tolerability of ASP7317 in Senior Adults Who Are Losing Their Clear, Sharp Central Vision Due to Geographic Atrophy Secondary to Dry Age-related Macular Degeneration [Phase 1]
Phase 1 study to evaluate the safety and tolerability of ASP7317 in senior adults with geographic atrophy secondary to dry age-related macul…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Phase 3, Randomized, Placebo-Controlled Study of Tinlarebant to Explore Safety and Efficacy in Geographic Atrophy [Phase 3]
Belite Bio reports a Phase 3 randomized, placebo-controlled trial to evaluate the safety and efficacy of Tinlarebant in geographic atrophy, …
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Wide Field OCTA in Ocular Diseases
Clinical trial update on a wide-field optical coherence tomography angiography (OCTA) study across several ocular diseases, sponsored by IRC…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: SGLT2 Inhibitors in Geographic Atrophy [Phase 2]
A Phase 2 clinical trial is evaluating SGLT2 inhibitors for geographic atrophy, an advanced form of age-related macular degeneration, and is…