Geographic Atrophy
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CLINICAL_TRIALS trial_result · 2026-07-29Clinical Trial Results: Retinal Fundus Flavoprotein Fluorescence in Age Related Macular Degeneration [NA]
Clinical trial results for retinal fundus flavoprotein fluorescence in geographic atrophy and age-related macular degeneration have been com…
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CLINICAL_TRIALS trial_result · 2026-06-15Clinical Trial Results: COmparison of Clarus and Optos Ultrawide Field Imaging Systems for Geographic Atrophy [NA]
A completed clinical trial comparing two ultrawide field imaging systems (Clarus and Optos) for geographic atrophy in age-related macular de…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Intravitreal (IVT) Pozelimab for Geographic Atrophy (GA) in Adult Participants [Phase 1]
A Phase 1 clinical trial evaluating intravitreal pozelimab for geographic atrophy in adults is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Safety and Clinical Applicability of Transcorneal Electrical Stimulation (TES) in Geographic Atrophy [NA]
Clinical trial update on safety and clinical applicability of transcorneal electrical stimulation for Geographic Atrophy due to age-related …
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Phase 2 Study of ADX-038 in Participants With Geographic Atrophy [Phase 2]
Phase 2 trial of ADX-038 for geographic atrophy secondary to age-related macular degeneration is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette); Adaptive Optics (AO) Retinal Imaging Substudy in Association With Study GR44251 [Phase 2]
Phase 2 study update evaluating Opregen for Geographic Atrophy due to Age-related Macular Degeneration, including optimization of subretinal…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic Atrophy
A ClinicalTrials.gov study is recruiting to observe how Avacincaptad Pegol (Izervay) is used in clinical practice for geographic atrophy and…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Safety and Efficacy Study of a One-time Intravitreal Injection of SAR446597 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration [Phase 1, Phase 2]
A one-time intravitreal injection of SAR446597 for Geographic Atrophy due to Age-related Macular Degeneration is in a combined Phase 1/2 tri…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Avacincaptad Pegol Open-Label Extension for Patients With Geographic Atrophy [Phase 3]
An open-label extension of avacincaptad pegol in geographic atrophy has completed Phase 3, with results posted on April 14, 2026. The study …
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Real-time Acoustic Biofeedback for Enhancing Fixation Stability: A Proof-of-concept Study to Improve Ophthalmic Imaging Diagnostic Quality [NA]
A proof-of-concept clinical trial evaluating real-time acoustic biofeedback to stabilize fixation and improve ophthalmic imaging quality in …
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Microcurrent Stimulation Therapy for Intermediate to Advanced Nonexudative Age-related Macular Degeneration [NA]
Clinical trial update indicating that Microcurrent Stimulation Therapy is recruiting for intermediate to advanced nonexudative age-related m…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD) [Phase 2]
A long-term extension Phase 2 trial update for Janssen's gene therapy JNJ-81201887 (AAVCAGsCD59) in geographic atrophy due to age-related ma…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy [Phase 3]
A Phase 3 clinical trial is evaluating subcutaneously administered pozelimab with cemdisiran or cemdisiran alone in adults with geographic a…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Study to Investigate Efficacy and Safety of FWY003 Compared With Placebo in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration [Phase 2]
A Phase 2 clinical trial evaluating FWY003 versus placebo for geographic atrophy secondary to age-related macular degeneration is currently …
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: A Study to Investigate Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), and Immunogenicity of RO7669330 in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD) [Phase 1]
Phase 1 study evaluating safety, tolerability, pharmacokinetics, pharmacodynamics, and immunogenicity of RO7669330 in geographic atrophy due…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: A Phase IIb Randomized, Multicenter Trial of Subretinal CPCB-RPE1 in Advanced Dry AMD (Geographic Atrophy) [Phase 2]
Phase IIb randomized, multicenter trial evaluating subretinal CPCB-RPE1 for advanced dry age-related macular degeneration with geographic at…
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: Natural History of Geographic Atrophy Associated With Age-Related Macular Degeneration
This clinical trial update notes that the National Eye Institute-sponsored study on the natural history of geographic atrophy in age-related…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: A Non-Interventional Study Observing Short-Term Progression in Geographic Atrophy (GA)
This non-interventional study aims to observe short-term progression in geographic atrophy due to age-related macular degeneration, with rec…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: An Optimised GA Interventional Trial (Opti-GAIN) to Test if Treatment With CTx001 is Safe and Works for People With Geographic Atrophy (GA) [Phase 1, Phase 2]
Opti-GAIN is a Phase 1/2 interventional trial evaluating the safety and potential efficacy of CTx001 for Geographic Atrophy due to age-relat…
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CLINICAL_TRIALS trial_result · 2026-03-13Clinical Trial Update: A Study to Evaluate Intravitreal JNJ-81201887 (AAVCAGsCD59) Compared to Sham Procedure for the Treatment of Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD) [Phase 2]
A Phase 2 trial evaluating intravitreal JNJ-81201887 (AAVCAGsCD59) versus sham for geographic atrophy due to age-related macular degeneratio…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: A Prospective, Multicenter, Open-Label, Observational Phase 4 Study to Evaluate Real-World Safety, Tolerability, and Treatment Patterns of Pegcetacoplan (Syfovre) in Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration
A Phase 4 prospective, multicenter, open-label observational study to evaluate real-world safety, tolerability, and treatment patterns of pe…
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FDA approval · 2026-02-27FDA Approved: IZERVAY — Supplemental Application (Astellas Pharma US, Inc.)
The FDA approved a supplemental application for IZERVAY (avacincaptad pegol) from Astellas Pharma US, expanding its label for geographic atr…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: A Study About the Safety of ASP3021 Eye Injections and if They Help People in Japan With Vision Loss From Age-related Macular Degeneration [Phase 4]
Phase 4 study in Japan evaluating the safety and potential efficacy of ASP3021 eye injections for vision loss due to Geographic Atrophy and …
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Validation of Virtual Reality Tests for the Assessment of Patients With Age-related Macular Degeneration as Clinical Endpoints [NA]
This clinical trial aims to validate virtual reality-based tests as endpoints for assessing age-related macular degeneration, including dry …
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CLINICAL_TRIALS trial_result · 2026-02-24Clinical Trial Update: Subtenon PRP Injection for Geographic Atrophy in Dry Age-Related Macular Degeneration [NA]
This entry notes the completion of a clinical trial evaluating subtenon platelet-rich plasma (PRP) injections for geographic atrophy in dry …