Gastrointestinal Stromal Tumor
📧 Sign up to get email alerts when something new happens for Gastrointestinal Stromal Tumor.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2020-04-06Clinical Trial Update: Efficacy of Ferric Carboxymaltose in Gastrointestinal Stromal Tumor (GIST) Patients With Iron Deficiency Anemia (IDA) Receiving Systemic Therapy [Phase 2]
Phase 2 trial investigating ferric carboxymaltose for iron deficiency anemia in patients with gastrointestinal stromal tumor undergoing syst…
-
CLINICAL_TRIALS trial_result · 2020-03-30Clinical Trial Update: BGJ398 in Combination With Imatinib Mesylate in Patients With Untreated Advanced Gastrointestinal Stromal Tumor (GIST) [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating BGJ398 in combination with imatinib in untreated advanced GIST has completed with results posted.
-
FDA approval · 2020-01-09FDA Approved: AYVAKIT — Original Application (Blueprint Medicines Corporation)
FDA approved AYVAKIT (avapritinib) under the original NDA for adults with unresectable or metastatic gastrointestinal stromal tumors harbori…
-
FDA approval · 2020-01-09FDA Approved: IMATINIB MESYLATE — Supplemental Application (Teva Pharmaceuticals USA, Inc.)
FDA approved a supplemental application for imatinib mesylate from Teva Pharmaceuticals USA, Inc., under ANDA204285.
-
CLINICAL_TRIALS trial_result · 2020-01-07Clinical Trial Update: Management of Imatinib-associated Severe Skin Rash in Patients With Gastrointestinal Stromal Tumor [Phase 2]
Phase 2 trial update addressing management of imatinib-associated severe skin rash in patients with gastrointestinal stromal tumor (GIST).
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2019-10-09Clinical Trial Update: A Combination Clinical Study of PLX3397 and Pembrolizumab To Treat Advanced Melanoma and Other Solid Tumors [Phase 1, Phase 2]
A phase 1/2 study evaluating PLX3397 in combination with pembrolizumab in advanced melanoma and other solid tumors was terminated; results w…
-
CLINICAL_TRIALS trial_result · 2019-09-26Clinical Trial Update: Efficacy and Safety of Anlotinib in Patients With Advanced Gastrointestinal Stromal Tumor After Failure of Imatinib: a Prospective, Single Arm and Multicenter Trial [Phase 2]
Phase 2 trial evaluating the efficacy and safety of anlotinib in advanced gastrointestinal stromal tumor after imatinib failure.
-
CLINICAL_TRIALS trial_result · 2019-09-12Clinical Trial Update: Phase Ib Study of SUnitinib Alternating With REgorafenib in Patients With Metastatic and/or Unresectable GIST [Phase 1]
Phase Ib trial updates on alternating Sunitinib and Regorafenib in metastatic/unresectable gastrointestinal stromal tumor (GIST); study comp…
-
CLINICAL_TRIALS trial_result · 2019-07-23Clinical Trial Update: Phase II Trial of Vandetanib in Children and Adults With Wild-Type Gastrointestinal Stromal Tumors [Phase 2]
Phase II trial of vandetanib in children and adults with wild-type gastrointestinal stromal tumors (GIST) completed; results posted.
-
CLINICAL_TRIALS trial_result · 2019-06-17Clinical Trial Update: Dasatinib as First-Line Therapy in Treating Patients With Gastrointestinal Stromal Tumors [Phase 2]
Phase 2 clinical trial update evaluating dasatinib as first-line therapy in patients with gastrointestinal stromal tumor.
-
CLINICAL_TRIALS trial_result · 2019-01-30Clinical Trial Update: Study of Tumor Samples in Patients Undergoing Treatment for Gastrointestinal Stromal Tumors on Clinical Trial ACOSOG-Z9001
A completed clinical trial (ACOSOG-Z9001) studied tumor samples from patients undergoing treatment for Gastrointestinal Stromal Tumors.
-
FDA approval · 2019-01-17FDA Approved: IMATINIB MESYLATE — Original Application (Ascend Laboratories, LLC)
FDA approved Ascend Laboratories' imatinib mesylate as an original application for a generic version of the cancer drug, for the same indica…
-
FDA approval · 2019-01-17FDA Approved: IMATINIB MESYLATE — Original Application (Chartwell RX, LLC)
FDA approves an original ANDA for imatinib mesylate, granting Chartwell RX, LLC a generic version (ANDA 208429).
-
CLINICAL_TRIALS trial_result · 2018-12-14Clinical Trial Update: Masitinib in Patients With Localized, Primary GIST After Complete Surgery and With High Risk of Recurrence [Phase 3]
Phase 3 trial of masitinib in localized, high-risk gastrointestinal stromal tumor after complete surgery was terminated.
-
CLINICAL_TRIALS trial_result · 2018-12-11Clinical Trial Update: Masitinib in Patients With Gastro-Intestinal Stromal Tumour Resistant to Imatinib [Phase 2]
Phase 2 clinical trial update for masitinib in patients with gastrointestinal stromal tumor resistant to imatinib has completed.
-
FDA approval · 2018-08-13FDA Approved: IMATINIB — Original Application (Dr.Reddy's Laboratories Inc)
FDA approved the original application for imatinib from Dr. Reddy's Laboratories Inc, enabling the generic product to be marketed in the Uni…
-
CLINICAL_TRIALS research · 2018-07-26Clinical Trial Update: Laparoscopic Endoscopic Cooperative Surgery in the Treatment of Gastric Stromal Tumors [NA]
Clinical trial update about laparoscopic endoscopic cooperative surgery for gastric gastrointestinal stromal tumors; no results or phase inf…
-
CLINICAL_TRIALS trial_result · 2018-07-09Clinical Trial Update: Imatinib Mesylate or Observation Only in Treating Patients Who Have Undergone Surgery for Localized Gastrointestinal Stromal Tumor [Phase 3]
This completed Phase 3 trial evaluated adjuvant imatinib mesylate versus observation after surgical resection for localized gastrointestinal…
-
CLINICAL_TRIALS trial_result · 2018-06-28Clinical Trial Update: Study of Crenolanib for the Treatment of Patients With Advanced GIST With the D842-related Mutations and Deletions in the PDGFRA Gene [Phase 2]
Update on a Phase 2 trial of crenolanib in patients with advanced gastrointestinal stromal tumor with D842-related PDGFRA mutations. The stu…
-
CLINICAL_TRIALS trial_result · 2018-04-17Clinical Trial Update: A Study of Famitinib in Patients With Gastrointestinal Stromal Tumor [Phase 2]
A Phase 2 clinical trial evaluating Famitinib in patients with Gastrointestinal Stromal Tumor is ongoing, with the current status not disclo…
-
CLINICAL_TRIALS trial_result · 2018-03-14Clinical Trial Update: Five Year Adjuvant Imatinib Mesylate (Gleevec®) in Gastrointestinal Stromal Tumor (GIST) [Phase 2]
This update reports results from a Phase 2 trial of five years of adjuvant imatinib mesylate (Gleevec) in patients with gastrointestinal str…
-
CLINICAL_TRIALS research · 2018-03-01Clinical Trial Update: To Compare the Efficacy of Surgery Followed by Sunitinib With Surgery Followed by Imatinib in GIST Patients With Progression on Imatinib.
Clinical trial comparing surgery followed by sunitinib versus surgery followed by imatinib in patients with gastrointestinal stromal tumors …
-
CLINICAL_TRIALS trial_result · 2018-02-22Clinical Trial Update: Ph II Study of Perifosine Plus Gleevec for Patients With GIST [Phase 2]
Phase II study evaluating perifosine plus imatinib (Gleevec) in patients with gastrointestinal stromal tumors has completed.
-
CLINICAL_TRIALS trial_result · 2017-11-28Clinical Trial Update: Study on the Influence of Sunitinib and Sorafenib on Fatigue, QoL, Depression in Patients With Metastatic RCC or GIST
A completed clinical trial evaluated the impact of sunitinib and sorafenib on fatigue, quality of life, and depression in patients with meta…
-
FDA approval · 2017-11-16FDA Approved: SUTENT — Supplemental Application (U.S. Pharmaceuticals)
FDA has approved a supplemental application for Sutent (sunitinib malate) submitted by U.S. Pharmaceuticals. This entry documents the supple…