Gastrointestinal Stromal Tumor
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-01-01Clinical Trial Update: The GALLOP-11 Study
The GALLOP-11 trial (NCT05178030) conducted by University Medical Center Groningen for gastrointestinal stromal tumors has completed.
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CLINICAL_TRIALS research · 2024-12-27Clinical Trial Update: A Study of Olverembatinib in SDH-deficient GIST. [Phase 3]
This Phase 3 clinical trial update describes evaluating olverembatinib in SDH-deficient gastrointestinal stromal tumor (GIST) and indicates …
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CLINICAL_TRIALS trial_result · 2024-12-13Clinical Trial Update: A Drug-drug Interaction Study of Avapritinib and Midazolam [Phase 1]
Phase 1 drug-drug interaction study of avapritinib with midazolam has completed. The snippet does not provide study results.
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FDA approval · 2024-12-09FDA Approved: IMATINIB MESYLATE — Supplemental Application (Mylan Pharmaceuticals Inc.)
The FDA approved a supplemental application for imatinib mesylate from Mylan Pharmaceuticals, effectively authorizing a supplemental approva…
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CLINICAL_TRIALS trial_result · 2024-11-26Clinical Trial Update: Study for Patients Previously Treated in Avapritinib Clinical Trials [Phase 4]
Phase 4 clinical trial update for patients previously treated with avapritinib in gastrointestinal stromal tumors has completed and results …
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FDA approval · 2024-11-22FDA Approved: IMKELDI — Original Application (Shorla Oncology Inc.,)
FDA approved IMKELDI (imatinib oral) under an original NDA from Shorla Oncology, authorizing a new imatinib product for several cancers incl…
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CLINICAL_TRIALS research · 2024-11-04Clinical Trial Update: Temozolomide (TMZ) in Advanced Succinate Dehydrogenase (SDH)-Mutant/Deficient Gastrointestinal Stromal Tumor (GIST) [Phase 2]
Phase 2 clinical trial evaluating temozolomide in advanced SDH-mutant/deficient gastrointestinal stromal tumors is currently active but not …
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CLINICAL_TRIALS trial_result · 2024-10-08Clinical Trial Update: Correlation Between Imatinib Trough Concentration and Efficacy in Advanced GIST Patients with Different Genotypes
A clinical trial update examining the relationship between imatinib trough concentrations and efficacy in advanced gastrointestinal stromal …
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CLINICAL_TRIALS trial_result · 2024-09-23Clinical Trial Update: Registry For Temsirolimus, Sunitinib, And Axitinib Treated Patients With Metastatic Renal Cell Carcinoma (mRCC), Mantle Cell Lymphoma (MCL), And Gastro-Intestinal Stroma Tumor (GIST) [STAR-TOR]
Pfizer-sponsored STAR-TOR registry study update reports completion and posted results for a three-drug regimen of temsirolimus, sunitinib, a…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: A Drug-Drug Interaction Study to Evaluate the Effect of Ripretinib on the Pharmacokinetics of a CYP2C8 Probe Substrate in Patients with Advanced GIST [Phase 1]
Phase 1 trial update describing a drug-drug interaction study to assess how ripretinib affects the pharmacokinetics of a CYP2C8 probe substr…
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CLINICAL_TRIALS research · 2024-08-09Clinical Trial Update: Individual Patient Compassionate Use of Crenolanib
Clinical trial update indicating that crenolanib is available for individual patient compassionate use in cancers with FLT3-ITD/FLT3-TKD mut…
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CLINICAL_TRIALS trial_result · 2024-08-02Clinical Trial Update: A Study to Investigate the Safety and Efficacy of AT13387, Alone or in Combination With Imatinib, in Patients With GIST [Phase 2]
Phase 2 trial evaluating AT13387 alone or with imatinib in gastrointestinal stromal tumor (GIST) has completed safety and efficacy assessmen…
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CLINICAL_TRIALS trial_result · 2024-07-16Clinical Trial Update: GIST and Memory and Attention Adaptation Training [NA]
Clinical trial investigating Memory and Attention Adaptation Training for malignant gastrointestinal stromal tumors was terminated.
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CLINICAL_TRIALS trial_result · 2024-06-26Clinical Trial Update: Advanced Gastrointestinal Endoscopic Imaging [NA]
A clinical trial update on Advanced Gastrointestinal Endoscopic Imaging shows the study was terminated and results have been posted.
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CLINICAL_TRIALS trial_result · 2024-06-18Clinical Trial Update: Multicentre Placebo-controlled Double-blinded Phase II Study of Lenvatinib Efficacy in Patients With Locally Advanced or Metastatic GIST (Gastrointestinal Stromal Tumor) After Imatinib/Sunitinib Failure [Phase 2]
This is a multicentre, placebo-controlled, double-blind Phase II trial evaluating lenvatinib in patients with locally advanced or metastatic…
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CLINICAL_TRIALS trial_result · 2024-06-11Clinical Trial Update: Epacadostat and Pembrolizumab in Patients With GIST [Phase 2]
Phase 2 trial evaluating the combination of epacadostat and pembrolizumab in gastrointestinal stromal tumors was terminated; results/status …
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FDA approval · 2024-03-01FDA Approved: GLEEVEC — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for GLEEVEC (imatinib mesylate) submitted by Novartis Pharmaceuticals Corporation. This action confi…
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FDA approval · 2024-01-05FDA Approved: IMATINIB MESYLATE — Supplemental Application (Mylan Pharmaceuticals Inc.)
FDA approved a supplemental application from Mylan Pharmaceuticals for imatinib mesylate, enabling a generic version to be marketed under AN…
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CLINICAL_TRIALS trial_result · 2024-01-02Clinical Trial Update: A Study of Ripretinib vs Sunitinib in Advanced GIST Patients After Treatment With Imatinib [Phase 3]
This update reports the results of a Phase 3 study comparing ripretinib to sunitinib in advanced gastrointestinal stromal tumors after imati…
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CLINICAL_TRIALS trial_result · 2024-01-02Clinical Trial Update: Imatinib Dose Escalation to 800 mg/Day in Korean Patients With Metastatic or Unresectable GIST Harboring KIT Exon 9 Mutation: KENEDI [Phase 2]
Phase 2 trial assessing imatinib dose escalation to 800 mg/day in Korean patients with metastatic or unresectable GIST harboring KIT exon 9 …
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FDA approval · 2023-08-21FDA Approved: SUNITINIB MALATE — Supplemental Application (NorthStar RxLLC)
The FDA approved a supplemental application for SUNITINIB MALATE (sunitinib malate) filed by NorthStar RxLLC.
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FDA approval · 2023-08-21FDA Approved: SUNITINIB MALATE — Original Application (Novugen Pharma (USA) LLC.)
FDA approves a generic version of sunitinib malate from Novugen Pharma (USA) LLC under an Original Application (ANDA 218012).
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FDA approval · 2023-08-16FDA Approved: IMATINIB — Supplemental Application (Dr.Reddy's Laboratories Inc)
FDA approved a supplemental application for Imatinib from Dr. Reddy's Laboratories Inc, resulting in regulatory approval for a change to the…
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CLINICAL_TRIALS trial_result · 2023-07-21Clinical Trial Update: Surgery in Treating Patients With Liver Metastasis From a Gastrointestinal Stromal Tumor [Phase 2]
Phase 2 clinical trial update on liver metastasis surgery for gastrointestinal stromal tumor (GIST).
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CLINICAL_TRIALS trial_result · 2023-07-21Clinical Trial Update: Imatinib Mesylate in Treating Patients With Liver Metastasis From a Gastrointestinal Stromal Tumor [Phase 2]
Phase 2 clinical trial evaluating imatinib mesylate for liver metastases from gastrointestinal stromal tumors has completed.