Gastrointestinal Stromal Tumor
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-06-11Clinical Trial Update: Epacadostat and Pembrolizumab in Patients With GIST [Phase 2]
Phase 2 trial evaluating the combination of epacadostat and pembrolizumab in gastrointestinal stromal tumors was terminated; results/status …
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CLINICAL_TRIALS trial_result · 2024-01-02Clinical Trial Update: A Study of Ripretinib vs Sunitinib in Advanced GIST Patients After Treatment With Imatinib [Phase 3]
This update reports the results of a Phase 3 study comparing ripretinib to sunitinib in advanced gastrointestinal stromal tumors after imati…
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CLINICAL_TRIALS trial_result · 2024-01-02Clinical Trial Update: Imatinib Dose Escalation to 800 mg/Day in Korean Patients With Metastatic or Unresectable GIST Harboring KIT Exon 9 Mutation: KENEDI [Phase 2]
Phase 2 trial assessing imatinib dose escalation to 800 mg/day in Korean patients with metastatic or unresectable GIST harboring KIT exon 9 …
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CLINICAL_TRIALS trial_result · 2023-07-21Clinical Trial Update: Surgery in Treating Patients With Liver Metastasis From a Gastrointestinal Stromal Tumor [Phase 2]
Phase 2 clinical trial update on liver metastasis surgery for gastrointestinal stromal tumor (GIST).
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CLINICAL_TRIALS trial_result · 2023-07-21Clinical Trial Update: Imatinib Mesylate in Treating Patients With Liver Metastasis From a Gastrointestinal Stromal Tumor [Phase 2]
Phase 2 clinical trial evaluating imatinib mesylate for liver metastases from gastrointestinal stromal tumors has completed.
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CLINICAL_TRIALS trial_result · 2023-07-07Clinical Trial Update: A Randomised Trial of Imatinib Alternating With Regorafenib Compared to Imatinib Alone for the First Line Treatment of Advanced Gastrointestinal Stromal Tumour (GIST) [Phase 2]
Phase 2 randomized trial assessing alternating imatinib with regorafenib versus imatinib alone as first-line therapy for advanced gastrointe…
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CLINICAL_TRIALS trial_result · 2022-08-18Clinical Trial Update: Nivolumab With or Without Ipilimumab in Treating Patients With Gastrointestinal Stromal Tumor That Is Metastatic or Cannot Be Removed by Surgery [Phase 2]
Phase 2 trial evaluating nivolumab with or without ipilimumab in metastatic or unresectable gastrointestinal stromal tumor (GIST).
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CLINICAL_TRIALS trial_result · 2021-07-15Clinical Trial Update: Ph II CABOGIST in GIST [Phase 2]
Phase II trial update for CABOGIST in metastatic gastrointestinal stromal tumor has completed.
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CLINICAL_TRIALS trial_result · 2021-05-14Clinical Trial Update: (VOYAGER) Study of Avapritinib vs Regorafenib in Patients With Locally Advanced Unresectable or Metastatic GIST [Phase 3]
Phase 3 trial comparing avapritinib to regorafenib in locally advanced unresectable or metastatic GIST has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-05-10Clinical Trial Update: A Phase II Trial of the DNA Methyl Transferase Inhibitor, Guadecitabine (SGI-110), in Children and Adults With Wild Type GIST,Pheochromocytoma and Paraganglioma Associated With Succinate Dehydrogenase Deficiency and HLRCC-associated Kidney Cancer [Phase 2]
A Phase II trial of the DNA methyltransferase inhibitor guadecitabine (SGI-110) in children and adults with wild-type GIST, paraganglioma, p…
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CLINICAL_TRIALS trial_result · 2021-02-18Clinical Trial Update: NIR Fluorescence Imaging With ICG for the Intraoperative Identification of Gastrointestinal Stromal Cell Tumours [Phase 2, Phase 3]
A clinical trial update on NIR fluorescence imaging with ICG for intraoperative identification of gastrointestinal stromal tumors (GIST) acr…
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CLINICAL_TRIALS trial_result · 2021-01-22Clinical Trial Update: Randomized Trial of Crenolanib in Subjects With D842V Mutated GIST [Phase 3]
A randomized Phase 3 trial evaluating crenolanib in GIST patients with the D842V PDGFRA mutation.
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CLINICAL_TRIALS trial_result · 2021-01-20Clinical Trial Update: Efficacy and Safety of PD-0332991 in Advanced Gastrointestinal Stromal Tumors Refractory to Imatinib and Sunitinib [Phase 2]
Phase 2 trial evaluating the efficacy and safety of PD-0332991 (palbociclib) in advanced gastrointestinal stromal tumors refractory to imati…
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CLINICAL_TRIALS trial_result · 2020-09-10Clinical Trial Update: Treatment of Patients With Everolimus and Imatinib Mesylate Who Have Progressive Gastro Intestinal Stromal Tumors (GIST) and Are Resistant to Imatinib Mesylate [Phase 4]
Phase 4 trial update assessing the combination of everolimus and imatinib for progressive gastrointestinal stromal tumors resistant to imati…
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CLINICAL_TRIALS trial_result · 2020-07-13Clinical Trial Update: L-carnitine vs Placebo for the Treatment of Muscle Cramps After Imatinib in Gastrointestinal Stromal Tumors [Phase 3]
Phase 3 clinical trial comparing L-carnitine to placebo for treating muscle cramps after imatinib in patients with gastrointestinal stromal …
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CLINICAL_TRIALS trial_result · 2020-06-16Clinical Trial Update: Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Sarcoma That Cannot Be Removed by Surgery [Phase 2]
A Phase 2 trial evaluating nivolumab with or without ipilimumab in metastatic or unresectable sarcoma shows results from a completed study.
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CLINICAL_TRIALS trial_result · 2020-04-06Clinical Trial Update: Efficacy of Ferric Carboxymaltose in Gastrointestinal Stromal Tumor (GIST) Patients With Iron Deficiency Anemia (IDA) Receiving Systemic Therapy [Phase 2]
Phase 2 trial investigating ferric carboxymaltose for iron deficiency anemia in patients with gastrointestinal stromal tumor undergoing syst…
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CLINICAL_TRIALS trial_result · 2020-03-30Clinical Trial Update: BGJ398 in Combination With Imatinib Mesylate in Patients With Untreated Advanced Gastrointestinal Stromal Tumor (GIST) [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating BGJ398 in combination with imatinib in untreated advanced GIST has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-01-07Clinical Trial Update: Management of Imatinib-associated Severe Skin Rash in Patients With Gastrointestinal Stromal Tumor [Phase 2]
Phase 2 trial update addressing management of imatinib-associated severe skin rash in patients with gastrointestinal stromal tumor (GIST).
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CLINICAL_TRIALS trial_result · 2019-10-09Clinical Trial Update: A Combination Clinical Study of PLX3397 and Pembrolizumab To Treat Advanced Melanoma and Other Solid Tumors [Phase 1, Phase 2]
A phase 1/2 study evaluating PLX3397 in combination with pembrolizumab in advanced melanoma and other solid tumors was terminated; results w…
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CLINICAL_TRIALS trial_result · 2019-09-26Clinical Trial Update: Efficacy and Safety of Anlotinib in Patients With Advanced Gastrointestinal Stromal Tumor After Failure of Imatinib: a Prospective, Single Arm and Multicenter Trial [Phase 2]
Phase 2 trial evaluating the efficacy and safety of anlotinib in advanced gastrointestinal stromal tumor after imatinib failure.
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CLINICAL_TRIALS trial_result · 2019-09-12Clinical Trial Update: Phase Ib Study of SUnitinib Alternating With REgorafenib in Patients With Metastatic and/or Unresectable GIST [Phase 1]
Phase Ib trial updates on alternating Sunitinib and Regorafenib in metastatic/unresectable gastrointestinal stromal tumor (GIST); study comp…
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CLINICAL_TRIALS trial_result · 2019-07-23Clinical Trial Update: Phase II Trial of Vandetanib in Children and Adults With Wild-Type Gastrointestinal Stromal Tumors [Phase 2]
Phase II trial of vandetanib in children and adults with wild-type gastrointestinal stromal tumors (GIST) completed; results posted.
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CLINICAL_TRIALS trial_result · 2019-06-17Clinical Trial Update: Dasatinib as First-Line Therapy in Treating Patients With Gastrointestinal Stromal Tumors [Phase 2]
Phase 2 clinical trial update evaluating dasatinib as first-line therapy in patients with gastrointestinal stromal tumor.
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CLINICAL_TRIALS trial_result · 2019-01-30Clinical Trial Update: Study of Tumor Samples in Patients Undergoing Treatment for Gastrointestinal Stromal Tumors on Clinical Trial ACOSOG-Z9001
A completed clinical trial (ACOSOG-Z9001) studied tumor samples from patients undergoing treatment for Gastrointestinal Stromal Tumors.