Gastrointestinal Stromal Tumor
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Phase I Trial to Determine the Dose and Evaluate the PK and Safety of Lutetium Lu 177 Edotreotide Therapy in Pediatric Participants With SSTR-positive Tumors [Phase 1]
Phase I clinical trial update evaluating dose, pharmacokinetics, and safety of Lutetium-177-edotreotide therapy in pediatric participants wi…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: A Comprehensive, Multinational GIST Registry
A comprehensive multinational registry study for gastrointestinal stromal tumor (GIST) that is not yet recruiting.
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: MEK162 in Combination With Imatinib Mesylate in Patients With Untreated Advanced Gastrointestinal Stromal Tumor (GIST) [Phase 1, Phase 2]
A clinical trial update describing a Phase 1/2 study of MEK162 in combination with imatinib mesylate for untreated advanced gastrointestinal…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: First-in-human Study of IDRX-42 in Participants With Metastatic and/or Unresectable Gastrointestinal Stromal Tumors [Phase 1]
First-in-human Phase 1 trial of IDRX-42 for metastatic and/or unresectable gastrointestinal stromal tumors (GIST) is currently recruiting.
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: A Study of the c-Kit Specific Antibody-Drug Conjugate NN3201 for Advanced and/or Metastatic Solid Tumors Known to Express c-Kit [Phase 1]
Phase 1 study evaluating NN3201, a c-Kit targeted antibody-drug conjugate, in advanced and/or metastatic solid tumors expressing c-Kit; curr…
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: Resistance Profiling Using Functional Imaging and Next Generation Sequencing in Refractory Gastrointestinal Stomal Tumors (GIST)
A clinical trial update describing a study to profile resistance in refractory gastrointestinal stromal tumor (GIST) using functional imagin…
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: Enhanced Outpatient Symptom Management to Reduce Acute Care Visits Due to Chemotherapy-Related Adverse Events [NA]
A clinical trial at MD Anderson Cancer Center is evaluating enhanced outpatient symptom management to reduce acute care visits caused by che…
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: 5 Years of Adjuvant Imatinib in Patients With Gastrointestinal Stromal Tumor With a High Risk [Phase 2]
Phase 2 trial assessing five years of adjuvant imatinib in patients with high-risk gastrointestinal stromal tumors; recruitment is ongoing.
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: CEH-EUS for Differentiating GISTs and Leiomyomas: A Multicenter Prospective Self-Controlled Study
A multicenter prospective self-controlled clinical trial evaluating contrast-enhanced harmonic endoscopic ultrasound (CEH-EUS) to differenti…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: Multicenter Observational Study of Multimodal AI for Upper GI Mesenchymal Tumor Diagnosis
A multicenter observational study is evaluating multimodal artificial intelligence for diagnosing upper gastrointestinal mesenchymal tumors,…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: A Study of Regorafenib Combined With Envafolimab for Metastatic Gastrointestinal Stromal Tumors With Kit Gene Exon 17 Mutation That Failed Standard Treatment [Phase 2]
A Phase 2 clinical trial is evaluating regorafenib plus Envafolimab for metastatic Gastrointestinal Stromal Tumors with KIT exon 17 mutation…
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: An International Study on Pediatric Patients With Rare Tumors.
An international pediatric clinical trial study focused on rare tumors is currently recruiting, covering multiple tumor types.
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CLINICAL_TRIALS research · 2025-05-13Clinical Trial Update: GIST: Assessment of Tumor Mutations and TKI Plasma Exposure
A completed clinical trial update examining tumor mutation profiles and the plasma exposure of tyrosine kinase inhibitors in gastrointestina…
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CLINICAL_TRIALS research · 2025-04-16Clinical Trial Update: Prospective Evaluation of Cornerstone Robotics Sentire Surgical System in Major Gastrointestinal and Urologic Surgery [NA]
This clinical trial update notes a prospective evaluation of the Cornerstone Robotics Sentire Surgical System in major gastrointestinal and …
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CLINICAL_TRIALS research · 2025-03-27Clinical Trial Update: The Australia and New Zealand Multicentre Upper Gastrointestinal Endoscopic Tissue Resection Study
A multicenter Australia-New Zealand trial evaluating endoscopic tissue resection for upper gastrointestinal cancers; currently recruiting.
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CLINICAL_TRIALS research · 2025-03-21Clinical Trial Update: Observational Study, for Quality Assessment, of Sarcoma in European and Latin American Multidisciplinary NETWORK
An observational quality-assessment study of sarcoma being conducted across European and Latin American multidisciplinary networks; recruitm…
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: Three Versus Five Years of Adjuvant Imatinib as Treatment of Patients With Operable GIST [Phase 3]
An update on a Phase 3 trial comparing three versus five years of adjuvant imatinib in patients with operable gastrointestinal stromal tumor…
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CLINICAL_TRIALS research · 2025-02-26Clinical Trial Update: Avapritinib in the Treatment of Unresectable or Recurrent Metastatic GIST Non-exon18 Mutations of PDGFRA
This clinical trial update covers the investigation of avapritinib for unresectable or recurrent/metastatic gastrointestinal stromal tumors …
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CLINICAL_TRIALS research · 2025-02-26Clinical Trial Update: A Multicenter Study of Avapritinib Efficacy and Safety of Metastatic or Unresectable Gastrointestinal Stromal Tumors
A multicenter clinical trial is evaluating the efficacy and safety of avapritinib for metastatic or unresectable gastrointestinal stromal tu…
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CLINICAL_TRIALS research · 2025-02-26Clinical Trial Update: The Correlation Between Ripretinib Exposure and the Efficacy and Safety in Patients with Advanced GISTs
A clinical trial update examining the relationship between ripretinib exposure and its efficacy and safety in patients with advanced gastroi…
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CLINICAL_TRIALS research · 2025-02-26Clinical Trial Update: Second-line Pharmacotherapy Patterns and Outcomes of Advanced Gastrointestinal Stromal Tumor: A Real-world Study
A real-world study investigating second-line pharmacotherapy patterns and outcomes in advanced gastrointestinal stromal tumors, currently in…
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CLINICAL_TRIALS research · 2024-12-27Clinical Trial Update: A Study of Olverembatinib in SDH-deficient GIST. [Phase 3]
This Phase 3 clinical trial update describes evaluating olverembatinib in SDH-deficient gastrointestinal stromal tumor (GIST) and indicates …
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CLINICAL_TRIALS research · 2024-11-04Clinical Trial Update: Temozolomide (TMZ) in Advanced Succinate Dehydrogenase (SDH)-Mutant/Deficient Gastrointestinal Stromal Tumor (GIST) [Phase 2]
Phase 2 clinical trial evaluating temozolomide in advanced SDH-mutant/deficient gastrointestinal stromal tumors is currently active but not …
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CLINICAL_TRIALS research · 2024-08-09Clinical Trial Update: Individual Patient Compassionate Use of Crenolanib
Clinical trial update indicating that crenolanib is available for individual patient compassionate use in cancers with FLT3-ITD/FLT3-TKD mut…
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CLINICAL_TRIALS research · 2018-07-26Clinical Trial Update: Laparoscopic Endoscopic Cooperative Surgery in the Treatment of Gastric Stromal Tumors [NA]
Clinical trial update about laparoscopic endoscopic cooperative surgery for gastric gastrointestinal stromal tumors; no results or phase inf…