Gastroesophageal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Substudy 06C: A Study of Investigational Agents With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06) [Phase 1, Phase 2]
This is a clinical trial update indicating that Substudy 06C is evaluating pembrolizumab in combination with chemotherapy for first-line loc…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Supportive Oncology Care At Home RCT [NA]
Clinical trial update on an at-home supportive oncology care program; the study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Simvastatin Efficacy in ARID1A Mutated Advanced gastroESophageal Carcinoma Treated With Immunotherapy [Phase 2]
Phase 2 clinical trial exploring simvastatin efficacy in ARID1A-mutated advanced gastroesophageal cancer treated with immunotherapy; current…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Support Through Remote Observation and Nutrition Guidance Program for Individuals With Gastroesophageal Cancer [NA]
A study evaluating a remote observation and nutrition guidance program for individuals with gastroesophageal cancer is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Perioperative Zanidatamab and Chemotherapy for HER2 Positive Gastroesophageal Cancer [Phase 1, Phase 2]
Phase 1/2 study evaluating perioperative zanidatamab with chemotherapy for HER2-positive gastroesophageal cancer; the trial is currently not…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: A First-In-Human Phase I/IIa Study to Evaluate DA 3501 in Patients With Advanced Gastric or Gastro-esophageal Junction Adenocarcinoma and Pancreatic Ductal Adenocarcinoma [Phase 1]
First-in-human phase I/IIa trial evaluating DA 3501 in advanced gastric or gastroesophageal cancer and pancreatic ductal adenocarcinoma; cur…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: A Study to Evaluate Sacituzumab Tirumotecan (MK-2870) in Advanced/Metastatic Gastroesophageal Adenocarcinoma (MK-2870-015) [Phase 3]
A Phase 3 trial evaluating Sacituzumab Tirumotecan (MK-2870) in advanced/metastatic gastroesophageal adenocarcinoma is currently active but …
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Neratinib In Combination With Chemotherapy/Trastuzumab/Pembrolizumab In HER2 Gastroesophageal Cancer [Phase 2]
Phase 2 trial evaluating neratinib in combination with chemotherapy, trastuzumab, and pembrolizumab for HER2-positive gastroesophageal cance…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Synergistic Effects of PD-1 Antibody and Chemotherapy/Targeted Therapy Followed by Surgery-centric Local Treatment in Patients With Limited-metastatic Gastric Cancer [Phase 2]
Phase 2 clinical trial evaluating a PD-1 antibody in combination with chemotherapy or targeted therapy, followed by a surgery-centric local …
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Sample Collection for Ongoing Research and Product Evaluation Study
Natera reports an ongoing study update focused on sample collection for ongoing research and product evaluation; the trial is currently recr…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: sFOLFOXIRI in Advanced Gastroesophageal Cancer, (SAGE) [Phase 2]
Phase 2 clinical trial update evaluating sFOLFOXIRI in advanced gastroesophageal cancer; the study is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-02Clinical Trial Update: Imaging and Blood-Based Biomarkers for the Evaluation of Early Signs of Myocardial Injury After Thoracic Radiation Therapy
This clinical trial update from Ohio State University Comprehensive Cancer Center describes evaluating imaging and blood-based biomarkers to…
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: REACTION (Radiation Enhanced Assessment of Combination Therapies in Immuno-ONcology) - Nivolumab or Nivolumab in Combination With Other Immuno-oncology (IO) Agents After Targeted Systemic Radiation in Patients With Advanced Esophagogastric Cancer [Phase 1, Phase 2]
This entry covers the REACTION trial (NCT03610711) evaluating nivolumab, alone or with other immune checkpoint inhibitors, after targeted sy…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Support Through Remote Observation and Nutrition Guidance (STRONG) Program for Gastroesophageal Cancer (GEC) Patients [NA]
A clinical trial update describes the STRONG program, which uses remote observation and nutrition guidance to support gastroesophageal cance…
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CLINICAL_TRIALS research · 2025-10-29Clinical Trial Update: Neratinib and Fam-Trastuzumab Deruxtecan in Advanced Gastro-esophageal Cancer Patients [Phase 1]
A Phase 1 clinical trial evaluating the combination of neratinib and fam-trastuzumab deruxtecan for advanced gastric and gastroesophageal ca…
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: ASKB589 in Combination With CAPOX and PD-1 Inhibitors in Patients With Advanced, and Unresectable G/GEJ Cancer. [Phase 1, Phase 2]
The document summarizes a Phase 1/Phase 2 clinical trial evaluating ASKB589 in combination with CAPOX chemotherapy and PD-1 inhibitors for p…
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: RegoNivo vs Standard of Care Chemotherapy in AGOC [Phase 3]
Phase 3 clinical trial update comparing RegoNivo (regorafenib + nivolumab) against standard-of-care chemotherapy in gastroesophageal cancer;…
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CLINICAL_TRIALS research · 2025-07-16Clinical Trial Update: Study of SBRT/Olaparib Followed by Pembrolizumab/Olaparib in Gastric Cancers [Phase 2]
A Phase 2 clinical trial evaluating SBRT/Olaparib followed by Pembrolizumab/Olaparib in gastric and gastroesophageal cancers; currently acti…
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CLINICAL_TRIALS research · 2025-06-10Clinical Trial Update: Add-Aspirin: A Trial Assessing the Effects of Aspirin on Disease Recurrence and Survival After Primary Therapy in Common Non Metastatic Solid Tumours [Phase 3]
This entry describes the Add-Aspirin Phase 3 trial evaluating whether adding aspirin after primary therapy reduces recurrence and improves s…
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: Peri-operative Treatment of Resectable Gastroesophageal Cancer Using Bemarituzumab (BEMA) Plus Perioperative Treatment [Phase 1]
Phase 1 trial update evaluating peri-operative treatment of resectable gastroesophageal cancer with bemarituzumab (BEMA) plus perioperative …
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Feasibility and Effect of Resistance Training and Protein Supplementation in Patients With Advanced Gastroesophageal Cancer [NA]
This clinical trial update assesses the feasibility and potential effects of resistance training and protein supplementation in patients wit…
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CLINICAL_TRIALS research · 2025-05-11Clinical Trial Update: First Line gastroeSOphageal metastatiC canceR primAry and disTant (if Oligometastatic) lEsions-directed Radiotherapy, a Multicentric, Phase III, Randomized Controlled Trial [NA]
A multicenter Phase III randomized trial evaluating first-line radiotherapy directed at both primary and distant gastroesophageal cancer les…
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CLINICAL_TRIALS research · 2025-02-12Clinical Trial Update: Epidemiological Characteristics of Gastric and Pancreatic Cancers in Latin America
This clinical trial update reports epidemiological characteristics of gastric, gastroesophageal, and pancreatic cancers in Latin America; th…
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CLINICAL_TRIALS research · 2025-01-10Clinical Trial Update: A Value-Driven Study on Reducing Immune Checkpoint Inhibitor Dosing Frequency in Advanced Cancers [Phase 2]
This Phase 2 trial aims to evaluate whether reducing the dosing frequency of immune checkpoint inhibitors is feasible across advanced cancer…
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CLINICAL_TRIALS research · 2024-11-12Clinical Trial Update: Developing ctDNA Guided Adjuvant Therapy for Gastrooesophageal Cancer [Phase 2]
A Phase 2 trial from the University of Southampton is exploring ctDNA-guided adjuvant therapy for gastroesophageal cancer and is currently r…