Fuchs Endothelial Corneal Dystrophy
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CLINICAL_TRIALS trial_result · 2026-08-07Clinical Trial Results: A Multicenter Study Assessing the Efficacy and Safety of STN1010904 Ophthalmic Suspension 0.03% and 0.1% Compared With Vehicle in Subjects With Fuchs Endothelial Corneal Dystrophy (FECD) [Phase 2]
Phase 2 multicenter trial evaluating STN1010904 ophthalmic suspension (0.03% and 0.1%) versus vehicle in Fuchs Endothelial Corneal Dystrophy…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Effect of Descemet Membrane Polishing in Fuchs Endothelial Corneal Dystrophy [NA]
This clinical trial update notes a study evaluating Descemet membrane polishing in Fuchs endothelial corneal dystrophy, with status NOT_YET_…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: AURN001 Efficacy in Participants With Corneal Edema Secondary to Corneal Endothelial Dysfunction [Phase 3]
Phase 3 trial update for Aurion Biotech's AURN001 in corneal edema due to corneal endothelial dysfunction, currently recruiting.
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: The Belgian Endothelial Surgical Transplant of the Cornea [NA]
Clinical trial update for a Belgian endothelial corneal transplant. The study at University Hospital Antwerp is currently recruiting patient…
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CLINICAL_TRIALS trial_result · 2026-03-23Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of K-321 Eye Drops After Descemetorhexis in Participants With Fuchs Endothelial Corneal Dystrophy (FECD) [Phase 3]
A Phase 3 trial evaluating safety and efficacy of K-321 Eye Drops after Descemetorhexis in Fuchs Endothelial Corneal Dystrophy has completed…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Partial Range Of Field IOLs in DMEK-Enabled Procedures [NA]
A clinical trial update describing the evaluation of partial range of field intraocular lenses in DMEK-enabled procedures for cataract and F…
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CLINICAL_TRIALS withdrawal · 2026-03-02Clinical Trial Update: Assessment of Corneal Endothelial Function Following Hypoxic Stress [Phase 1, Phase 2]
A clinical trial assessing corneal endothelial function after hypoxic stress in Fuchs' Endothelial Corneal Dystrophy was withdrawn (Phase 1/…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Effect of Donor Diabetes and Other Factors on Corneal Transplant Endothelial Cell Loss and Success at 5 Years [NA]
A clinical trial update describing a study on how donor diabetes and other factors affect corneal transplant endothelial cell loss and graft…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Developing a Nationwide Registry to Track Longitudinal Clinical Outcomes of Corneal Surgery and Disease
A nationwide registry is being developed to track longitudinal clinical outcomes after corneal surgery and in corneal disease, including gra…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Influence of Supine Positioning on the Outcomes After Descemet Membrane Endothelial Keratoplasty (DMEK) [NA]
A clinical trial update examining whether supine positioning affects outcomes after Descemet Membrane Endothelial Keratoplasty in Fuchs Endo…
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: A Study to Investigate the Safety and Efficacy of K-321 Eye Drops After Simultaneous Cataract Surgery and Descemetorhexis in Participants With Fuchs Endothelial Corneal Dystrophy (FECD) [Phase 3]
A Phase 3 study evaluating the safety and efficacy of K-321 Eye Drops after cataract surgery in Fuchs Endothelial Corneal Dystrophy has comp…
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: DT-168 in Keratoplasty Patients With Fuchs Endothelial Corneal Dystrophy [Phase 2]
A Phase 2 clinical trial evaluating DT-168 in keratoplasty patients with Fuchs Endothelial Corneal Dystrophy is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Descemet Endothelial Thickness Comparison Trial II [Phase 3]
Sponsored by Stanford University, this Phase 3 trial called Descemet Endothelial Thickness Comparison Trial II is investigating treatment st…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Descemet Endothelial Thickness Comparison Trial I [Phase 3]
A Phase 3 clinical trial update for the Descemet Endothelial Thickness Comparison Trial I investigating Fuchs endothelial corneal dystrophy;…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Study to Assess Safety and Tolerability of Multiple Doses of EO2002 [Phase 1]
Phase 1 study to assess safety and tolerability of multiple doses of EO2002 in patients with corneal edema and related endothelial diseases;…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: DMEK Endothelial Keratoplasty in Patients With a History of Anterior or Posterior Segment Surgery
A clinical trial evaluating DMEK endothelial keratoplasty in patients with a history of anterior or posterior segment eye surgery is current…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: SUCCESS Score Validation in Fuchs Dystrophy
A clinical study named SUCCESS Score Validation in Fuchs Endothelial Corneal Dystrophy is currently recruiting to validate a scoring system …
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CLINICAL_TRIALS research · 2025-09-29Clinical Trial Update: Targeting Reactive Oxygen Species Production as a Novel Therapeutic in Fuch's Endothelial Corneal Dystrophy [Phase 2]
A Phase 2 clinical trial is investigating a novel therapy that targets reactive oxygen species production for Fuchs Endothelial Corneal Dyst…
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CLINICAL_TRIALS research · 2025-09-12Clinical Trial Update: Safety and Efficacy of Tissue Engineered Endothelial Keratoplasty [Phase 1]
Phase 1 clinical trial evaluating the safety and efficacy of a tissue-engineered endothelial keratoplasty for corneal endothelial decompensa…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: OCT in Fuchs' Dystrophy
A clinical trial sponsored by Oregon Health and Science University is recruiting to study the use of optical coherence tomography (OCT) in F…
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: Prevalence of Fuchs Endothelial Corneal Dystrophy in a Population of Dermatology Patients.
A completed clinical trial update reports on the prevalence of Fuchs Endothelial Corneal Dystrophy in a population of dermatology patients.
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CLINICAL_TRIALS trial_result · 2025-07-15Clinical Trial Update: A Multicenter Study Assessing the Efficacy and Safety of STN1010904 Ophthalmic Suspension 0.03% and 0.1% Compared With Vehicle in Subjects With Fuchs Endothelial Corneal Dystrophy (FECD) [Phase 2]
A Phase 2 multicenter study evaluating STN1010904 ophthalmic suspension (0.03% and 0.1%) versus vehicle in Fuchs Endothelial Corneal Dystrop…
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: DISCOVER Study: Microscope-integrated Intraoperative OCT Study
The DISCOVER trial from The Cleveland Clinic is evaluating microscope-integrated intraoperative OCT in retinal surgery and is currently recr…
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CLINICAL_TRIALS research · 2025-06-17Clinical Trial Update: Comparison of Outcomes Between Femtosecond Laser-Assisted and Conventional Phacoemulsification in Fuchs Endothelial Corneal Dystrophy Patients With Cataracts
This clinical trial compares outcomes of femtosecond laser-assisted cataract surgery with conventional phacoemulsification in patients with …
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: The Effect of Topical Rho-kinase Inhibitors on Corneas of Patients With Fuchs Endothelial Corneal Dystrophy
A clinical trial update examining the effects of topical Rho-kinase inhibitors on the cornea of patients with Fuchs Endothelial Corneal Dyst…