Fuchs Endothelial Corneal Dystrophy
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CLINICAL_TRIALS trial_result · 2025-04-01Clinical Trial Update: A Comparison of Visual Functions and Side-effects After DSAEK or DMEK for Fuchs' Endothelial Dystrophy [NA]
A clinical trial comparing visual function and side effects after DSAEK versus DMEK for Fuchs' endothelial corneal dystrophy; the study is c…
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CLINICAL_TRIALS research · 2025-03-18Clinical Trial Update: FECD-TRACE: Fuchs' Endothelial Corneal Dystrophy TRAjectory and Correlation With Genotype in the United Kingdom
A UK-based clinical trial (FECD-TRACE) at University College London studying the trajectory of Fuchs endothelial corneal dystrophy and its c…
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CLINICAL_TRIALS trial_result · 2025-03-05Clinical Trial Update: Study of Safety and Tolerability of EO2002 in the Treatment of Corneal Edema [Phase 1]
This Phase 1 study evaluated the safety and tolerability of EO2002 for corneal edema and related endothelial disorders; the trial has comple…
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CLINICAL_TRIALS research · 2025-03-05Clinical Trial Update: Prognosis of Posterior Lamellar Keratoplasty, an Observational Cohort Study
An observational cohort study evaluating prognosis after posterior lamellar keratoplasty is currently recruiting, studying Fuchs' Endothelia…
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CLINICAL_TRIALS research · 2025-02-21Clinical Trial Update: Trial Comparing Cataract Surgery With Triple-DMEK in Patients With Cataract and Fuchs Endothelial Corneal Dystrophy [NA]
A clinical trial is recruiting to compare cataract surgery with triple-DMEK in patients who have cataract and Fuchs endothelial corneal dyst…
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CLINICAL_TRIALS trial_result · 2024-11-05Clinical Trial Update: Study to Investigate the Safety and Efficacy of K-321 in Patients With Fuchs Endothelial Corneal Dystrophy (FECD) Following Descemetorhexis [Phase 2]
Phase 2 study of K-321 for Fuchs' Endothelial Corneal Dystrophy following Descemetorhexis has completed, with results posted on 2024-11-05.
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CLINICAL_TRIALS trial_result · 2024-10-01Clinical Trial Update: Association Between Fuchs' Endothelial Corneal Dystrophy Severity and Estrogen Exposure
A completed clinical trial assessing whether estrogen exposure is associated with the severity of Fuchs endothelial corneal dystrophy.
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CLINICAL_TRIALS research · 2024-08-09Clinical Trial Update: Analysis of the Genotype/Phenotype Relationship in the Fuchs' Corneal Endothelial Dystrophy in France
A France-based clinical trial is investigating the genotype-phenotype relationship in Fuchs endothelial corneal dystrophy and is currently r…
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CLINICAL_TRIALS trial_result · 2024-07-01Clinical Trial Update: Novel Diagnostics With Optical Coherence Tomography: Imaging the Anterior Eye
The document reports a clinical trial update on novel diagnostic methods using optical coherence tomography to image the anterior segment of…
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CLINICAL_TRIALS trial_result · 2023-10-30Clinical Trial Update: A Phase 1/ Phase 2 Study of TTHX1114(NM141) [Phase 1, Phase 2]
Phase 1/2 trial update for TTHX1114 (NM141) in corneal endothelial dystrophies, including Fuchs endothelial corneal dystrophy; trial complet…
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CLINICAL_TRIALS trial_result · 2022-09-01Clinical Trial Update: A Phase 2 Study Evaluating the Safety and Efficacy of Netarsudil Ophthalmic Solution in Patients With Corneal Edema Due to Fuchs Corneal Dystrophy [Phase 2]
Phase 2 study evaluating safety and efficacy of Netarsudil ophthalmic solution for corneal edema due to Fuchs corneal dystrophy has complete…
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CLINICAL_TRIALS trial_result · 2019-01-23Clinical Trial Update: Study of Endothelial Keratoplasty Outcomes [NA]
This clinical trial update reports the completed study evaluating outcomes of endothelial keratoplasty for Fuchs' Endothelial Corneal Dystro…
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CLINICAL_TRIALS research · 2018-07-12Clinical Trial Update: Ripasudil 0.4% Eye Drops in Fuchs Endothelial Corneal Dystrophy [Phase 2]
Phase 2 clinical trial evaluating ripasudil 0.4% eye drops for Fuchs' Endothelial Corneal Dystrophy; current status is unknown.
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CLINICAL_TRIALS research · 2018-05-24Clinical Trial Update: The Molecular Pathogenesis of Late-onset Fuchs' Endothelial Corneal Dystrophy
This trial update reports on a study examining the molecular mechanisms underlying late-onset Fuchs endothelial corneal dystrophy.
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CLINICAL_TRIALS trial_result · 2017-03-13Clinical Trial Update: Using the Optovue OCT to Select IOL Power
The trial evaluating use of Optovue OCT to select intraocular lens power for patients with Fuchs' endothelial corneal dystrophy and cataract…
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CLINICAL_TRIALS trial_result · 2016-10-10Clinical Trial Update: Comparison of Two Techniques in Achieving Corneal Graft [NA]
Completed clinical trial comparing two surgical techniques for achieving a corneal graft in Fuchs endothelial corneal dystrophy.
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CLINICAL_TRIALS withdrawal · 2016-09-27Clinical Trial Update: Study of the Effect of Aspheric Lenses in Patients With Fuch's Dystrophy [NA]
The clinical trial evaluating the effect of aspheric lenses in patients with Fuchs endothelial corneal dystrophy has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-09-15Clinical Trial Update: Impact of Graft Thickness on Visual Gain After Descemet's Stripping Automated Endothelial Keratoplasty
A completed clinical trial evaluating whether graft thickness affects the visual gain after Descemet's Stripping Automated Endothelial Kerat…
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CLINICAL_TRIALS trial_result · 2016-08-11Clinical Trial Update: Fuchs' Endothelial Dystrophy: Clinical Characteristics, Treatment Outcome, and Pathology [NA]
This completed clinical trial report summarizes clinical characteristics, treatment outcomes, and pathology of Fuchs' Endothelial Corneal Dy…
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CLINICAL_TRIALS trial_result · 2015-08-21Clinical Trial Update: Combined Cataract Surgery and Planned Descemetorhexis [NA]
Completed clinical trial evaluating combined cataract surgery with planned Descemetorhexis in patients with Fuchs' endothelial corneal dystr…
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CLINICAL_TRIALS trial_result · 2015-04-30Clinical Trial Update: Comparison of Corticosteroid Dosing Regimens After Endothelial Keratoplasty [Phase 4]
This Phase 4 trial update compares different corticosteroid dosing regimens after endothelial keratoplasty to assess safety and efficacy.
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CLINICAL_TRIALS withdrawal · 2014-05-02Clinical Trial Update: Topical Steroid Treatment After Posterior Lamellar Corneal Transplantation [NA]
The clinical trial evaluating topical steroid treatment after posterior lamellar corneal transplantation has been withdrawn. Sponsor: Aarhus…
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CLINICAL_TRIALS trial_result · 2013-12-24Clinical Trial Update: Outcome After Descemet Membrane Endothelial Keratoplasty (DMEK) and Ultra-thin Descemet Stripping Automated Endothelial Keratoplasty (DSAEK) [NA]
Clinical trial update describing outcomes after Descemet Membrane Endothelial Keratoplasty (DMEK) and ultra-thin Descemet stripping automate…
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CLINICAL_TRIALS research · 2013-02-15Clinical Trial Update: Comparing Endoglide to Endoserter for DSAEK Graft Insertion [NA]
A clinical trial update comparing Endoglide to Endoserter for Descemet Stripping Automated Endothelial Keratoplasty graft insertion, with sp…
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CLINICAL_TRIALS trial_result · 2011-01-27Clinical Trial Update: Study Comparing Tan EndoGlide With the Busin Glide for Insertion of the Donor Graft in DSAEK [NA]
This clinical trial update compares two donor graft insertion devices, Tan EndoGlide and Busin Glide, in Descemet stripping automated endoth…