Fragile Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-07-16Clinical Trial Update: Sertraline vs. Placebo in the Treatment of Anxiety in Children and AdoLescents With NeurodevelopMental Disorders [Phase 2]
A Phase 2 trial is evaluating sertraline versus placebo for anxiety in children and adolescents with neurodevelopmental disorders, including…
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: Tracking Early Emergence of Sound Perception Impairments in FXS With Multimodal fNIRS/EEG-Preschool Age [NA]
A ClinicalTrials.gov entry describes a preschool-age study in Fragile X syndrome using multimodal fNIRS and EEG to track early sound percept…
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CLINICAL_TRIALS trial_result · 2025-05-04Clinical Trial Update: Neural Biomarkers in Fragile X Syndrome
A completed clinical trial by Connecta Therapeutics investigating neural biomarkers in Fragile X syndrome.
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: Early Check: Expanded Screening in Newborns
An update on an ongoing clinical trial (NCT03655223) evaluating expanded newborn screening under the Early Check program, with enrollment by…
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CLINICAL_TRIALS research · 2025-02-18Clinical Trial Update: Metformin in Children With Fragile X Syndrome [Phase 4]
Phase 4 clinical trial update shows a study evaluating metformin in children with Fragile X syndrome is currently recruiting. The sponsor is…
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CLINICAL_TRIALS research · 2025-02-17Clinical Trial Update: Effect of CBD on the Brain [Phase 2]
A Phase 2 clinical trial led by Université de Sherbrooke is evaluating the effects of cannabidiol (CBD) on brain function in Fragile X syndr…
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CLINICAL_TRIALS research · 2025-02-17Clinical Trial Update: Effect of CANnabidiol on Anxiety and GABAergic Function in Individuals with Fragile-X Syndrome [Phase 2]
A Phase 2 clinical trial evaluating CANn cannabidiol's effects on anxiety and GABAergic function in individuals with Fragile X syndrome, cur…
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: CTH120 First-in-Human Study: Single and Multiple Ascending Doses and Potential Food Interaction [Phase 1]
Connecta Therapeutics reports the completion of its first-in-human Phase 1 study of CTH120 in Fragile X Syndrome, evaluating single and mult…
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CLINICAL_TRIALS trial_result · 2025-01-17Clinical Trial Update: A Trial of Metformin in Individuals With Fragile X Syndrome [Phase 2, Phase 3]
The document reports the completion of a Phase 2/Phase 3 clinical trial evaluating metformin in individuals with Fragile X syndrome.
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CLINICAL_TRIALS trial_result · 2025-01-14Clinical Trial Update: Study of SPG601 in Adult Men With Fragile X Syndrome [Phase 2]
A Phase 2 study of SPG601 in adult men with Fragile X Syndrome has completed.
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CLINICAL_TRIALS trial_result · 2024-12-19Clinical Trial Update: A 2-Period Crossover Study of BPN14770 in Adults Males With Fragile X Syndrome [Phase 2]
A Phase 2 two-period crossover trial of BPN14770 in adult males with Fragile X Syndrome has completed and results have been posted.
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CLINICAL_TRIALS research · 2024-11-08Clinical Trial Update: Group CBT in Adolescents With Fragile X Syndrome and in Adolescents With Autism Spectrum Disorder [NA]
This ClinicalTrials.gov update describes a study evaluating group cognitive-behavioral therapy for adolescents with Fragile X syndrome and a…
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CLINICAL_TRIALS trial_result · 2024-10-08Clinical Trial Update: Protein Synthesis in the Brain of Patients With Fragile X Syndrome
A completed clinical trial investigated protein synthesis in the brain of patients with Fragile X Syndrome, with healthy volunteers also par…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: ERG/5-HTP in Fragile X Syndrome (FXS) [Phase 2]
Phase 2 trial update for ERG/5-HTP in Fragile X Syndrome reports completed results with findings posted on 2024-09-19.
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CLINICAL_TRIALS research · 2024-06-03Clinical Trial Update: Probiotic Intervention for Microbiome Modifications and Clinical Improvements in Fragile X Syndrome [NA]
A clinical trial is recruiting to evaluate whether a probiotic intervention can modify the microbiome and improve clinical outcomes in Fragi…
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: An Investigation of Psilocybin on Behavioural and Cognitive Symptoms of Adults With Fragile X Syndrome [Phase 2]
Phase 2 clinical trial evaluating psilocybin for behavioral and cognitive symptoms in adults with Fragile X syndrome has been suspended.
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CLINICAL_TRIALS trial_result · 2024-01-23Clinical Trial Update: A Study of OV101 in Individuals With Fragile X Syndrome [Phase 2]
Phase 2 clinical trial of OV101 in Fragile X Syndrome has completed and results were posted in 2024.
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CLINICAL_TRIALS trial_result · 2023-11-09Clinical Trial Update: Effects of Social Gaze Training on Brain and Behavior in Fragile X Syndrome [Phase 1, Phase 2]
A clinical trial evaluating social gaze training on brain and behavior in Fragile X Syndrome (Phase 1/Phase 2) has completed recruitment.
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CLINICAL_TRIALS trial_result · 2023-10-10Clinical Trial Update: AFQ056 for Language Learning in Children With FXS [Phase 2]
Phase 2 trial update for AFQ056 in language learning in children with Fragile X Syndrome has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-04-10Clinical Trial Update: Ganaxolone Treatment in Children With Fragile X Syndrome [Phase 2]
Phase 2 clinical trial update on ganaxolone for Fragile X Syndrome in children; results posted after completion.
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CLINICAL_TRIALS trial_result · 2022-07-22Clinical Trial Update: Clinical Trial for Asses the Safety and Efficacy of Vitamin C and Vitamin E in Combination Versus Placebo for Treating Cognitive and Behavior Disorder in Children With Fragile X Syndrome [Phase 3]
Phase 3 clinical trial evaluating vitamin C and vitamin E combination vs placebo for cognitive and behavioral disorders in children with Fra…
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CLINICAL_TRIALS research · 2022-06-16Clinical Trial Update: Clinical Study Of caNNabidiol in childrEn and adolesCenTs With Fragile X (CONNECT-FX) [Phase 2, Phase 3]
Clinical study of cannabidiol in children and adolescents with Fragile X Syndrome has completed Phase 2/3 with results posted.
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CLINICAL_TRIALS trial_result · 2021-11-24Clinical Trial Update: Neurophysiological and Acute Pharmacological Studies in FXS Patients [EARLY_Phase 1]
Early-phase trial exploring neurophysiological and acute pharmacological effects in Fragile X Syndrome; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-02-04Clinical Trial Update: Metformin in Children and Adults With Fragile X Syndrome [Phase 2]
Phase 2 clinical trial investigating metformin in children and adults with Fragile X Syndrome has completed.
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CLINICAL_TRIALS trial_result · 2020-12-23Clinical Trial Update: Safety and Efficacy of AFQ056 in Adult Patients With Fragile X Syndrome [Phase 2]
Phase 2 clinical trial update evaluating safety and efficacy of AFQ056 in adults with Fragile X Syndrome.