Fragile Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Development of Non-Invasive Prenatal Diagnosis for Single Gene Disorders
A clinical trial update describes development of non-invasive prenatal diagnosis for single-gene disorders. The study, based in Paris, is cu…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Study of MRM-3379 in Male Participants With Fragile X Syndrome (BLOOM) [Phase 2]
A Phase 2 clinical trial (BLOOM) evaluating MRM-3379 in male participants with Fragile X syndrome is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Optical Imaging in X-linked Disorders. [NA]
A clinical trial in France is updating on an optical imaging study in X-linked disorders and is currently recruiting participants for Fragil…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Alpha Auditory Entrainment for Cognitive Enhancement and Sensory Hypersensitivity in Youth With Developmental Disorders [NA]
A clinical trial is recruiting to evaluate Alpha Auditory Entrainment for cognitive enhancement and sensory hypersensitivity in youth with F…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disorders
Clinical trial update on an intensive multimodal neurorehabilitation program aimed at enhancing neuroplasticity in pediatric neurodevelopmen…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Tracking Early Emergence of Sound Perception Impairments in FXS With Multimodal fNIRS/EEG- Infant [NA]
A clinical trial recruiting infants with Fragile X Syndrome to study early sound perception impairments using multimodal fNIRS and EEG.
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Speech-in-noise Perception in Autism and Fragile X [NA]
A recruiting clinical trial investigating how individuals with autism spectrum disorder and fragile X syndrome perceive speech in noisy envi…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: The Psychiatric and Cognitive Phenotypes in Velocardiofacial Syndrome [Phase 4]
An ongoing Phase 4 clinical study led by The Chaim Sheba Medical Center is examining psychiatric and cognitive phenotypes in 22q11.2 deletio…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: The Neurocognitive Bases of Trust in Intellectual Disability
A clinical trial update describing research into the neurocognitive bases of trust in individuals with intellectual disability, focusing on …
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Physical Activity and Community EmPOWERment Project [NA]
Clinical trial update from the University of North Carolina on the Physical Activity and Community Empowerment project. The study is current…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Web Intervention for Parents of Youth With Genetic Syndromes (WINGS) [NA]
Rush University Medical Center is conducting a web-based intervention (WINGS) for parents of youths with several genetic syndromes, and the …
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Inhibition of Aggressive Behavior in Participants With Fragile X Syndrome [Phase 2]
A Phase 2 trial from Azevan Pharmaceuticals aims to inhibit aggressive behavior in people with Fragile X syndrome, but the study is not yet …
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Evaluating the Neurophysiologic and Clinical Effects of Single Dose Drug Challenge [Phase 2]
Phase 2 clinical trial evaluating the neurophysiologic and clinical effects of a single-dose drug challenge in Fragile X Syndrome; the study…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Sensitivity of the NIH Toolbox to Stimulant Treatment in Intellectual Disabilities [Phase 1]
Phase 1 clinical trial update evaluating how sensitive the NIH Toolbox is to stimulant treatment in individuals with intellectual disabiliti…
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: An Open-Label Extension Study of BPN14770 in Subjects With Fragile X Syndrome [Phase 3]
An open-label extension study of BPN14770 for Fragile X Syndrome is ongoing in Phase 3 and is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: Parent and Infant Inter(X)Action Intervention (PIXI) [NA]
Clinical trial update for the PIXI Inter(X)Action Intervention (NCT03836300), currently enrolling by invitation across Fragile X Syndrome, A…
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CLINICAL_TRIALS research · 2025-07-16Clinical Trial Update: Sertraline vs. Placebo in the Treatment of Anxiety in Children and AdoLescents With NeurodevelopMental Disorders [Phase 2]
A Phase 2 trial is evaluating sertraline versus placebo for anxiety in children and adolescents with neurodevelopmental disorders, including…
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: Tracking Early Emergence of Sound Perception Impairments in FXS With Multimodal fNIRS/EEG-Preschool Age [NA]
A ClinicalTrials.gov entry describes a preschool-age study in Fragile X syndrome using multimodal fNIRS and EEG to track early sound percept…
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: Early Check: Expanded Screening in Newborns
An update on an ongoing clinical trial (NCT03655223) evaluating expanded newborn screening under the Early Check program, with enrollment by…
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CLINICAL_TRIALS research · 2025-02-18Clinical Trial Update: Metformin in Children With Fragile X Syndrome [Phase 4]
Phase 4 clinical trial update shows a study evaluating metformin in children with Fragile X syndrome is currently recruiting. The sponsor is…
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CLINICAL_TRIALS research · 2025-02-17Clinical Trial Update: Effect of CBD on the Brain [Phase 2]
A Phase 2 clinical trial led by Université de Sherbrooke is evaluating the effects of cannabidiol (CBD) on brain function in Fragile X syndr…
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CLINICAL_TRIALS research · 2025-02-17Clinical Trial Update: Effect of CANnabidiol on Anxiety and GABAergic Function in Individuals with Fragile-X Syndrome [Phase 2]
A Phase 2 clinical trial evaluating CANn cannabidiol's effects on anxiety and GABAergic function in individuals with Fragile X syndrome, cur…
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CLINICAL_TRIALS research · 2024-11-08Clinical Trial Update: Group CBT in Adolescents With Fragile X Syndrome and in Adolescents With Autism Spectrum Disorder [NA]
This ClinicalTrials.gov update describes a study evaluating group cognitive-behavioral therapy for adolescents with Fragile X syndrome and a…
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CLINICAL_TRIALS research · 2024-06-03Clinical Trial Update: Probiotic Intervention for Microbiome Modifications and Clinical Improvements in Fragile X Syndrome [NA]
A clinical trial is recruiting to evaluate whether a probiotic intervention can modify the microbiome and improve clinical outcomes in Fragi…
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: An Investigation of Psilocybin on Behavioural and Cognitive Symptoms of Adults With Fragile X Syndrome [Phase 2]
Phase 2 clinical trial evaluating psilocybin for behavioral and cognitive symptoms in adults with Fragile X syndrome has been suspended.