Fragile Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-10-31Clinical Trial Update: Metformin in Patients With Fragile X [Phase 1, Phase 2]
A clinical trial update for metformin in Fragile X Syndrome spanning Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2019-09-11Clinical Trial Update: Combining Lovastatin and a Parent-Implemented Language Intervention for Fragile X Syndrome [Phase 4]
Phase 4 clinical trial evaluating the combination of Lovastatin with a parent-implemented language intervention for Fragile X Syndrome has c…
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CLINICAL_TRIALS trial_result · 2019-05-10Clinical Trial Update: "Using Epigallocatechin Gallate (EGCG) and Cognitive Training to Modulate Cognitive Performance in Patients With Fragile X Syndrome" (TESFX) [Phase 2]
Phase 2 trial investigating epigallocatechin gallate (EGCG) with cognitive training to modulate cognitive performance in Fragile X Syndrome …
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CLINICAL_TRIALS trial_result · 2018-10-15Clinical Trial Update: Combined Treatment of Minocycline and Lovastatin to Treat Individuals With Fragile X Syndrome [Phase 2]
Phase 2 clinical trial evaluating combined minocycline and lovastatin for Fragile X syndrome has been completed.
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CLINICAL_TRIALS trial_result · 2018-02-05Clinical Trial Update: A Safety Study of NNZ-2566 in Patients With Fragile X Syndrome [Phase 2]
Phase 2 safety study of NNZ-2566 in Fragile X Syndrome completed.
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CLINICAL_TRIALS trial_result · 2017-11-30Clinical Trial Update: Single Dose Pharmacokinetic (PK) Study [Phase 1]
Healx AI completed a Phase 1 single-dose pharmacokinetic study evaluating an investigational therapy for Angelman Syndrome and Fragile X Syn…
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CLINICAL_TRIALS trial_result · 2017-10-06Clinical Trial Update: The Natural History of Reproductive and Overall Health in Girls and Women With a Pre-Mutation in the FMR1 Gene; Creation of a Patient Registry
The study reports on the natural history of reproductive and overall health in girls and women with an FMR1 premutation and describes the cr…
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CLINICAL_TRIALS trial_result · 2017-09-25Clinical Trial Update: Trial of Sertraline to Treat Children With Fragile X Syndrome [Phase 2]
Phase 2 trial evaluating sertraline for children with Fragile X Syndrome has completed with results posted.
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CLINICAL_TRIALS trial_result · 2017-04-28Clinical Trial Update: Acamprosate in Youth With Fragile X Syndrome [Phase 2]
Phase 2 trial of acamprosate in youth with Fragile X Syndrome and autism spectrum disorders has completed with results posted.
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CLINICAL_TRIALS trial_result · 2017-04-18Clinical Trial Update: A Prospective Open-label Study of Aripiprazole in Fragile X Syndrome [Phase 2]
This release summarizes results from a Phase 2 open-label study of aripiprazole in Fragile X Syndrome.
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CLINICAL_TRIALS trial_result · 2017-04-18Clinical Trial Update: Riluzole in Fragile X Syndrome [Phase 4]
Phase 4 clinical trial evaluating riluzole for Fragile X syndrome has completed and posted results.
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CLINICAL_TRIALS trial_result · 2017-01-06Clinical Trial Update: A PET Brain Imaging Study of mGluR5 in Subjects With Neuropsychiatric Conditions [Phase 1]
Phase 1 PET imaging study of an mGluR5 tracer across several neuropsychiatric conditions has been completed.
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: A Study With RO4917523 in Patients With Fragile X Syndrome [Phase 2]
A Phase 2 study of RO4917523 in Fragile X Syndrome has completed, sponsored by Hoffmann-La Roche.
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CLINICAL_TRIALS trial_result · 2016-08-11Clinical Trial Update: A Study of RO4917523 in Pediatric Patients With Fragile X Syndrome [Phase 2]
A Phase 2 clinical trial of RO4917523 in pediatric patients with Fragile X syndrome has completed.
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CLINICAL_TRIALS trial_result · 2016-07-11Clinical Trial Update: A Study of RO4917523 in Patients With Fragile X Syndrome [Phase 2]
Phase 2 study of RO4917523 in Fragile X Syndrome has completed.
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CLINICAL_TRIALS trial_result · 2016-07-06Clinical Trial Update: A 6-week, Study of MG01CI Low Dose and High Dose Compared With Placebo in Adults and Adolescents With Fragile X Syndrome [Phase 2]
Phase 2 randomized evaluation of MG01CI at low and high doses versus placebo was conducted in adults and adolescents with Fragile X Syndrome…
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CLINICAL_TRIALS trial_result · 2016-05-25Clinical Trial Update: Long-term, Safety, Tolerability and Efficacy Study of AFQ056 in Adult Patients With Fragile X Syndrome [Phase 2]
This update reports the termination of a Phase 2 long-term safety, tolerability and efficacy study of AFQ056 (mavoglurant) in adults with Fr…
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CLINICAL_TRIALS trial_result · 2016-04-18Clinical Trial Update: Brain Connectivity in Neurodevelopmental Disorders in Response to Treatment
A completed clinical trial update examining how treatment affects brain connectivity in autism spectrum disorder, Fragile X syndrome, and ps…
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CLINICAL_TRIALS trial_result · 2016-03-17Clinical Trial Update: Randomized Controlled Study of Donepezil in Fragile X Syndrome [Phase 2]
A Phase 2 randomized controlled trial evaluating donepezil in Fragile X Syndrome has completed, with results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-02-18Clinical Trial Update: Add-on Pilot Trial of Minocycline to Treat Fragile X Syndrome [NA]
This document reports an add-on pilot trial of minocycline to treat Fragile X Syndrome. The study was completed and results were posted on 2…
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CLINICAL_TRIALS trial_result · 2015-10-12Clinical Trial Update: Long-term, Safety and Tolerability Study of AFQ056 in Adolescent Patients With Fragile X Syndrome (Open-label) [Phase 2, Phase 3]
An open-label long-term safety and tolerability study of mavoglurant (AFQ056) in adolescents with Fragile X Syndrome was terminated, with re…
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CLINICAL_TRIALS trial_result · 2015-05-12Clinical Trial Update: Safety and Efficacy of AFQ056 in Adolescent Patients With Fragile X Syndrome [Phase 2]
Phase 2 trial evaluated AFQ056 (mavoglurant) for safety and efficacy in adolescents with Fragile X syndrome; results were posted in 2015 aft…
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CLINICAL_TRIALS trial_result · 2015-04-14Clinical Trial Update: Safety and Efficacy Study of Antioxidants for the Treatment of the Fragile X Syndrome [Phase 2]
Phase 2 safety and efficacy study of antioxidants for Fragile X syndrome has completed.
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CLINICAL_TRIALS trial_result · 2014-08-29Clinical Trial Update: Double-blind Placebo Controlled Study of Oxytocin in Fragile X Syndrome [Phase 2]
Phase 2 double-blind, placebo-controlled trial of oxytocin in Fragile X Syndrome completed with posted results.
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CLINICAL_TRIALS trial_result · 2014-07-30Clinical Trial Update: Trial of Minocycline to Treat Children With Fragile X Syndrome [NA]
The clinical trial testing minocycline in children with Fragile X Syndrome has completed and posted results.