Extensive-stage Small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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EMA approval · 2026-03-27New treatment for relapsed extensive-stage small cell lung cancer
The European Medicines Agency announces Imdylltra as a new treatment for relapsed extensive-stage small cell lung cancer, addressing an unme…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Iadademstat + SBRT With Atezo in ES-SCLC [Phase 1]
Phase 1 study evaluating iadademstat in combination with SBRT and atezolizumab for extensive-stage small cell lung cancer; recruitment is on…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Study of Tarlatamab in Combination With AB248 in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-311) [Phase 1]
Phase 1 clinical trial evaluating Tarlatamab in combination with AB248 for extensive-stage small cell lung cancer; recruitment is ongoing.
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Carboplatin/Cisplatin + Etoposide + Benmelstobart Sequential Benmelstobart Combined With Anlotinib Versus Carboplatin/Cisplatin + Etoposide + Tislelizumab Sequential Tislelizumab in the Treatment of Extensive Stage Small Cell Lung Cancer [Phase 2]
Phase 2 trial in extensive-stage small cell lung cancer comparing sequential Benmelstobart with Anlotinib to sequential Tislelizumab followi…
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: Study of Sacituzumab Govitecan Versus Standard of Care in Participants With Previously Treated Extensive Stage Small Cell Lung Cancer [Phase 3]
A Phase 3 study evaluating sacituzumab govitecan versus standard of care for previously treated extensive-stage small cell lung cancer is cu…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: A Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed ES-SCLC Patients in Combination With Carboplatin, Etoposide and Atezolizumab [Phase 1, Phase 2]
Clinical trial update on a Phase 1/2 study evaluating [177Lu]Lu-DOTA-TATE in combination with carboplatin, etoposide, and atezolizumab for n…
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CLINICAL_TRIALS trial_result · 2026-03-10Clinical Trial Update: Pembrolizumab and Concurrent Chemoradiotherapy or Radiation Therapy in Treating Patients With Small Cell Lung Cancer [Phase 1]
This Phase 1 trial update reports results for pembrolizumab combined with concurrent chemoradiotherapy or radiation therapy in small cell lu…
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CLINICAL_TRIALS trial_result · 2026-03-10Clinical Trial Update: A Study of Lurbinectedin in Combination With Durvalumab for the Treatment of Participants With ES-SCLC [Phase 2]
A Phase 2 clinical trial is evaluating the combination of lurbinectedin and durvalumab in participants with extensive-stage small-cell lung …
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: SNB-101 for Treatment of Extensive Stage Small Cell Lung Cancer [Phase 1, Phase 2]
A Phase 1/2 clinical trial of SNB-101 for extensive-stage small cell lung cancer is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Study of ZG006 in Combination With PD-1/PD-L1 Immune Checkpoint Inhibitors as First-Line Standard Therapy in Participants With Extensive Stage Small-Cell Lung Cancer [Phase 1]
A Phase 1 trial evaluating ZG006 in combination with PD-1/PD-L1 inhibitors as first-line therapy for extensive-stage small cell lung cancer.…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Durvalumab and Ablative Radiation in Small Cell Lung Cancer (DARES) [Phase 2]
This entry describes a Phase 2 trial investigating durvalumab with ablative radiation for small-cell lung cancer, currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-03Clinical Trial Update: First-Line Tarlatamab in Combination With Carboplatin, Etoposide, and PD-L1 Inhibitor in Subjects With Extensive Stage Small Cell Lung Cancer (ES-SCLC) [Phase 1]
Phase 1 study evaluating first-line Tarlatamab combined with Carboplatin, Etoposide, and a PD-L1 inhibitor for extensive-stage small cell lu…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Golidocitinib With PD-1 Inhibitors as Maintenance Treatment for Previously Untreated ES-SCLC [Phase 2]
A Phase 2 clinical trial evaluating golidocitinib in combination with PD-1 inhibitors as maintenance therapy for previously untreated extens…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: To Assess the Effectiveness and Safety of Zepzelca in Adult Patients With Extensive Stage Small Cell Lung Cancer (SCLC)
This clinical trial update indicates that the study evaluating the effectiveness and safety of Zepzelca (lurbinectedin) in adults with exten…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Ifinatamab Deruxtecan (I-DXd) in Subjects With Pretreated Extensive-Stage Small Cell Lung Cancer (ES-SCLC) [Phase 2]
Phase 2 clinical trial update on Ifinatamab Deruxtecan (I-DXd) for patients with pretreatment extensive-stage small cell lung cancer (ES-SCL…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Tislelizumab Combined With Chemotherapy Followed by Thoracic Consolidation Radiotherapy in the First-line Treatment of Extensive Stage Small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial evaluating tislelizumab plus chemotherapy followed by thoracic consolidation radiotherapy as first-line treatment f…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Tarlatamab for the Treatment of Extensive Stage Small-cell Lung Cancer [Phase 2]
A Phase 2 clinical trial investigating tarlatamab for extensive-stage small cell lung cancer is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Adaptive SBRT Plus Chemoimmunotherapy for ES-SCLC [Phase 1]
A Phase 1 clinical trial evaluating adaptive SBRT with chemoimmunotherapy for extensive-stage small-cell lung cancer has been suspended.
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CLINICAL_TRIALS trial_result · 2026-02-12Clinical Trial Update: Niraparib, Temozolomide and Atezolizumab in Treating Patients With Advanced Solid Tumors and Extensive-Stage Small Cell Lung Cancer With a Complete or Partial Response to Platinum-Based First-Line Chemotherapy [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study of the triple combination niraparib, temozolomide, and atezolizumab in patients with …
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CLINICAL_TRIALS other · 2026-02-09Clinical Trial Update: A Study of PARG Inhibitor IDE161 in Participants With Advanced Solid Tumors [Phase 1]
Phase 1 study of IDE161, a PARG inhibitor, is recruiting in patients with several solid tumor types including breast, ovarian, and various l…
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: A PHASE I STUDY OF ALPS12 IN PATIENTS WITH EXTENSIVE STAGE SMALL CELL LUNG CANCER [Phase 1]
This entry announces a Phase I clinical trial of ALPS12 for extensive stage small cell lung cancer, which is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as First-Line Induction or Maintenance in Subjects With Extensive Stage-Small Cell Lung Cancer (IDeate-Lung03) [Phase 1, Phase 2]
An early-phase clinical trial evaluating I-DXd in combination with atezolizumab, with or without carboplatin, as first-line induction or mai…
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CLINICAL_TRIALS trial_result · 2026-02-05Clinical Trial Update: Sacituzumab Tirumotecan Plus Anlotinib in Previously Treated ES-SCLC [Phase 2]
A Phase 2 clinical trial is evaluating the combination of Sacituzumab Govitecan and Anlotinib in previously treated extensive-stage small ce…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: A Study of Bemotuzumab Plus Chemotherapy and Anlotinib Induction Followed by Bemotuzumab, Anlotinib and Consolidative Thoracic Radiotherapy in Extensive-Stage Small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial evaluating bemotuzumab with chemotherapy and anlotinib induction followed by consolidative thoracic radiotherapy for …
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: Iparomlimab and Tuvonralimab Injection Combined With Chemotherapy and Sequential Thoracic Radiotherapy for Extensive-Stage Small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial evaluating the combination of iparomlimab and tuvonralimab with chemotherapy and sequential thoracic radiotherapy for…