Ewing Sarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Diffusion Weighted Magnetic Resonance in Imaging Younger Patients With Newly Diagnosed Bone or Soft Tissue Sarcomas [NA]
A completed clinical trial update examining diffusion-weighted MRI imaging in younger patients with newly diagnosed bone or soft-tissue sarc…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Study of Lurbinectedin Monotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Ewing Sarcoma [Phase 1, Phase 2]
A pediatric and young adult phase 1/2 trial is studying lurbinectedin as monotherapy for relapsed/refractory Ewing sarcoma; recruitment is o…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Adherence to a Personalized Home Exercise Program in Patients With Bone Tumor Undergoing Lower Extremity Salvage Surgery
This clinical trial update notes a study evaluating adherence to a personalized home exercise program for bone tumor patients undergoing low…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Selective Antigen Specific T Cells and CAR T Cells in Subjects With Relapsed/Refractory Embryonal Tumors (SABRE) [Phase 1]
Phase 1 SABRE trial evaluating selective antigen-specific T cells and CAR T cells in relapsed/refractory embryonal tumors, including rhabdom…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Biologically-Adapted, Dose-Escalated Radiotherapy for the Treatment of Ewing Sarcoma, BEAR Trial [NA]
The BEAR trial is a Mayo Clinic-sponsored study of biologically adapted, dose-escalated radiotherapy for Ewing sarcoma and related round cel…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: HER2 Chimeric Antigen Receptor (CAR) T Cells in Combination With Checkpoint Blockade in Patients With Advanced Sarcoma [Phase 1]
Phase 1 clinical trial evaluating HER2-targeted CAR T cells in combination with checkpoint blockade for advanced sarcoma; recruitment is ong…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Liquid Biopsy in Ewing Sarcoma and Osteosarcoma as a Prognostic And Response Diagnostic: LEOPARD [NA]
The LEOPARD trial is evaluating liquid biopsy as a prognostic and response diagnostic tool for Ewing sarcoma (bone and soft tissue), Periphe…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Phase Ib / Regorafenib With Conventional Chemotherapy/Newly Diagnosed Patients/ Multimetastatic Ewing Sarcoma [Phase 1]
This entry describes a Phase 1 trial of regorafenib with conventional chemotherapy for newly diagnosed multimetastatic Ewing sarcoma. The st…
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CLINICAL_TRIALS research · 2026-01-02Clinical Trial Update: Observational Study on Skeletal Ewing's Sarcoma
An observational study on skeletal Ewing sarcoma is currently recruiting. Sponsored by the Italian Sarcoma Group.
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults [Phase 1]
Phase 1 clinical trial update describing B7H3-targeted CAR T-cell therapy for recurrent/refractory pediatric solid tumors, including several…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults [Phase 1]
A Phase 1 trial update for EGFR806 CAR T cell immunotherapy in pediatric and young adult patients with recurrent/refractory solid tumors; th…
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CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: Cabozantinib With Ifosfamide in Relapsed/Refractory Sarcomas [Phase 1]
A Phase 1 trial evaluating the combination of cabozantinib with ifosfamide in relapsed/refractory sarcomas is currently recruiting at Childr…
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CLINICAL_TRIALS research · 2025-10-16Clinical Trial Update: Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors [Phase 1]
Phase 1 pediatric trial evaluating alpha/beta CD19+ depleted haploidentical transplantation in combination with Zoledronic acid (Zometa) for…
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CLINICAL_TRIALS research · 2025-10-10Clinical Trial Update: Machine Learning Applied to EHRs Data of Patients With Sarcoma
Completed study from the University of Milano Bicocca applying machine learning to electronic health records of patients with sarcoma (inclu…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Flavored, Oral Irinotecan VAL-413 (Orotecan®) Given With Temozolomide for Treatment of Recurrent Pediatric Solid Tumors [Phase 1]
Phase 1 study evaluating flavored oral irinotecan VAL-413 (Orotecan) with temozolomide for recurrent pediatric solid tumors is currently rec…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: A Phase II Study Evaluating Efficacy and Safety of Regorafenib in Patients With Metastatic Bone Sarcomas [Phase 2]
Phase II clinical trial evaluating regorafenib for metastatic bone sarcomas is active but not recruiting, including Ewing sarcoma, chondrosa…
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: A Post-treatment Program to Identify and Manage Complications Related to Oncology or Hematology Treatments in Cancer Survivors. [NA]
This clinical trial update describes a post-treatment program to identify and manage complications related to oncology or hematology treatme…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Fertility Preservation in Children With Solid Tumors: Detection of Residual Disease by a Sensitive Method
This clinical trial investigates fertility preservation in children with solid tumors and evaluates detection of residual disease using a hi…
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: A Randomized Controlled Study Comparing the Safety and Efficacy of Irinotecan Hydrochloride Liposome Injection Combined With Temozolomide and Vincristine (NALIRI-VT) Versus Irinotecan Combined With Temozolomide and Vincristine (VIT) in Patients With Advanced Ewing's Sarcoma [Phase 2]
A Phase 2 randomized trial comparing liposomal irinotecan-based combination therapy (NALIRI-VT) with standard irinotecan-based therapy (VIT)…
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: C7R-GD2.CART Cells for Patients With Relapsed or Refractory Neuroblastoma and Other GD2 Positive Cancers (GAIL-N) [Phase 1]
ClinicalTrials.gov entry updates the Phase 1 study of C7R-GD2.CART cells for relapsed or refractory GD2-positive cancers, including neurobla…
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: The Risk of Acute Myeloid Leukaemia in Patients With Ewing's Sarcoma
This clinical trial update discusses the risk of developing acute myeloid leukemia in patients diagnosed with Ewing Sarcoma. The study statu…
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CLINICAL_TRIALS research · 2025-07-15Clinical Trial Update: Sequential Infusion of CD146-Targeted and HER2-Targeted CAR T Cells in Patients With Advanced Sarcomas [Phase 1, Phase 2]
A clinical trial update describing a Phase 1/2 study of sequential infusion of CD146-targeted and HER2-targeted CAR T cells in patients with…
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CLINICAL_TRIALS research · 2025-05-31Clinical Trial Update: Phase II Study of Irinotecan Liposome (II) Combined With Temozolomide and Fluzoparib in Recurrent or Metastatic Ewing Sarcoma [Phase 2]
Phase II trial evaluating a triplet regimen of liposomal irinotecan, temozolomide, and fluzoparib for recurrent or metastatic Ewing sarcoma;…
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CLINICAL_TRIALS research · 2025-05-13Clinical Trial Update: Early Ageing During Therapy in AYA Cancer Patients
A clinical trial investigating early ageing during therapy in adolescents and young adults with cancer is currently recruiting. The study co…
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CLINICAL_TRIALS research · 2025-05-11Clinical Trial Update: DFMO Maintenance for Patients With Relapsed/Refractory Ewing Sarcoma or Osteosarcoma [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial evaluating maintenance therapy with DFMO for relapsed or refractory Ewing sarcoma and osteosarcoma is curre…