Esophageal Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-05-22Clinical Trial Update: A Randomized Controlled Trial Evaluating of Prophylactic Irradiation in CRT for cT1bN0M0 ESCC [Phase 3]
A Phase 3 randomized trial in Japan is assessing prophylactic irradiation added to chemoradiotherapy for patients with cT1bN0M0 esophageal s…
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CLINICAL_TRIALS research · 2025-05-22Clinical Trial Update: Diagnostic Accuracy of Endocytoscopy for Superficial Esophageal Neoplasia
A clinical trial update shows an ongoing study evaluating the diagnostic accuracy of endocytoscopy for superficial esophageal neoplasia, enr…
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CLINICAL_TRIALS trial_result · 2025-05-20Clinical Trial Update: A Study of JAB-3312 in Adult Patients With Advanced Solid Tumors in China [Phase 1]
The Phase 1 study of JAB-3312 in adults with advanced solid tumors in China has completed.
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: SLND Versus Non-Dissection Following ESD for T1a Stage Esophageal Squamous Cell Carcinoma [NA]
Clinical trial comparing sentinel lymph node dissection versus no dissection after endoscopic submucosal dissection for T1a stage esophageal…
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CLINICAL_TRIALS trial_result · 2025-05-15Clinical Trial Update: Active Surveillance After Neoadjuvant Adebrelimab Combined With Chemoradiotherapy for Resectable ESCC [Phase 2]
This Phase 2 trial investigates neoadjuvant adebrelimab combined with chemoradiotherapy for resectable esophageal squamous cell carcinoma; t…
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: Carrelizumab, Chemotherapy and Apatinib in the Neoadjuvant Treatment of Resectable Esophageal Squamous Cell Carcinoma [Phase 2]
Phase 2 trial update evaluating carrelizumab in combination with chemotherapy and apatinib as neoadjuvant treatment for resectable esophagea…
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CLINICAL_TRIALS other · 2025-05-14Clinical Trial Update: RAPA-201 Therapy of Solid Tumors [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating RAPA-201 for solid tumors, including small cell and non-small cell lung cancer and several head and neck…
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CLINICAL_TRIALS research · 2025-05-09Clinical Trial Update: Sequential Tegafur-gimeracil-oteracil Potassium Capsule (s-1) and Serplulimab Following Concurrent Chemoradiotherapy for Esophageal Squamous Cell Carcinoma [Phase 2]
Phase 2 trial assessing sequential S-1 chemotherapy followed by Serplulimab after concurrent chemoradiotherapy in locally advanced, inoperab…
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Volatile Organic Compounds as Breath Biomarkers in Squamous Oesophageal Neoplasms
Imperial College London is conducting a study to evaluate volatile organic compounds in breath as biomarkers for esophageal cancers. The tri…
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CLINICAL_TRIALS research · 2025-04-18Clinical Trial Update: Neoadjuvant QL1706 Therapy for ESCC [Phase 2]
A Phase 2 neoadjuvant trial evaluating QL1706 for locally advanced resectable esophageal squamous cell carcinoma is currently recruiting.
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CLINICAL_TRIALS research · 2025-04-17Clinical Trial Update: Benmelstobart Combined With Radiochemotherapy as Neoadjuvant Treatment Iin ESCC [Phase 2]
A Phase 2 clinical trial is evaluating Benmelstobart in combination with radiochemotherapy as neoadjuvant treatment for Esophageal squamous …
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CLINICAL_TRIALS research · 2025-04-16Clinical Trial Update: A Phase II Study of Toripalimab Combined With Sequential Neoadjuvant Chemoradiotherapy in Patients With Esophageal Squamous Cell Carcinoma [Phase 2]
A Phase II clinical trial is evaluating Toripalimab with sequential neoadjuvant chemoradiotherapy for locally advanced esophageal squamous c…
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CLINICAL_TRIALS trial_result · 2025-04-04Clinical Trial Update: Study of XB002 in Subjects With Solid Tumors (JEWEL-101) [Phase 1]
JEWEL-101 is a Phase 1 trial of XB002 in patients with solid tumors, covering multiple indications. The study has completed.
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CLINICAL_TRIALS research · 2025-04-02Clinical Trial Update: Optimizing Neoadjuvant Treatment Regimens for Locally Advanced Esophageal Squamous Cell Carcinoma [Phase 2, Phase 3]
Ongoing Phase 2/Phase 3 trial recruiting to optimize neoadjuvant regimens for locally advanced esophageal squamous cell carcinoma at Peking …
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CLINICAL_TRIALS research · 2025-04-01Clinical Trial Update: Toripalimab Adjuvant Therapy in Subjects With Resected Esophageal Squamous Cell Carcinoma Who Achieved Pathological Complete Response (pCR) [Phase 2]
Phase 2 clinical trial evaluating adjuvant toripalimab after surgical resection for esophageal squamous cell carcinoma in patients achieving…
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CLINICAL_TRIALS research · 2025-03-30Clinical Trial Update: Novel Strategy for Early Detection of Esophageal Squamous Cell Carcinoma [NA]
This clinical trial update reports that a study at University of California, San Francisco is actively recruiting to evaluate a novel strate…
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CLINICAL_TRIALS research · 2025-03-26Clinical Trial Update: A Study to Investigate the Safety, Pharmacokinetics, and Clinical Activity of AP203 in Patients with Locally Advanced or Metastatic Solid Tumors, and Expansion to Selected Malignancies [Phase 1, Phase 2]
An ongoing Phase 1/2 clinical trial evaluating AP203 in patients with locally advanced or metastatic solid tumors, including non-small cell …
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CLINICAL_TRIALS research · 2025-03-25Clinical Trial Update: Efficacy and Safety of Cadonilimab and Chemoradiotherapy in Unresectable Locally Advanced Esophageal Squamous Cell Carcinoma [NA]
This clinical trial update describes a study of cadonilimab in combination with chemoradiotherapy for unresectable locally advanced esophage…
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CLINICAL_TRIALS research · 2025-03-21Clinical Trial Update: Prospective Phase II Clinical Study of Neoadjuvant Chemoradiotherapy Combined With PD-1/PD-L1 Inhibitors in the Treatment of Locally Advanced Resectable Esophageal Squamous Cell Carcinoma [Phase 2]
This document describes a prospective Phase II study evaluating neoadjuvant chemoradiotherapy combined with PD-1/PD-L1 inhibitors for locall…
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: A Multicenter Cancer Biospecimen Collection Study
A multicenter cancer biospecimen collection trial sponsored by Cofactor Genomics is currently recruiting, covering multiple cancer indicatio…
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CLINICAL_TRIALS research · 2025-03-11Clinical Trial Update: Total Neoadjuvant Therapy Combined With Adebrelimab in Locally Advanced Resectable ESCC [Phase 2, Phase 3]
A clinical trial update evaluating total neoadjuvant therapy combined with the PD-1 inhibitor adebrelimab for locally advanced resectable es…
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CLINICAL_TRIALS trial_result · 2025-03-10Clinical Trial Update: A Study of Ladiratuzumab Vedotin in Advanced Solid Tumors [Phase 2]
Phase 2 trial of ladiratuzumab vedotin in multiple advanced solid tumors was terminated, with results posted in March 2025.
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CLINICAL_TRIALS research · 2025-03-07Clinical Trial Update: A Multicenter Trial of YSQTG vs. Simulated Agents With Neoadjuvant Chemoradiotherapy or Chemoimmunotherapy for EC [NA]
A multicenter trial is evaluating YSQTG versus simulated agents with neoadjuvant chemoradiotherapy or chemoimmunotherapy for esophageal squa…
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CLINICAL_TRIALS research · 2025-03-06Clinical Trial Update: Chemoradiotherapy Followed by Planned Surgery or by Surveillance and Surgery Only When Needed for Oesophageal Cancer [Phase 3]
A Phase 3 trial comparing chemoradiotherapy followed by planned surgery versus surveillance with surgery only if needed for esophageal squam…
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CLINICAL_TRIALS trial_result · 2025-02-28Clinical Trial Update: Tislelizumab as Single-Agent Neoadjuvant Immunotherapy in Resectable Esophageal Squamous Cell Carcinoma [Phase 2]
A Phase 2 clinical trial evaluating tislelizumab as a single-agent neoadjuvant immunotherapy for resectable esophageal squamous cell carcino…