Esophageal Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-09-18Clinical Trial Update: Predicting Pathological Complete Response in Esophageal Squamous Cell Carcinoma Using a Multimodal Model Integrating Clinical, Radiomics, and Deep Learning Features
A completed clinical trial evaluated a multimodal model that integrates clinical data, radiomics, and deep learning features to predict path…
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: Biomarker Based Neoadjuvant Strategies for Locally Advanced Resectable ESCC [Phase 2]
Phase 2 clinical trial update on biomarker-based neoadjuvant strategies for locally advanced resectable esophageal squamous cell carcinoma, …
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: Low-Dose Radiotherapy in Patients With Advanced Esophageal Squamous Cell Carcinoma Resistant to First-Line Chemotherapy Combined With Immunotherapy [Phase 2]
Phase 2 trial not yet recruiting evaluating low-dose radiotherapy in patients with advanced esophageal squamous cell carcinoma resistant to …
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: Chemoradiation and Pembrolizumab Followed by Pembrolizumab and Lenvatinib Before Surgery for the Treatment of Non-metastatic Esophageal or Esophageal/Gastroesophageal Junction Cancer [Phase 2]
A Phase 2 clinical trial update evaluating chemoradiation with pembrolizumab, followed by pembrolizumab and lenvatinib before surgery for no…
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CLINICAL_TRIALS trial_result · 2025-09-03Clinical Trial Update: Study of SHR-8068 Combined With Adebrelimab and Platinum-containing Chemotherapy in the Treatment of Advanced Gastric and Esophageal Cancer [Phase 2]
A Phase 2 clinical trial update evaluating SHR-8068 in combination with Adebrelimab and platinum-based chemotherapy for advanced gastric ade…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Brachytherapy With Radiotherapy and Immunotherapy: Guided HDR Trial in Esophageal Squamous Cell Carcinoma [Phase 2]
Phase 2 clinical trial evaluating brachytherapy with radiotherapy and immunotherapy for esophageal squamous cell carcinoma, sponsored by Nat…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Multi-omics Monitoring of Dynamic Evolution in Esophageal Squamous Cell Carcinoma: PKU-ESCC-Monitor
A ClinicalTrials.gov entry from Peking University Cancer Hospital & Institute describes an upcoming study using multi-omics monitoring to st…
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CLINICAL_TRIALS research · 2025-08-29Clinical Trial Update: Predictive Biomarkers for PD-1 Inhibitor Response in Squamous Cell Carcinoma
This clinical trial update discusses predictive biomarkers for response to PD-1 inhibitors in squamous cell carcinomas, spanning esophageal,…
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CLINICAL_TRIALS research · 2025-08-29Clinical Trial Update: Neoadjuvant ChemoRadiotherapy Followed by Immunotherapy and Surgery for Resectable Esophageal Squamous Cell Carcinoma(CRIS-2 Trial) [Phase 2]
A Phase 2 trial (CRIS-2) is evaluating neoadjuvant chemoradiotherapy followed by immunotherapy and surgery for resectable esophageal squamou…
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CLINICAL_TRIALS trial_result · 2025-08-26Clinical Trial Update: A Study of Trifluridine/Tipiracil Combined With Anlotinib as Second-line Treatment for Recurrent and Metastatic Esophageal Squamous Cell Carcinoma [Phase 2]
Phase 2 clinical trial evaluating the combination of Trifluridine/Tipiracil with Anlotinib as second-line treatment for recurrent and metast…
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CLINICAL_TRIALS withdrawal · 2025-08-26Clinical Trial Update: Adebrelimab Combined With Chemoradiotherapy for Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma (ESCC) [NA]
A clinical trial evaluating adebrelimab in combination with chemoradiotherapy for locally advanced unresectable esophageal squamous cell car…
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CLINICAL_TRIALS trial_result · 2025-08-24Clinical Trial Update: PPIO-004 Clinical Application of Efficacy Prediction Model Based on Epigenomics Sequencing Technology in Neoadjuvant Immunotherapy for Esophageal Cancer [Phase 2]
This update reports the completion of a Phase 2 trial evaluating the PPIO-004 efficacy-prediction model using epigenomics sequencing in neoa…
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CLINICAL_TRIALS trial_result · 2025-08-20Clinical Trial Update: A Dose Escalation and Expansion Study of Lomvastomig, a PD-1/TIM-3 Bispecific Antibody, in Participants With Advanced and/or Metastatic Solid Tumors [Phase 1]
This Phase 1 trial assesses safety, tolerability, and preliminary efficacy of lomvastomig, a PD-1/TIM-3 bispecific antibody, in adults with …
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: A Single-center, Multicohort, Phase II Clinical Study Evaluating the Combination Therapy of Sacituzumab Tirumotecan in Patients With Unresectable, Locally Advanced, Recurrent, or Metastatic Esophageal Squamous Cell Carcinoma [Phase 2]
A Phase II clinical trial is evaluating the combination of Sacituzumab Tirumotecan in patients with unresectable, locally advanced, recurren…
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: Lymphocyte-sparing Thoracic Radiotherapy for Esophageal Squamous Cell Carcinoma [NA]
This clinical trial update notes a study on lymphocyte-sparing thoracic radiotherapy for esophageal squamous cell carcinoma, sponsored by Ru…
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: A Phase II Clinical Study of Induction Adebrelimab Combined With Chemotherapy Followed by Concurrent Chemoradiotherapy for Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma (ESCC) [Phase 2]
Phase II clinical trial evaluating induction adebrelimab with chemotherapy followed by concurrent chemoradiotherapy for locally advanced unr…
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: A Clinical Study on the Efficacy and Safety of Paclitaxel Polymeric Micelles and Cisplatin Combined With Cadonilimab as a Neoadjuvant Therapy for Locally Advanced Esophageal Squamous Cell Carcinoma [Phase 2]
Phase 2 clinical trial evaluating paclitaxel polymeric micelles and cisplatin with cadonilimab as neoadjuvant therapy for locally advanced e…
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CLINICAL_TRIALS trial_result · 2025-08-06Clinical Trial Update: A Study of Apatinib Plus Radiotherapy and S-1 for Treatment of Refractory or Metastatic Esophageal Squamous Cell Carcinoma [Phase 2]
Phase 2 trial evaluating apatinib plus radiotherapy and S-1 for refractory or metastatic esophageal squamous cell carcinoma was terminated.
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CLINICAL_TRIALS trial_result · 2025-08-03Clinical Trial Update: A Study of DKN-01 in Combination With Paclitaxel or Pembrolizumab [Phase 1]
Phase 1 study of DKN-01 with paclitaxel or pembrolizumab in esophageal and gastroesophageal cancers has been completed.
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: Deep Learning Model Predicts Pathological Complete Response of Esophageal Squamous Cell Carcinoma Following Neoadjuvant Immunochemotherapy
A clinical trial update describes a deep learning model that predicts pathological complete response in esophageal squamous cell carcinoma a…
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CLINICAL_TRIALS trial_result · 2025-07-23Clinical Trial Update: Endostar Combined With IP Second-line Treatment of Advanced Esophageal Squamous Cell Carcinomas [Phase 2]
A Phase 2 clinical trial evaluating Endostar in combination with the IP chemotherapy regimen (irinotecan + cisplatin) for second-line treatm…
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: An Observational Study on the Safety and Efficacy of Immunotherapy Combined With Concurrent Chemoradiotherapy in Elderly Patients With Esophageal Squamous Cell Carcinoma
An observational study evaluating the safety and efficacy of immunotherapy combined with concurrent chemoradiotherapy in elderly patients wi…
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CLINICAL_TRIALS research · 2025-07-21Clinical Trial Update: Fraction Dose Escalation of Split-course Hypofractionated Concurrent Chemoradiotherapy Following Induction Chemo-immunotherapy in Unresectable Locally Advanced Esophageal Squamous Carcinoma: a Phase I Study. [Phase 1]
Phase I trial evaluating dose escalation of split-course hypofractionated concurrent chemoradiotherapy after induction chemo-immunotherapy i…
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CLINICAL_TRIALS research · 2025-07-20Clinical Trial Update: Tislelizumab Combined With Chemotherapy for Resectable Esophageal Squamous Cell Carcinoma Followed by CRT or Surgery [Phase 2]
Phase 2 clinical trial update for tislelizumab plus chemotherapy in resectable esophageal squamous cell carcinoma, followed by chemoradiothe…
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CLINICAL_TRIALS research · 2025-07-20Clinical Trial Update: CT and Endoscopic Biopsy Image-Based Deep Learning for Predicting Left Recurrent Laryngeal Nerve Lymph Node Metastasis in Esophageal Cancer
The document reports a clinical trial using CT and endoscopic biopsy image-based deep learning to predict left recurrent laryngeal nerve lym…