Esophageal Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Adebrelimab ±Induction Chemotherapy Followed by Concurrent Chemoradiotherapy for Unresectable Locally Advanced ESCC [Phase 2]
Phase 2 clinical trial evaluating adebrelimab with or without induction chemotherapy followed by concurrent chemoradiotherapy for unresectab…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Study of Adebrelimab With Chemotherapy, Endoscopy and Sequential Chemoradiotherapy In Inoperable Esophageal Cancer [Phase 2]
Phase 2 clinical trial evaluating Adebrelimab with chemotherapy, endoscopy, and sequential chemoradiotherapy in esophageal squamous cell car…
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CLINICAL_TRIALS other · 2024-09-19Clinical Trial Update: BTLA Inhibitor (JS004) Combined with Toripalimab and Chemotherapy in the Perioperative Treatment of Resectable Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma [Phase 2]
Phase 2 trial update on combining BTLA inhibitor JS004 with toripalimab and chemotherapy as perioperative treatment for resectable locally a…
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CLINICAL_TRIALS other · 2024-09-19Clinical Trial Update: Neoadjuvant Chemoimmunotherapy Followed by Surgery and Postoperative Radioimmunotherapy [NA]
A clinical trial entry describing neoadjuvant chemoimmunotherapy followed by surgery and postoperative radioimmunotherapy for esophageal squ…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: A Phase II Exploratory Clinical Trial of Multiple Drug Combinations in the Treatment of Advanced Esophageal Squamous Cell Carcinoma [Phase 2]
Phase II exploratory clinical trial evaluating multiple drug combinations for advanced esophageal squamous cell carcinoma; currently recruit…
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CLINICAL_TRIALS research · 2024-08-29Clinical Trial Update: Individualized Tumor-Informed CtDNA Analysis for Monitoring Postoperative Recurrence in ESCC (NEOCRTEC2401)
Trial evaluating individualized tumor-informed circulating tumor DNA analysis to monitor postoperative recurrence in patients with esophagea…
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CLINICAL_TRIALS trial_result · 2024-08-27Clinical Trial Update: High-concentration Small-volume Versus Low-concentration Large-volume Iodine Solution for Esophageal Chromoendoscopy [NA]
This completed clinical trial compares high-concentration small-volume iodine solution with low-concentration large-volume iodine solution f…
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CLINICAL_TRIALS research · 2024-08-21Clinical Trial Update: Sintilimab With Chemotherapy Plus PEG-rhG-GSF for Neoadjuvant Treatment of Esophageal Squamous Cell Carcinoma [Phase 3]
A Phase 3 trial is evaluating Sintilimab combined with chemotherapy and PEG-rhG-GSF as neoadjuvant therapy for Esophageal Squamous Cell Carc…
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CLINICAL_TRIALS trial_result · 2024-08-16Clinical Trial Update: Anastomotic Leaks in Esophageal Squamous Cell Carcinoma Patients After Trimodal Therapy
The clinical trial evaluating anastomotic leaks in patients with esophageal squamous cell carcinoma after trimodal therapy has completed.
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CLINICAL_TRIALS trial_result · 2024-08-06Clinical Trial Update: Study of ASP0739 Alone and With Pembrolizumab in Advanced Solid Tumors With NY-ESO-1 Expression Participants [Phase 1, Phase 2]
Phase 1/2 study evaluating ASP0739 alone and in combination with pembrolizumab in NY-ESO-1 expressing advanced solid tumors was terminated, …
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CLINICAL_TRIALS research · 2024-07-31Clinical Trial Update: Surufatinib Combined With Serplulimab and Standard Chemotherapy as First-line Treatment in Advanced Solid Tumors With Neuroendocrine Differentiation [Phase 2]
Phase 2 study evaluating first-line surufatinib plus serplulimab with standard chemotherapy for advanced solid tumors with neuroendocrine di…
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CLINICAL_TRIALS research · 2024-07-26Clinical Trial Update: TGF-β And PDL-1 Inhibition in Esophageal Squamous Cell Carcinoma Combined With Chemoradiation TheRapY [NA]
A clinical trial evaluating the combination of TGF-β inhibition and PD-L1 inhibition with chemoradiation for esophageal squamous cell carcin…
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CLINICAL_TRIALS research · 2024-07-24Clinical Trial Update: Sintilimab and Chemotherapy Sequential Radiotherapy in Advanced Esophageal Cancer [Phase 2, Phase 3]
Clinical trial update for Sintilimab with chemotherapy followed by sequential radiotherapy in metastatic Esophageal Squamous Cell Carcinoma;…
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CLINICAL_TRIALS research · 2024-07-22Clinical Trial Update: A Study of Simmitinib Plus Irinotecan in Advanced Esophageal Squamous Cell Carcinoma [Phase 2]
A Phase 2 clinical trial evaluating simmitinib in combination with irinotecan for advanced esophageal squamous cell carcinoma is currently r…
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CLINICAL_TRIALS trial_result · 2024-07-18Clinical Trial Update: M6620 Plus Standard Treatment in Oesophageal and Other Cancer [Phase 1]
Phase 1 trial evaluating M6620 in combination with standard treatment for esophageal cancer (esophageal adenocarcinoma and esophageal squamo…
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CLINICAL_TRIALS research · 2024-07-18Clinical Trial Update: Adebrelimab Combined With Albumin Paclitaxel and Nedaplatin as Neoadjuvant Therapy for Locally Advanced Resectable ESCC [Phase 2]
Phase 2 trial evaluating adebrelimab combined with nab-paclitaxel (albumin-bound paclitaxel) and nedaplatin as neoadjuvant therapy for local…
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CLINICAL_TRIALS research · 2024-07-17Clinical Trial Update: PPIO-008 Tislelizumab Combined With S-1 in Patients With ypT+N0 ESCC After Radical Resection With Neoadjuvant STUDY [Phase 2]
A Phase 2 clinical trial (NCT06354140) evaluating PPIO-008 with tislelizumab and S-1 for patients with ypT+N0 esophageal squamous cell carci…
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CLINICAL_TRIALS trial_result · 2024-07-16Clinical Trial Update: Sintilimab After Concurrent Chemoradiotherapy in Elderly Patients With Esophageal Squamous Cell Carcinoma [Phase 2]
Phase 2 clinical trial evaluating sintilimab after concurrent chemoradiotherapy in elderly patients with esophageal squamous cell carcinoma;…
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CLINICAL_TRIALS research · 2024-07-16Clinical Trial Update: Adjuvant Radiotherapy for Esophageal Squamous Cell Carcinoma in the Era of Immunotherapy [Phase 2]
A Phase 2 clinical trial assessing adjuvant radiotherapy for esophageal squamous cell carcinoma in the era of immunotherapy; recruitment is …
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CLINICAL_TRIALS research · 2024-07-15Clinical Trial Update: Liposomal Irinotecan and 5-FU as Second-line Therapy for Patients With ESCC [Phase 3]
This is a Phase 3 study evaluating liposomal irinotecan with 5-fluorouracil as second-line therapy for esophageal squamous cell carcinoma; t…
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CLINICAL_TRIALS trial_result · 2024-07-08Clinical Trial Update: BI-754091 and Afatinib for Refractory Esophageal Squamous Cell Carcinoma (BEAR Study) [Phase 2]
A Phase 2 BEAR study investigating BI-754091 in combination with Afatinib for refractory esophageal squamous cell carcinoma has completed.
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CLINICAL_TRIALS research · 2024-07-08Clinical Trial Update: Liposomal Irinotecan With Cisplatin and Concurrent Radiotherapy in Locally Advanced Esophageal Squamous Cell Carcinoma [Phase 1]
A Phase 1 clinical trial evaluating liposomal irinotecan with cisplatin and concurrent radiotherapy for locally advanced Esophageal squamous…
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CLINICAL_TRIALS research · 2024-07-05Clinical Trial Update: A Phase lb/lI Clinical Study in Advanced or Metastatic Esophageal Squamous Cell Carcinoma [Phase 2]
Update on a Phase 1b/2 clinical study for advanced or metastatic esophageal squamous cell carcinoma; the trial is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: Pre-Operative Pembrolizumab + Chemoradiation in Patients With Locally Advanced Esophageal Squamous Cell Carcinoma [Phase 2]
Phase 2 trial evaluating pre-operative pembrolizumab plus chemoradiation in locally advanced esophageal squamous cell carcinoma has complete…
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CLINICAL_TRIALS other · 2024-07-01Clinical Trial Update: Neoadjuvant PD-1 Blockade for Elderly Esophageal Squamous Cell Carcinoma (BLESS) [Phase 2]
A Phase 2 trial (BLESS) is investigating neoadjuvant PD-1 blockade in elderly patients with esophageal squamous cell carcinoma. The study is…