Esophageal Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-10-16Clinical Trial Update: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors [Phase 1]
Phase 1 clinical trial of INCB099318 in participants with advanced solid tumors has been terminated. The update reports safety, tolerability…
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: A Study of IPM514 in Patients With Esophageal Squamous Cell Carcinoma. [Phase 1]
This is a Phase 1 trial update for IPM514 in patients with esophageal squamous cell carcinoma, with the study currently not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: PPIO-005 The Relationship Between Different Nutritional Pathways and Tumor Outcomes After Minimally Invasive Esophagectomy
This completed clinical trial from Daping Hospital investigates how different nutritional pathways influence tumor outcomes after minimally …
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: Phase Ib Study of TNO155 in Combination With Spartalizumab or Ribociclib in Selected Malignancies [Phase 1]
Phase Ib study of TNO155 in combination with Spartalizumab or Ribociclib in selected malignancies was terminated, involving multiple indicat…
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: PPIO-007 Correlation Analysis of Type II Diabetes Mellitus on Short-term and Long-term Outcomes of Patients With Esophageal Squamous Cell Cancer Undergoing Minimally Invasive Esophagectomy
Completed study evaluating the correlation between Type II Diabetes Mellitus and short- and long-term outcomes after minimally invasive esop…
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CLINICAL_TRIALS trial_result · 2025-09-18Clinical Trial Update: Predicting Pathological Complete Response in Esophageal Squamous Cell Carcinoma Using a Multimodal Model Integrating Clinical, Radiomics, and Deep Learning Features
A completed clinical trial evaluated a multimodal model that integrates clinical data, radiomics, and deep learning features to predict path…
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CLINICAL_TRIALS trial_result · 2025-09-03Clinical Trial Update: Study of SHR-8068 Combined With Adebrelimab and Platinum-containing Chemotherapy in the Treatment of Advanced Gastric and Esophageal Cancer [Phase 2]
A Phase 2 clinical trial update evaluating SHR-8068 in combination with Adebrelimab and platinum-based chemotherapy for advanced gastric ade…
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CLINICAL_TRIALS trial_result · 2025-08-26Clinical Trial Update: A Study of Trifluridine/Tipiracil Combined With Anlotinib as Second-line Treatment for Recurrent and Metastatic Esophageal Squamous Cell Carcinoma [Phase 2]
Phase 2 clinical trial evaluating the combination of Trifluridine/Tipiracil with Anlotinib as second-line treatment for recurrent and metast…
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CLINICAL_TRIALS trial_result · 2025-08-24Clinical Trial Update: PPIO-004 Clinical Application of Efficacy Prediction Model Based on Epigenomics Sequencing Technology in Neoadjuvant Immunotherapy for Esophageal Cancer [Phase 2]
This update reports the completion of a Phase 2 trial evaluating the PPIO-004 efficacy-prediction model using epigenomics sequencing in neoa…
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CLINICAL_TRIALS trial_result · 2025-08-20Clinical Trial Update: A Dose Escalation and Expansion Study of Lomvastomig, a PD-1/TIM-3 Bispecific Antibody, in Participants With Advanced and/or Metastatic Solid Tumors [Phase 1]
This Phase 1 trial assesses safety, tolerability, and preliminary efficacy of lomvastomig, a PD-1/TIM-3 bispecific antibody, in adults with …
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CLINICAL_TRIALS trial_result · 2025-08-06Clinical Trial Update: A Study of Apatinib Plus Radiotherapy and S-1 for Treatment of Refractory or Metastatic Esophageal Squamous Cell Carcinoma [Phase 2]
Phase 2 trial evaluating apatinib plus radiotherapy and S-1 for refractory or metastatic esophageal squamous cell carcinoma was terminated.
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CLINICAL_TRIALS trial_result · 2025-08-03Clinical Trial Update: A Study of DKN-01 in Combination With Paclitaxel or Pembrolizumab [Phase 1]
Phase 1 study of DKN-01 with paclitaxel or pembrolizumab in esophageal and gastroesophageal cancers has been completed.
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CLINICAL_TRIALS trial_result · 2025-07-23Clinical Trial Update: Endostar Combined With IP Second-line Treatment of Advanced Esophageal Squamous Cell Carcinomas [Phase 2]
A Phase 2 clinical trial evaluating Endostar in combination with the IP chemotherapy regimen (irinotecan + cisplatin) for second-line treatm…
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CLINICAL_TRIALS trial_result · 2025-07-16Clinical Trial Update: Clinical Trial to Evaluate the Safety and Effectiveness of TQB2618 Injection Combined Therapy in Patients With Advanced Esophageal Squamous Cell Carcinoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the safety and effectiveness of TQB2618 Injection Combined Therapy in advanced esophageal squamous cel…
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CLINICAL_TRIALS trial_result · 2025-07-14Clinical Trial Update: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099280 in Participants With Advanced Solid Tumors [Phase 1]
This Phase 1 trial reports on the safety, tolerability, pharmacokinetics, and pharmacodynamics of INCB099280 in participants with advanced s…
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: QL1706 Plus Celecoxib in Advanced Esophageal Squamous Cell Carcinoma [Phase 2]
A Phase 2 trial is evaluating QL1706 in combination with Celecoxib for advanced esophageal squamous cell carcinoma; the study status is not …
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CLINICAL_TRIALS trial_result · 2025-07-01Clinical Trial Update: A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With Gastrointestinal Cancer (Master Protocol) (Pegathor Gastrointestinal 203) [Phase 2]
This is a Phase 2 master protocol evaluating SAR444245 in combination with other anticancer therapies for several gastrointestinal cancers; …
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CLINICAL_TRIALS trial_result · 2025-06-13Clinical Trial Update: Study To Investigate the Efficacy and Safety of Sitravatinib in Combination With Tislelizumab in Participants With Esophageal Squamous Cell Carcinoma [Phase 2]
A Phase 2 trial evaluating sitravatinib plus tislelizumab in Esophageal Squamous Cell Carcinoma has been terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2025-06-13Clinical Trial Update: A Study of LGK974 in Patients With Malignancies Dependent on Wnt Ligands [Phase 1]
Phase 1 clinical trial update of LGK974, a Wnt pathway inhibitor, in malignancies dependent on Wnt ligands; the study included several cance…
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CLINICAL_TRIALS trial_result · 2025-06-13Clinical Trial Update: Tislelizumab Combined With Chemotherapy for the Perioperative Treatment of Esophageal Squamous Carcinoma [Phase 2]
Phase 2 trial evaluating tislelizumab in combination with chemotherapy as perioperative treatment for esophageal squamous cell carcinoma; th…
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CLINICAL_TRIALS trial_result · 2025-06-12Clinical Trial Update: Efficacy and Safety of Preoperative Sintilimab Plus Nab-paclitaxel and Cisplatin in BR-ESCC Patients [Phase 2]
A Phase 2 neoadjuvant trial evaluating the combination of sintilimab with nab-paclitaxel and cisplatin in BR-Esophageal Squamous Cell Carcin…
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CLINICAL_TRIALS trial_result · 2025-06-11Clinical Trial Update: Concurrent Radiotherapy Following Induction Chemoimmunotherapy for Locally Advanced Esophageal Cancer [Phase 2]
A Phase 2 trial evaluating induction chemoimmunotherapy followed by concurrent radiotherapy for locally advanced esophageal squamous cell ca…
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CLINICAL_TRIALS trial_result · 2025-06-08Clinical Trial Update: Testing the Addition of an Anti-cancer Drug, Adavosertib, to Radiation Therapy for Patients With Incurable Esophageal and Gastroesophageal Junction Cancers [Phase 1]
Phase 1 trial updating on the addition of Adavosertib to radiation therapy in patients with incurable esophageal and gastroesophageal juncti…
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CLINICAL_TRIALS trial_result · 2025-05-31Clinical Trial Update: A Feasibility Trial of Nivolumab With Neoadjuvant CF or DCF Therapy for Locally Advanced Esophageal Carcinoma [Phase 1]
Phase 1 feasibility trial evaluating nivolumab added to neoadjuvant CF or DCF chemotherapy in locally advanced esophageal squamous cell carc…
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CLINICAL_TRIALS trial_result · 2025-05-20Clinical Trial Update: A Study of JAB-3312 in Adult Patients With Advanced Solid Tumors in China [Phase 1]
The Phase 1 study of JAB-3312 in adults with advanced solid tumors in China has completed.