Esophageal Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Exploratory Clinical Trial of Oral Paclitaxel Plus Radiotherapy in Patients With Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma [Phase 2]
An exploratory Phase 2 clinical trial evaluating oral paclitaxel plus radiotherapy for locally advanced unresectable esophageal squamous cel…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Induction Immunochemotherapy Followed by Concurrent Chemoradiotherapy in Patients With ESCC. [Phase 2]
An update on a Phase 2 trial evaluating induction immunochemotherapy followed by concurrent chemoradiotherapy in patients with esophageal sq…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Adebrelimab Combined With Chemotherapy for the Esophageal Squamous Cell Carcinoma [NA]
A clinical trial evaluating adebrelimab in combination with chemotherapy for esophageal squamous cell carcinoma is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Phase 1/2 Study Evaluating MCLA-129, a Human Anti-EGFR, Anti-c-MET Bispecific Antibody, in Advanced NSCLC and Other Solid Tumors, Alone and in Combination [Phase 1, Phase 2]
Phase 1/2 trial update evaluating MCLA-129, a bispecific anti-EGFR and anti-c-MET antibody, in advanced non-small cell lung cancer and other…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors [Phase 1]
Phase 1 study update for NRM-823 in locally advanced or metastatic refractory solid tumors, currently recruiting. The trial lists head and n…
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: Short-course Radiotherapy Combined With Serplulimab and Chemotherapy as Neoadjuvant Treatment for Resectable ESCC [Phase 2]
A Phase 2 clinical trial evaluating short-course radiotherapy in combination with serplulimab and chemotherapy as neoadjuvant therapy for re…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Real-world Experience of ICIs Plus Chemotherapy for Advanced ESCC.
A completed real-world study examining immune checkpoint inhibitors combined with chemotherapy for advanced/metastatic esophageal squamous c…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: DCRT vs. Surgery in Resectable ESCC Patient Achiving cCR/PR After nCI [Phase 2]
Phase 2 trial comparing definitive chemoradiation therapy versus surgery in patients with resectable esophageal squamous cell carcinoma who …
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Neoadjuvant Chemoimmunotherapy or Chemoradiotherapy in ESCC [Phase 2]
Phase 2 trial exploring neoadjuvant chemoimmunotherapy or chemoradiotherapy for resectable esophageal squamous cell carcinoma; status is NOT…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Adebrelimab Neoadjuvant Treatment for Resectable ESCC [NA]
The document reports a clinical trial evaluating adebrelimab as neoadjuvant therapy for resectable esophageal squamous cell carcinoma, with …
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: A Prospective, Multicenter, Phase Ib/II Trial of Ivonescimab (AK112) Combined With Albumin-Paclitaxel and Cisplatin as Neoadjuvant Therapy for ESCC [Phase 1, Phase 2]
This is a multicenter Phase Ib/II trial evaluating Ivonescimab (AK112) in combination with albumin-bound paclitaxel and cisplatin as neoadju…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Chemoradiotherapy Following Immunotherapy Plus Chemotherapy for Locally-advanced Esophageal Squamous Cell Cancer (RICE) [Phase 2]
Phase 2 clinical trial evaluating sequential treatment with immunotherapy plus chemotherapy followed by chemoradiotherapy for locally-advanc…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Neoadjuvant Treatment of Toripalimab Combined With Nab-paclitaxel and Platinum Versus Neoadjuvant Docetaxel Combined With Cisplatin and 5-fluorouracil (DCF) in Esophageal Squamous Cell Carcinoma [Phase 3]
A Phase 3 clinical trial compares neoadjuvant toripalimab plus nab-paclitaxel and platinum against neoadjuvant docetaxel with cisplatin and …
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Indocyanine Green-guided Omental Shield Anastomosis for Cervical Esophagogastric Anastomosis in Minimally Invasive McKeown Esophagectomy [Phase 2]
Phase 2 clinical trial evaluating indocyanine green-guided omental shield anastomosis during cervical esophagogastric anastomosis in minimal…
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Study of Durvalumab Versus Placebo in Combination With Definitive Chemoradiation Therapy in Patient With ESCC [Phase 3]
Phase 3 clinical trial comparing durvalumab plus definitive chemoradiation versus placebo with chemoradiation for esophageal squamous cell c…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Registry Platform Gastric/Esophageal Cancer (SAPHIR)
This Clinical Trial Update reports an ongoing registry platform trial SAPHIR addressing gastric and esophageal cancers, currently recruiting…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Neoadjuvant Immunochemotherapy and Chemoradiotherapy Followed by Surgery for Advanced Esophageal Squamous Cell Carcinoma [Phase 2]
Phase 2 clinical trial conducted by National Taiwan University Hospital evaluating neoadjuvant immunochemotherapy and chemoradiotherapy foll…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Based on ctDNA-MRD Guided Adjuvant Treatment Escalation After Definitive Chemoradiotherapy for Unresectable Locally Advanced Esophageal Squamous Cell Carcinoma: a Study on Safety and Efficacy [EARLY_Phase 1]
A Phase 1 trial assessing the safety and potential efficacy of ctDNA MRD-guided escalation of adjuvant therapy after definitive chemoradioth…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: MR-Guided Radiotherapy Dose Escalation Trial for Esophageal Squamous Cell Carcinoma [Phase 1]
Phase 1 trial evaluating MR-guided radiotherapy dose escalation for esophageal squamous cell carcinoma, currently recruiting.
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Radiotherapy Combined With Immunochemotherapy in Metastatic Esophageal Squamous Cell Carcinoma [Phase 2]
This is an update on an ongoing Phase 2 clinical trial evaluating radiotherapy combined with immunochemotherapy for metastatic esophageal sq…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Select Advanced Solid Tumor Indications Receiving Intravenous (IV) ABBV-400 [Phase 1]
Phase 1 study assessing adverse events and change in disease activity in adults with select advanced solid tumors treated with ABBV-400; the…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Standardized Management of Esophageal Fistula in Esophageal Squamous Cell Carcinoma
This clinical trial update describes standardized management strategies for esophageal fistula in patients with esophageal squamous cell car…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Multicenter Prospective Cohort on Esophageal Endoscopic Submucosal Dissection
A multicenter prospective cohort study evaluating esophageal endoscopic submucosal dissection for superficial esophageal cancer and Barrett'…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Intestinal Low-Dose Radiotherapy Plus Immunochemotherapy for Conversion of Borderline Resectable/Unresectable Esophageal Squamous Cell Carcinoma [Phase 2]
A Phase 2 clinical trial evaluating intestinal low-dose radiotherapy plus immunochemotherapy, including tislelizumab, to convert borderline …
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Trial of Nivolumab and Cetuximab After Chemoradiation in Esophageal Squamous Cell Carcinoma Patients. [Phase 2]
This update covers a Phase 2 trial evaluating nivolumab in combination with cetuximab after chemoradiation for esophageal squamous cell carc…