Esophageal Adenocarcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-02-02Clinical Trial Update: A Study of PRT7732, an Oral SMARCA2 Degrader, in Patients With Advanced or Metastatic Solid Tumors With a SMARCA4 Mutation [Phase 1]
A Phase 1 study of PRT7732, an oral SMARCA2 degrader, in patients with SMARCA4-mutant advanced or metastatic solid tumors has been terminate…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Will a Pre-therapy Exercise Intervention Improve the Outcomes of Patients With Advanced Oesophageal Cancer? [NA]
A University of Surrey trial is exploring whether a pre-therapy exercise program can improve outcomes for patients with advanced esophageal …
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: ProofPrincip IntraTu TCells SinglDoseImmunCheckpoinInhib Gastro-Esophage Adenocarcinoma w/ARID1a Mu [EARLY_Phase 1]
Early-phase trial update on ProofPrincip intra-tumoral T cells with a single-dose checkpoint inhibitor for gastroesophageal adenocarcinoma w…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Registry Platform Gastric/Esophageal Cancer (SAPHIR)
This Clinical Trial Update reports an ongoing registry platform trial SAPHIR addressing gastric and esophageal cancers, currently recruiting…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: A Study of KK2269 in Adult Participants With Solid Tumors [Phase 1]
Phase 1 study update for KK2269 in adults with solid tumors; the trial is currently recruiting. Indications include gastric adenocarcinoma, …
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Minimally Invasive Molecular Approaches for the Diagnosis of Barrett's Esophagus and Esophageal Adenocarcinoma [NA]
A Mayo Clinic-sponsored clinical trial is evaluating minimally invasive molecular methods for diagnosing Barrett's esophagus and esophageal …
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Combination of Chemotherapy and Adaptive MR-Guided Radiotherapy to Improve Outcomes in Patients With Esophageal Adenocarcinoma [Phase 1]
A Phase 1 trial assessing the combination of chemotherapy and adaptive MR-guided radiotherapy for esophageal adenocarcinoma and gastroesopha…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Cabozantinib Plus Durvalumab With or Without Tremelimumab in Patients With Gastroesophageal Cancer and Other Gastrointestinal Malignancies [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating cabozantinib plus durvalumab with or without tremelimumab in patients with gastroesophageal cancer and o…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Multicenter Prospective Cohort on Esophageal Endoscopic Submucosal Dissection
A multicenter prospective cohort study evaluating esophageal endoscopic submucosal dissection for superficial esophageal cancer and Barrett'…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Neoadjuvant Intra-tumoral RP2 and FLOT in Gastroesophageal Adenocarcinoma [Phase 2]
A Phase 2 neoadjuvant trial evaluating intra-tumoral RP2 in combination with the FLOT regimen for gastric and esophageal adenocarcinoma is l…
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: Induction FLOT With CROSS CRT for Esophageal Cancer [Phase 2]
A Phase 2 clinical trial evaluating induction FLOT chemotherapy followed by CROSS chemoradiation for esophageal or gastroesophageal junction…
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CLINICAL_TRIALS research · 2026-01-02Clinical Trial Update: Propranolol With Standard Chemoradiation for Esophageal Adenocarcinoma [Phase 2]
A Phase 2 trial is examining propranolol in combination with standard chemoradiation for esophageal adenocarcinoma, currently in recruitment…
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CLINICAL_TRIALS trial_result · 2025-12-30Clinical Trial Update: Impact of Arterial Partial Pressure of Oxygen on Anastomotic Leakage After Esophagectomy
A completed clinical trial evaluating whether arterial partial pressure of oxygen influences the risk of anastomotic leakage after esophagec…
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CLINICAL_TRIALS trial_result · 2025-12-24Clinical Trial Update: Aceto-whitening in the Assessment of Gastrointestinal Neoplasia
Clinical trial update indicating completion of a study evaluating aceto-whitening for assessing neoplasia in Barrett's esophagus-related con…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: A Phase Ib Trial Evaluating the Safety and Activity of Neoadjuvant Combination of Tislelizumab Plus FLOT for Resectable Esophagogastric Adenocarcinoma [Phase 1]
Phase Ib trial evaluating the safety and activity of neoadjuvant tislelizumab plus the FLOT chemotherapy regimen in patients with resectable…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Assessment of a Minimally Invasive Collection Device for Molecular Analysis of Esophageal Samples [NA]
This ClinicalTrials.gov update describes a minimally invasive collection device designed for molecular analysis of esophageal samples, with …
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Propranolol in Combination With Pembrolizumab and Standard Chemotherapy for the Treatment of Unresectable Locally Advanced or Metastatic Esophageal or Gastroesophageal Junction Adenocarcinoma [Phase 2]
Phase 2 clinical trial evaluating propranolol in combination with pembrolizumab and standard chemotherapy for unresectable or metastatic eso…
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CLINICAL_TRIALS trial_result · 2025-12-15Clinical Trial Update: A Study of SGN-B6A in Chinese Participants With Advanced Solid Tumors [Phase 1]
A Phase 1 study of SGN-B6A in Chinese participants with advanced solid tumors has completed, reporting safety and preliminary activity acros…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Barrett's Esophagitis in Anorexia Nervosa Binge/Purge Subtype
Clinical trial update examining Barrett's esophagus in individuals with anorexia nervosa binge/purge subtype; the study is currently recruit…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: AUGMENTED RESPONSE OF VOLATILE BIOMARKERS IN THE ASSESSMENT OF OESOPHAGOGASTRIC CANCER (AROMA2)
A ClinicalTrials.gov entry for the AROMA2 study examines whether volatile biomarker profiles can augment assessment of esophagogastric cance…
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CLINICAL_TRIALS withdrawal · 2025-11-28Clinical Trial Update: (VELA) Study of BLU-222 in Advanced Solid Tumors [Phase 1]
A Phase 1 study of BLU-222 in advanced solid tumors has been terminated.
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CLINICAL_TRIALS research · 2025-11-28Clinical Trial Update: Testing Ivonescimab in Combination With Chemotherapy in Advanced or Metastatic Gastric/Gastroesophageal Adenocarcinoma [Phase 2]
Phase 2 clinical trial evaluating Ivonescimab in combination with chemotherapy for advanced or metastatic gastric/gastroesophageal adenocarc…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Surveillance vs. Endoscopic Therapy for Barrett's Esophagus With Low-grade Dysplasia [NA]
An ongoing clinical trial comparing surveillance versus endoscopic therapy for Barrett's esophagus with low-grade dysplasia. The study is cu…
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CLINICAL_TRIALS research · 2025-11-13Clinical Trial Update: Multi-Site Detection of Barrett's Esophagus in Patients Without Chronic GERD Symptoms [NA]
A multi-site clinical trial is investigating detection of Barrett's esophagus in patients without chronic GERD symptoms; recruitment is ongo…
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CLINICAL_TRIALS trial_result · 2025-11-05Clinical Trial Update: A Phase II Trial to Evaluate the Effect of Itraconazole on Pathologic Complete Response Rates in Resectable Esophageal Cancer [Phase 2]
Phase II trial evaluating the effect of itraconazole on pathologic complete response rates in resectable esophageal cancer is currently recr…