Esophageal Adenocarcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: Tucatinib, Trastuzumab, Ramucirumab, and Paclitaxel Versus Paclitaxel and Ramucirumab in Previously Treated HER2+ Gastroesophageal Cancer [Phase 2, Phase 3]
Clinical trial update reporting results from a Phase 2/3 study of tucatinib + trastuzumab + ramucirumab + paclitaxel vs paclitaxel + ramucir…
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CLINICAL_TRIALS trial_result · 2025-01-16Clinical Trial Update: Study to Test the Safety and Tolerability of PF-07062119 in Patients With Selected Advanced or Metastatic Gastrointestinal Tumors. [Phase 1]
A Phase 1 study of PF-07062119 in selected advanced or metastatic gastrointestinal tumors was terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2024-11-14Clinical Trial Update: Safety and Activity of IMAB362 in Combination With Zoledronic Acid and Interleukin-2 in CLDN18.2-positive Gastric Cancer [Phase 1]
Phase 1 study assessing safety and activity of IMAB362 (zolbetuximab) in combination with zoledronic acid and interleukin-2 in CLDN18.2-posi…
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CLINICAL_TRIALS trial_result · 2024-11-08Clinical Trial Update: Rapid Assessment of Esophageal Adenocarcinoma Risk Test [NA]
A terminated Columbia University clinical trial evaluated a rapid risk-assessment test for esophageal adenocarcinoma in individuals with Bar…
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CLINICAL_TRIALS trial_result · 2024-10-23Clinical Trial Update: Study of INBRX-105 and INBRX-105 With Pembrolizumab in Patients With Solid Tumors Including Head and Neck Cancer [Phase 1]
This Phase 1 trial update reports termination of the INBRX-105 in combination with pembrolizumab across multiple solid tumors, including hea…
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CLINICAL_TRIALS trial_result · 2024-10-02Clinical Trial Update: Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT141 in Patients With Unresectable or Metastatic CLDN18.2-positive Gastric, Pancreatic, Ovarian and Biliary Tract Tumors [Phase 1, Phase 2]
Phase 1/2 trial of BNT141 in CLDN18.2-positive gastric, pancreatic, ovarian, and biliary tract cancers. The study was terminated and results…
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CLINICAL_TRIALS trial_result · 2024-08-16Clinical Trial Update: NT-I7 in Combination With Nivolumab in Advanced Gastric, Gastro-Esophageal Junction or Esophageal Adenocarcinoma [Phase 1]
A Phase 1 trial of NT-I7 in combination with nivolumab for advanced gastric, gastroesophageal junction, or esophageal adenocarcinoma has bee…
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CLINICAL_TRIALS trial_result · 2024-07-18Clinical Trial Update: M6620 Plus Standard Treatment in Oesophageal and Other Cancer [Phase 1]
Phase 1 trial evaluating M6620 in combination with standard treatment for esophageal cancer (esophageal adenocarcinoma and esophageal squamo…
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CLINICAL_TRIALS trial_result · 2024-05-20Clinical Trial Update: Phase II Trial of Neoadjuvant Pembrolizumab for Patients With Early Stage Gastroesophageal Adenocarcinoma [Phase 2]
Phase II neoadjuvant pembrolizumab trial for early-stage gastroesophageal junction, gastric, and esophageal adenocarcinoma has been terminat…
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CLINICAL_TRIALS trial_result · 2024-05-10Clinical Trial Update: A Liquid Biopsy for High-risk Pre-cancer Screening of Esophageal Adenocarcinoma
This clinical trial evaluating a liquid biopsy for high-risk pre-cancer screening of esophageal adenocarcinoma has completed.
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CLINICAL_TRIALS trial_result · 2024-05-02Clinical Trial Update: Study of Pembrolizumab in Locally Advanced Esophageal Adenocarcinoma [Phase 2]
A Phase 2 clinical trial evaluating pembrolizumab in locally advanced esophageal adenocarcinoma has posted results.
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CLINICAL_TRIALS trial_result · 2024-03-15Clinical Trial Update: Multiorgan Metabolic Imaging Response Assessment of Abemaciclib [Phase 2]
Phase 2 trial update evaluating multiorgan metabolic imaging response assessment of abemaciclib.
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CLINICAL_TRIALS trial_result · 2024-01-18Clinical Trial Update: Use of Trifluridine/Tipiracil and Oxaliplatin as Induction Chemotherapy for the Treatment of Resectable Esophageal or Gastroesophageal Junction (GEJ) Adenocarcinoma [Phase 2]
Phase 2 trial evaluating induction chemotherapy with trifluridine/tipiracil and oxaliplatin for resectable esophageal or gastroesophageal ju…
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CLINICAL_TRIALS trial_result · 2024-01-08Clinical Trial Update: FOLFOX-6 Induction Chemotherapy Followed by Esophagectomy and Post-operative Chemoradiotherapy in Patients With Esophageal Adenocarcinoma [Phase 2]
Phase 2 clinical trial of FOLFOX-6 induction chemotherapy followed by esophagectomy and post-operative chemoradiotherapy for esophageal aden…
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CLINICAL_TRIALS trial_result · 2023-12-19Clinical Trial Update: Trial of mFOLFOX6 + Trastuzumab + Avelumab in Gastric and Esophageal Adenocarcinomas [Phase 2]
Phase 2 trial of mFOLFOX6 plus trastuzumab and avelumab in gastric and esophageal adenocarcinoma has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-11-03Clinical Trial Update: Evaluate Esophageal Reinforcement With ACell MatriStem Surgical Matrix: A Degradable Biologic Scaffold Material [Phase 2]
Phase 2 clinical trial evaluating esophageal reinforcement using a degradable Biologic Scaffold (ACell MatriStem) for esophageal adenocarcin…
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CLINICAL_TRIALS trial_result · 2023-07-10Clinical Trial Update: Taladegib, Paclitaxel, Carboplatin, and Radiation Therapy in Treating Patients With Localized Esophageal or Gastroesophageal Junction Cancer [Phase 1, Phase 2]
Phase 1/2 trial investigating taladegib with paclitaxel, carboplatin, and radiation therapy for localized esophageal or gastroesophageal jun…
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CLINICAL_TRIALS trial_result · 2023-05-01Clinical Trial Update: Aspirin in Preventing Disease Recurrence in Patients With Barrett Esophagus After Successful Elimination by Radiofrequency Ablation [Phase 2]
A Phase 2 clinical trial investigates whether aspirin reduces recurrence of Barrett esophagus or progression to esophageal adenocarcinoma af…
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CLINICAL_TRIALS trial_result · 2023-02-01Clinical Trial Update: Rucaparib Plus Ramucirumab With or Without Nivolumab in Advanced Gastric and Esophageal Adenocarcinoma [Phase 1, Phase 2]
Clinical trial update for a combination therapy (rucaparib + ramucirumab with or without nivolumab) in advanced gastric and esophageal adeno…
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CLINICAL_TRIALS trial_result · 2022-06-30Clinical Trial Update: Pembrolizumab and Palliative Radiation Therapy in Treating Patients With Metastatic Esophagus, Stomach, or Gastroesophageal Junction Cancer [Phase 2]
A Phase 2 trial evaluating pembrolizumab combined with palliative radiation therapy in patients with metastatic cancers of the esophagus, st…
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CLINICAL_TRIALS trial_result · 2022-06-28Clinical Trial Update: Efficacy Study of Nivolumab Plus Ipilimumab or Nivolumab Plus Chemotherapy Against Chemotherapy in Stomach Cancer or Stomach/Esophagus Junction Cancer [Phase 3]
Phase 3 efficacy trial comparing nivolumab plus ipilimumab or nivolumab plus chemotherapy against standard chemotherapy in gastric cancer an…
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CLINICAL_TRIALS trial_result · 2022-06-24Clinical Trial Update: TRAstuzumab and Pertuzumab for HER2+ Resectable Oesophageal Cancer [Phase 3]
Phase 3 trial investigating trastuzumab and pertuzumab for HER2-positive resectable esophageal cancer (esophageal adenocarcinoma) is current…
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CLINICAL_TRIALS trial_result · 2021-10-01Clinical Trial Update: Study of Erlotinib and Chemotherapy for Unresectable or Metastatic Cancer of the Esophagus and Gastric Cardia [Phase 2]
Phase 2 clinical trial evaluating erlotinib with chemotherapy for unresectable or metastatic esophageal and gastric cardia adenocarcinoma co…
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CLINICAL_TRIALS trial_result · 2021-05-04Clinical Trial Update: Radiation Therapy, Paclitaxel, and Carboplatin With or Without Trastuzumab in Treating Patients With Esophageal Cancer [Phase 3]
Phase 3 trial evaluating radiation therapy with paclitaxel and carboplatin with or without trastuzumab in esophageal and gastroesophageal ju…
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CLINICAL_TRIALS trial_result · 2021-05-04Clinical Trial Update: Radiation Therapy, Paclitaxel, and Carboplatin With or Without Trastuzumab in Treating Patients With Esophageal Cancer [Phase 3]
Phase 3 trial evaluating radiation therapy with paclitaxel and carboplatin with or without trastuzumab in esophageal cancer (NCT01196390) ha…