Erdheim-chester Disease
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: DETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Young Adult Patients With BRAF V600 Mutation-Positive Cancers. [Phase 2, Phase 3]
The DETERMINE trial's Arm 07 is studying dabrafenib plus trametinib in patients with BRAF V600 mutation-positive cancers across age groups; …
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CLINICAL_TRIALS trial_result · 2025-11-24Clinical Trial Update: DETERMINE Trial Treatment Arm 05: Vemurafenib in Combination With Cobimetinib in Adult Patients With BRAF Positive Cancers. [Phase 2, Phase 3]
Phase 2/3 DETERMINE trial treatment arm 05 is evaluating the combination of vemurafenib and cobimetinib in adults with BRAF-positive cancers…
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CLINICAL_TRIALS trial_result · 2025-06-11Clinical Trial Update: Histiocytic Disorder Follow-up Study
A University of Alabama at Birmingham-sponsored clinical trial update indicates recruiting for a histiocytic disorder follow-up study, inclu…
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CLINICAL_TRIALS trial_result · 2025-04-25Clinical Trial Update: Lenalidomide for Adult Histiocyte Disorders [Phase 2]
Phase 2 trial results of lenalidomide in adults with Langerhans cell histiocytosis, Erdheim-Chester disease, and histiocytic sarcoma; the st…
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CLINICAL_TRIALS trial_result · 2024-07-19Clinical Trial Update: A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of HH2710 in Patient With Advanced Tumors [Phase 1, Phase 2]
Phase 1/2 study of HH2710 in patients with melanoma and other advanced tumors was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2023-08-08Clinical Trial Update: The Efficacy and Safety of HLX208 in Adult Langerhans Cell Histiocytosis (LCH) and Erdheim-Chester Disease (ECD) With BRAF V600E Mutation [Phase 2]
Phase 2 clinical trial evaluating HLX208 for adult Langerhans Cell Histiocytosis and Erdheim-Chester Disease with BRAF V600E mutation; curre…
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CLINICAL_TRIALS trial_result · 2021-06-07Clinical Trial Update: Dabrafenib and Trametinib in People With BRAF V600E Mutation Positive Lesions in Erdheim Chester Disease [Phase 2]
Phase 2 trial evaluating dabrafenib and trametinib in patients with Erdheim-Chester disease harboring BRAF V600E mutation has completed with…
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CLINICAL_TRIALS trial_result · 2016-10-28Clinical Trial Update: Long-term Outcome After Vemurafenib / BRAF Inhibitors Interruption in Erdheim-chester Disease
This clinical trial update reports on the long-term outcomes after interruption of vemurafenib, a BRAF inhibitor, in patients with Erdheim-C…
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CLINICAL_TRIALS trial_result · 2016-02-10Clinical Trial Update: Pilot Study of Tocilizumab in Patients With Erdheim-Chester Disease [Phase 2]
A Phase 2 pilot trial of tocilizumab for Erdheim-Chester disease has been terminated, with the update focusing on the study status rather th…