Ependymoma
📧 Sign up to get email alerts when something new happens for Ependymoma.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2026-08-18Clinical Trial Results: Immune Checkpoint Inhibitor Nivolumab in People With Recurrent Select Rare CNS Cancers [Phase 2]
Phase 2 trial of nivolumab for recurrent rare CNS cancers (including medulloblastoma and ependymoma) was terminated with results posted in 2…
-
CLINICAL_TRIALS trial_result · 2026-06-23Clinical Trial Results: Memantine for Prevention of Cognitive Late Effects in Pediatric Patients Receiving Cranial Radiation Therapy for Localized Brain Tumors [Phase 2]
Phase 2 clinical trial assessing memantine to prevent cognitive late effects in children receiving cranial radiation for localized brain tum…
-
CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Exploratory Study of Effects of Radiation Therapy in Pediatric Patients With Central Nervous System Tumors
An exploratory study evaluating the effects of radiation therapy in pediatric patients with central nervous system tumors; the study include…
-
CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors [Phase 1]
Phase 1 clinical trial evaluating B7-H3–specific CAR T cell therapy delivered locoregionally for diffuse intrinsic pontine glioma/diffuse mi…
-
CLINICAL_TRIALS trial_result · 2026-04-06Clinical Trial Update: Optune for Children With High-Grade Glioma or Ependymoma, and Optune With Radiation Therapy for Children With DIPG [NA]
This ClinicalTrials.gov entry reports ongoing pediatric trials of Optune (Tumor Treating Fields) for malignant glioma and ependymoma, and in…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2026-04-06Clinical Trial Update: HER2-specific Chimeric Antigen Receptor (CAR) T Cells for Children With Ependymoma [Phase 1]
A Phase 1 trial evaluating HER2-directed CAR T cells in pediatric patients with ependymoma.
-
CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 pediatric MATCH trial evaluating IDH1-mutant tumors for response to ivosidenib; results for recurrent and refractory solid tumors, l…
-
CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: Rare CNS Tumors Outcomes &Risk
A National Cancer Institute clinical trial update reports outcomes and risks for rare central nervous system tumors, including meningioma, e…
-
CLINICAL_TRIALS trial_result · 2026-02-05Clinical Trial Update: Immunotherapy for Recurrent Ependymomas in Children Using Tumor Antigen Peptides With Imiquimod [Phase 1]
Phase 1 trial evaluating a tumor antigen peptide vaccine with imiquimod for children with recurrent ependymoma; the study status is terminat…
-
CLINICAL_TRIALS trial_result · 2026-02-05Clinical Trial Update: B7-H3.CD28Z.CART in CNS Neoplasms [Phase 1]
A Phase 1 clinical trial evaluating B7-H3.CD28Z.CART for central nervous system neoplasms is currently not yet recruiting.
-
CLINICAL_TRIALS trial_result · 2026-01-08Clinical Trial Update: Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG [Phase 2]
Phase 2 pediatric trial evaluating indoximod with chemotherapy and radiation for relapsed brain tumors or newly diagnosed diffuse intrinsic …
-
CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: EGFR806-specific CAR T Cell Locoregional Immunotherapy for EGFR-positive Recurrent or Refractory Pediatric CNS Tumors [Phase 1]
Phase 1 trial evaluating locoregional EGFR806-specific CAR T cells for EGFR-positive pediatric CNS tumors. The study status is completed.
-
CLINICAL_TRIALS trial_result · 2025-11-12Clinical Trial Update: A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer [Phase 1, Phase 2]
This document details an ongoing Phase 1/2 clinical trial evaluating cobolimab in combination with dostarlimab in pediatric and young adult …
-
CLINICAL_TRIALS trial_result · 2025-11-06Clinical Trial Update: Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial [Phase 2]
This update reports on a Phase 2 pediatric MATCH trial evaluating selpercatinib for patients with activating RET gene alterations across adv…
-
CLINICAL_TRIALS trial_result · 2025-10-16Clinical Trial Update: Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 pediatric MATCH trial evaluating larotrectinib in patients with NTRK gene fusions has posted results; the study remains active but n…
-
CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: Pharmacoscopy for Patients With Refractory Primary Brain Tumors [Phase 2]
Phase 2 clinical trial update for pharmacoscopy in patients with refractory primary brain tumors, currently not yet recruiting.
-
CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: Fluorine F 18 Fluorodopa-Labeled PET Scan in Planning Surgery and Radiation Therapy in Treating Patients With Newly Diagnosed High- or Low-Grade Malignant Glioma [EARLY_Phase 1]
Early-phase study evaluating the use of 18F-FDOPA PET imaging to plan surgery and radiation therapy for adults with newly diagnosed malignan…
-
CLINICAL_TRIALS trial_result · 2025-07-30Clinical Trial Update: Prospective Evaluation of AI R&D Tool in Adult Glioma and Other Primary Brain Tumours (PEAR-GLIO)
The PEAR-GLIO trial evaluating an AI R&D tool for adult gliomas and other primary brain tumors has been terminated.
-
CLINICAL_TRIALS trial_result · 2025-07-08Clinical Trial Update: HUMC 1612: Optune NovoTTF-200A System [Phase 1]
Phase 1 clinical trial update for HUMC 1612 evaluating the Optune NovoTTF-200A System in high-grade glioma and ependymoma; status shows comp…
-
CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: Immune Checkpoint Inhibitor Nivolumab in People With Recurrent Select Rare CNS Cancers [Phase 2]
A Phase 2 trial of nivolumab in patients with recurrent select rare CNS cancers (medulloblastoma, ependymoma, pineal region tumors, choroid …
-
CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: Proton Radiotherapy for Pediatric Brain Tumors Requiring Partial Brain Irradiation [Phase 2]
Phase 2 clinical trial evaluating proton radiotherapy for pediatric brain tumors requiring partial brain irradiation has completed enrollmen…
-
CLINICAL_TRIALS trial_result · 2025-04-22Clinical Trial Update: Trial of Selumetinib in Patients With Neurofibromatosis Type II Related Tumors [Phase 2]
Phase 2 trial of selumetinib in Neurofibromatosis type II–related tumors was terminated, with results posted in 2025; the study included ves…
-
CLINICAL_TRIALS trial_result · 2025-04-08Clinical Trial Update: Infusion of 5-Azacytidine (5-AZA) Into the Fourth Ventricle in Patients With Recurrent Posterior Fossa Ependymoma [Phase 1]
Phase 1 study assessing intraventricular infusion of 5-azacytidine for recurrent posterior fossa ependymoma has completed.
-
CLINICAL_TRIALS trial_result · 2025-03-03Clinical Trial Update: Combination Intraventricular Chemotherapy Pilot Study: 5-Azacytidine (5-AZA) and Trastuzumab Infusions Into the Fourth Ventricle or Resection Cavity in Children and Adults with Recurrent or Residual Posterior Fossa Ependymoma [EARLY_Phase 1]
Early-phase study evaluating intraventricular combination therapy with azacitidine and trastuzumab for recurrent or residual posterior fossa…
-
CLINICAL_TRIALS trial_result · 2024-11-12Clinical Trial Update: A Trial of Surgery and Fractionated Re-Irradiation for Recurrent Ependymoma [Phase 2]
Phase 2 trial from St. Jude evaluating surgery followed by fractionated re-irradiation for recurrent ependymoma; results posted on 2024-11-1…