Ebola Virus Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-12-08Clinical Trial Update: A Study to Evaluate the Safety and Immunogenicity of Heterologous Prime-Boost Ebola Vaccine Regimens in Healthy Participants [Phase 1]
This Phase 1 trial evaluated the safety and immunogenicity of heterologous prime-boost Ebola vaccine regimens (ChAd3-EBO-Z prime with MVA-BN…
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CLINICAL_TRIALS trial_result · 2016-09-01Clinical Trial Update: A Clinical Trial to Evaluate the Recombinant Human Type5 Adenovirus Vector Based Ebola Virus Disease Vaccine [Phase 2]
This clinical trial update reports the completion of a Phase 2 evaluation of a recombinant human adenovirus type 5 vector–based Ebola vaccin…
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CLINICAL_TRIALS trial_result · 2016-07-07Clinical Trial Update: A Phase 1 Study to Evaluate the Safety, Tolerability and Pharmacokinetics of BCX4430 [Phase 1]
Phase 1 study evaluating safety, tolerability, and pharmacokinetics of BCX4430 in filovirus infections, including Ebola virus disease, has c…
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CLINICAL_TRIALS research · 2016-04-14Clinical Trial Update: A Study to Find Out if the New Ebola Vaccine is Safe and Stimulates Immunity That Might Protect Adults in Kilifi, Kenya. [Phase 1]
Phase 1 trial update assessing safety and immunogenicity of a new Ebola vaccine in adults in Kilifi, Kenya.
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CLINICAL_TRIALS trial_result · 2016-02-09Clinical Trial Update: Phase I Trial to Assess the Safety, Tolerability and Immunogenicity of a Ebola Virus Vaccine [Phase 1]
This Phase I trial from Dalhousie University evaluated the safety, tolerability, and immunogenicity of an Ebola virus vaccine; the study has…
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CLINICAL_TRIALS trial_result · 2016-01-28Clinical Trial Update: A Clinical Trial on the Candidate Vaccine cAd3-EBOZ in Healthy Adults in Switzerland [Phase 1, Phase 2]
Phase 1/2 trial of the Ebola vaccine cAd3-EBOZ conducted in healthy adults in Switzerland has been completed.
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CLINICAL_TRIALS trial_result · 2016-01-26Clinical Trial Update: Efficacy of Favipiravir Against Severe Ebola Virus Disease [Phase 2]
A Phase 2 trial evaluating favipiravir for severe Ebola virus disease has completed, with the update focusing on its efficacy.
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CLINICAL_TRIALS trial_result · 2016-01-18Clinical Trial Update: Evaluation of the FilmArray BioThreat-E Test
A clinical trial evaluating the FilmArray BioThreat-E Test for Ebola Virus Disease has completed.
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CLINICAL_TRIALS trial_result · 2015-10-14Clinical Trial Update: A Booster Dose of Ad5-EBOV in Healthy Adults After Primary Immunization [Phase 1]
A Phase 1 trial evaluating a booster dose of the Ad5-EBOV Ebola vaccine in healthy adults after primary immunization has completed.
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CLINICAL_TRIALS withdrawal · 2015-10-06Clinical Trial Update: Clinical Study to Assess Efficacy and Safety of Amiodarone in Treating Patients With Ebola. Virus Disease (EVD) in Sierra Leone. EASE (EMERGENCY Amiodarone Study Against Ebola) [Phase 2, Phase 3]
The document reports that the Emergency NGO Onlus–sponsored EASE trial evaluating amiodarone for Ebola Virus Disease in Sierra Leone has bee…
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CLINICAL_TRIALS trial_result · 2015-08-28Clinical Trial Update: A Phase I Clinical Trial to Evaluate the Ebola Adenovirus Vector Vaccine (Ad5-EBOV) in Healthy Adults. [Phase 1]
A Phase I clinical trial evaluating the Ebola adenovirus vector vaccine Ad5-EBOV in healthy adults has completed, signaling early safety and…
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CLINICAL_TRIALS trial_result · 2015-08-07Clinical Trial Update: Safety, Tolerability and Pharmacokinetic First in Human (FIH) Study for Intravenous (IV) TKM-100802 [Phase 1]
Phase 1 intravenous study of TKM-100802 for Ebola virus disease reported safety, tolerability, and pharmacokinetics; the trial is terminated…
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CLINICAL_TRIALS trial_result · 2015-07-16Clinical Trial Update: A Phase I Trial to Evaluate Ad5-EBOV in Healthy Adult Africans in China. [Phase 1]
Phase I clinical trial evaluating the Ad5-EBOV Ebola vaccine in healthy adult Africans in China has completed.
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CLINICAL_TRIALS research · 2015-03-05Clinical Trial Update: Multiple Treatments for Ebola Virus Disease (EVD) [Phase 1, Phase 2]
This clinical trial registry entry lists Phase 1 and Phase 2 studies evaluating multiple treatments for Ebola Virus Disease, with the curren…
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CLINICAL_TRIALS withdrawal · 2015-02-02Clinical Trial Update: An Open-Label, Multicenter Study of the Safety and Anti Viral Activity of Brincidofovir (BCV, CMX001) for Ebola Virus Disease [Phase 2]
Open-label, multicenter Phase 2 study of Brincidofovir for Ebola virus disease has been withdrawn from further investigation.
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CLINICAL_TRIALS research · 2015-01-07Clinical Trial Update: Clinical Trial to Evaluate the Efficacy and Safety of Convalescent Plasma for Ebola Treatment [NA]
This document provides an update on a clinical trial evaluating the efficacy and safety of convalescent plasma for treating Ebola Virus Dise…
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EMA research · 2014-12-16Experimental Ebola treatments still at early stage of development
EMA notes that experimental Ebola treatments are still in early development stages and not yet proven to be effective or safe for routine us…
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EMA guidance · 2014-10-29EMA advises on development plan for GSK Ebola vaccine
EMA provides guidance on the development plan for GSK's Ebola vaccine, outlining recommended targets, study designs, and regulatory consider…
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EMA guidance · 2014-10-22EMA ready to start assessment of Ebola vaccines and treatments as soon as data are made available
EMA states readiness to start assessing Ebola vaccines and treatments as soon as regulatory data are submitted.
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EMA guidance · 2014-10-20Speeding up development of Ebola treatments and vaccines
EMA outlines strategies to accelerate development of Ebola treatments and vaccines, including prioritizing candidates, streamlined regulator…
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EMA guidance · 2014-09-26Ebola outbreak: EMA to review experimental medicines to support treatment decisions
EMA announces it will review experimental medicines to support treatment decisions during the Ebola outbreak.
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EMA guidance · 2014-09-04Medicines regulators to work together internationally to find innovative solutions to facilitate evaluation of and access to potential new medicines to counter Ebola outbreaks
European medicines regulators announce international collaboration to streamline evaluation and access to potential new medicines for Ebola …
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CLINICAL_TRIALS trial_result · 2014-01-09Clinical Trial Update: Safety, Tolerability and Pharmacokinetic First in Human (FIH) Study of Intravenous (IV) TKM-100201 Infusion [Phase 1]
This is a first-in-human Phase 1 study evaluating intravenous TKM-100201 for Ebola virus disease, focusing on safety, tolerability, and phar…
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CLINICAL_TRIALS trial_result · 2013-01-28Clinical Trial Update: Evaluating an Ebola and a Marburg Vaccine in Uganda [Phase 1]
A Phase 1 trial conducted in Uganda evaluated Ebola and Marburg vaccines. The study is completed.
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CLINICAL_TRIALS withdrawal · 2013-01-24Clinical Trial Update: A Study to Assess the Safety, Tolerability and Pharmacokinetics of AVI-7537 in Healthy Adult Volunteers [Phase 1]
A Phase 1 study of AVI-7537 in healthy adult volunteers for Ebola virus disease has been withdrawn.