Ebola Virus Disease
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CLINICAL_TRIALS research · 2026-06-17Clinical Trial Results: Immunogenicity of Recombinant Vesicular Stomatitis Vaccine for Ebola-Zaire (rVSV∆G-ZEBOV-GP Vaccine) [Phase 2]
Phase 2 trial results assessing the immunogenicity of the rVSV∆G-ZEBOV-GP Ebola vaccine in healthy volunteers.
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Impact of Delay Between Administration of Inmazeb Administration and Vaccination by Ervebo on Vaccine Immune Response on Healthy Volunteers [Phase 2]
Phase 2 clinical trial examining whether delaying Inmazeb (REGN-EB3) administration relative to Ervebo vaccination alters Ebola vaccine immu…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Immunology of Ebola Vaccine [Phase 2]
An update on a Phase 2 immunology study of an Ebola vaccine sponsored by Emory University; the trial is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: REVIVE (Response to the Ebola Virus Vaccine) [Phase 4]
This document provides an update on a Phase 4 clinical trial (REVIVE) evaluating a response to an Ebola virus vaccine sponsored by Tulane Un…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: R3470-3471-3479 (REGN-EB3) Expanded Access Protocol (EAP) for Treatment of Ebola Virus Disease
This document describes an Expanded Access Protocol for REGN-EB3 to treat Ebola Virus Disease. The protocol is currently available.
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: Natural History, Disease Progression, and Long-Term Neurologic Sequelae of Ebola Virus Disease (EVD) Survivors in PREVAIL III
This clinical trial update summarizes the natural history, disease progression, and long-term neurologic sequelae observed in Ebola virus di…
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: Immunity Induced by VSV-EBOV and Assessment of a Booster Dose in Individuals at Potential Occupational Risk for Exposure [Phase 3]
This clinical trial update concerns the VSV-EBOV Ebola vaccine. It includes assessment of a booster dose in individuals at potential occupat…
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CLINICAL_TRIALS research · 2025-03-18Clinical Trial Update: Safety and Immunogenicity of Ervebo® and Zabdeno® Booster Vaccines Against Ebola Virus Following Previous Vaccination with the Zabdeno/Mvabea® or Ervebo® Vaccine Schedules in DRC [Phase 3]
Phase 3 trial evaluating safety and immunogenicity of Ervebo and Zabdeno booster vaccines against Ebola virus in people previously vaccinate…
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CLINICAL_TRIALS research · 2024-12-17Clinical Trial Update: Open-Label Expanded Access for Ebola-Infected Patients to Receive Human MAb Ansuvimab As Therapeutic or for HR PEP
This document reports an open-label expanded access program for Ebola virus disease patients to receive the monoclonal antibody ansuvimab (E…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Safety and Immunogenicity of rVSVΔG-ZEBOV-GP Vaccination When Dosed Concurrently With mRNA COVID-19 Vaccine Booster Doses [Phase 4]
A Phase 4 clinical trial update evaluating the safety and immunogenicity of the Ebola vaccine Ervebo (rVSVΔG-ZEBOV-GP) when dosed concurrent…
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CLINICAL_TRIALS research · 2020-08-25Clinical Trial Update: International Multicenter Study of the Immunogenicity of Medicinal Product GamEvac-Combi [Phase 4]
Phase 4 international multicenter trial evaluating immunogenicity of GamEvac-Combi (Ebola vaccine) completed.
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CLINICAL_TRIALS research · 2016-04-14Clinical Trial Update: A Study to Find Out if the New Ebola Vaccine is Safe and Stimulates Immunity That Might Protect Adults in Kilifi, Kenya. [Phase 1]
Phase 1 trial update assessing safety and immunogenicity of a new Ebola vaccine in adults in Kilifi, Kenya.
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CLINICAL_TRIALS research · 2015-03-05Clinical Trial Update: Multiple Treatments for Ebola Virus Disease (EVD) [Phase 1, Phase 2]
This clinical trial registry entry lists Phase 1 and Phase 2 studies evaluating multiple treatments for Ebola Virus Disease, with the curren…
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CLINICAL_TRIALS research · 2015-01-07Clinical Trial Update: Clinical Trial to Evaluate the Efficacy and Safety of Convalescent Plasma for Ebola Treatment [NA]
This document provides an update on a clinical trial evaluating the efficacy and safety of convalescent plasma for treating Ebola Virus Dise…
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EMA research · 2014-12-16Experimental Ebola treatments still at early stage of development
EMA notes that experimental Ebola treatments are still in early development stages and not yet proven to be effective or safe for routine us…