Ebola Virus Disease
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CLINICAL_TRIALS trial_result · 2026-07-14Clinical Trial Results: Study to Evaluate the Immunogenicity and Safety of a Heterologous Vaccine Regimen Against Ebola [Phase 2]
Phase 2 trial assessing immunogenicity and safety of a heterologous Ebola vaccine regimen; results posted after completion.
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: Long-Term Neurologic and Neurocognitive Sequelae Following Pediatric Ebola Virus in Liberia
This completed clinical trial study reports on long-term neurologic and neurocognitive sequelae in pediatric Ebola survivors in Liberia.
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: Surveillance of Vaccine-induced Immunity Against Ebola in Previously Vaccinated Health Care Workers
A completed clinical trial update tracking the durability of vaccine-induced immunity against Ebola in healthcare workers who were previousl…
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CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: Evaluating the Live-Attenuated Human Parainfluenza Virus Type 3 Vectored Vaccine Candidate Expressing Ebolavirus Zaire Glycoprotein as the Sole Envelope Glycoprotein [Phase 1]
A Phase 1 clinical trial of a live-attenuated HPIV3 vectored vaccine expressing Ebola Zaire glycoprotein has been terminated; the Ebola Viru…
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: EBOla Post-Exposure Prophylaxis [Phase 3]
A Phase 3 trial evaluating post-exposure prophylaxis for Ebola virus disease is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-12-18Clinical Trial Update: A Phase I Study to Assess Ebola Vaccines cAd3-EBO Z and MVA-EBO Z [Phase 1]
The Phase I trial evaluating the Ebola vaccines cAd3-EBO Z and MVA-EBO Z conducted by the University of Oxford has been terminated.
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CLINICAL_TRIALS trial_result · 2025-11-18Clinical Trial Update: Efficacy of Favipiravir Against Ebola (JIKI) [Phase 2]
Phase 2 trial (JIKI) evaluating Favipiravir for Ebola virus disease has completed; the update summarizes the efficacy findings.
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CLINICAL_TRIALS trial_result · 2025-10-01Clinical Trial Update: Evaluation and Support to EVD Cured Patients and Their Contacts (Les Vainqueurs d'Ebola)
A completed clinical trial update from INSERM evaluating and providing support to Ebola virus disease survivors and their contacts.
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CLINICAL_TRIALS trial_result · 2025-07-29Clinical Trial Update: A Safety Trial to Test MVA-BN(R)-Filo and Ad26.ZEBOV Vaccines in Healthy Volunteers [Phase 1]
This update reports the completion of a Phase 1 safety trial evaluating MVA-BN Filo and Ad26.ZEBOV vaccines in healthy volunteers.
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CLINICAL_TRIALS trial_result · 2025-07-01Clinical Trial Update: Immunogenicity of Recombinant Vesicular Stomatitis Vaccine for Ebola-Zaire (rVSV[Delta]G-ZEBOV-GP) for Pre-Exposure Prophylaxis (PREP) in People at Potential Occupational Risk for Ebola Virus Exposure [Phase 2]
Phase 2 study assessing the immunogenicity of the rVSV-ZEBOV-GP Ebola vaccine for pre-exposure prophylaxis in individuals at potential occup…
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CLINICAL_TRIALS trial_result · 2025-06-22Clinical Trial Update: A Study to Evaluate the Immunogenicity, Safety and Tolerability of Ad26.ZEBOV and MVA-BN-Filo in Healthy Adult Participants [Phase 3]
Phase 3 study evaluating the immunogenicity, safety and tolerability of the Ebola vaccine regimen Ad26.ZEBOV prime followed by MVA-BN-Filo b…
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CLINICAL_TRIALS trial_result · 2025-05-11Clinical Trial Update: Ad26.ZEBOV, MVA-BN-Filo Vaccination in Children and Adults Previously Vaccinated With Control in the EBOVAC-Salone Study [Phase 2]
Phase 2 clinical trial update evaluating Ad26.ZEBOV and MVA-BN-Filo vaccines in children and adults previously vaccinated in the EBOVAC-Salo…
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CLINICAL_TRIALS trial_result · 2025-02-24Clinical Trial Update: Tolerance and Activity Evaluation of High Doses of Favipiravir Against Ebola Virus in the Semen [Phase 2]
A Phase 2 trial evaluated tolerability and antiviral activity of high-dose Favipiravir in semen of Ebola virus survivors; the study was term…
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: A Study of a 2-dose Ebola Vaccine Regimen of Ad26.ZEBOV Followed by MVA-BN-Filo in Healthy Pregnant Women [Phase 3]
A Phase 3 trial evaluating a two-dose Ebola vaccine regimen (Ad26.ZEBOV prime followed by MVA-BN-Filo boost) in healthy pregnant women has c…
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CLINICAL_TRIALS trial_result · 2024-01-02Clinical Trial Update: Long-term Safety Follow-up of Participants Exposed to the Candidate Ebola Vaccines Ad26.ZEBOV and/or MVA-BN-Filo [Phase 3]
Long-term safety follow-up results for Ebola vaccine candidates Ad26.ZEBOV and/or MVA-BN-Filo from a Phase 3 study have been posted after te…
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CLINICAL_TRIALS trial_result · 2023-12-13Clinical Trial Update: Ad26.ZEBOV Booster in Children Previously Vaccinated With Ad26.ZEBOV and MVA-BN-Filo (EBOVAC Booster Study) [Phase 2]
Phase 2 trial of Ad26.ZEBOV booster in children previously vaccinated shows completed status with posted results.
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CLINICAL_TRIALS trial_result · 2023-06-22Clinical Trial Update: A Study of 2-dose Vaccination Regimen of Ad26.ZEBOV and MVA-BN-Filo in Infants [Phase 2]
Results from a Phase 2 study of a two-dose Ad26.ZEBOV and MVA-BN-Filo vaccination regimen in infants have been completed and posted.
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CLINICAL_TRIALS trial_result · 2023-05-17Clinical Trial Update: A Study of 2-dose Vaccine Regimen Using 3 Consecutive Lots of Ad26.ZEBOV and MVA-BN-Filo in Adult Participants [Phase 3]
A Phase 3 study evaluating a two-dose vaccine regimen using Ad26.ZEBOV and MVA-BN-Filo in adults with Ebola has completed and results were p…
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CLINICAL_TRIALS trial_result · 2023-04-20Clinical Trial Update: Safety and Immunogenicity of the rVSVΔG-ZEBOV-GP Ebola Virus Vaccine Candidate in Children Living in Lambaréné, Gabon [Phase 1, Phase 2]
Phase 1/2 trial assessing safety and immunogenicity of the rVSVΔG-ZEBOV-GP Ebola vaccine candidate in children in Gabon has completed.
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CLINICAL_TRIALS trial_result · 2023-02-21Clinical Trial Update: Ad26.ZEBOV Booster in HIV+ Adults Previously Vaccinated With Ad26.ZEBOV/MVA-BN-Filo (EBOVAC HIV+ Booster Study) [Phase 2]
Phase 2 trial update on Ad26.ZEBOV booster given to HIV-positive adults previously vaccinated with Ad26.ZEBOV/MVA-BN-Filo; study completed.
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CLINICAL_TRIALS trial_result · 2023-01-04Clinical Trial Update: Study to Evaluate the Immunogenicity and Safety of a Heterologous Vaccine Regimen Against Ebola [Phase 2]
Phase 2 trial evaluating immunogenicity and safety of a heterologous vaccine regimen for Ebola Virus Disease has completed.
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CLINICAL_TRIALS trial_result · 2022-09-28Clinical Trial Update: Partnership for Research on Ebola VACcinations [Phase 2]
Phase 2 clinical trial results for an Ebola vaccine collaboration have been completed and results posted.
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CLINICAL_TRIALS trial_result · 2022-07-18Clinical Trial Update: Staged Phase 3 Study to Assess the Safety and Immunogenicity of Ebola Candidate Vaccines Ad26.ZEBOV and MVA-BN-Filo [Phase 3]
Phase 3 study assessing safety and immunogenicity of Ebola vaccine candidates Ad26.ZEBOV and MVA-BN-Filo completed; results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-03-07Clinical Trial Update: Safety, Tolerability and Immunogenicity Study of 3 Prime-boost Regimens for Ebola Vaccines Ad26.ZEBOV/MVA-BN-Filo in Healthy Adults, Children and Human Immunodeficiency Virus Positive (HIV+) Adults [Phase 2]
Phase 2 safety, tolerability, and immunogenicity study of three prime-boost regimens for Ebola vaccines Ad26.ZEBOV/MVA-BN-Filo in healthy ad…
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CLINICAL_TRIALS trial_result · 2022-02-18Clinical Trial Update: Safety, Tolerability and Immunogenicity Study of 2-dose Heterologous Regimens for Ebola Vaccines Ad26.ZEBOV/MVA-BN-Filo [Phase 2]
This Phase 2 trial evaluated safety, tolerability and immunogenicity of two-dose heterologous Ebola vaccine regimens using Ad26.ZEBOV/MVA-BN…