Ebola Virus Disease
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CLINICAL_TRIALS trial_result · 2017-05-30Clinical Trial Update: Phase I Trial to Assess the Safety, Tolerability and Immunogenicity of a Ebola Virus Vaccine (rVSVΔG-ZEBOV-GP) [Phase 1]
Phase I trial evaluating the safety, tolerability, and immunogenicity of the Ebola vaccine rVSVΔG-ZEBOV-GP.
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CLINICAL_TRIALS trial_result · 2017-04-04Clinical Trial Update: Trial to Evaluate Safety and Immunogenicity of an Ebola Zaire Vaccine in Healthy Adults [Phase 1]
Phase 1 clinical trial update assessing safety and immunogenicity of an Ebola Zaire vaccine in healthy adults.
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CLINICAL_TRIALS trial_result · 2017-02-01Clinical Trial Update: Evaluating the Safety of and Immune Response to a Human Parainfluenza Virus Type 3 Ebola Virus Vaccine (HPIV3-EbovZ GP) in Healthy Adults [Phase 1]
A Phase 1 trial in healthy adults evaluated the safety and immune response of the HPIV3-EbovZ GP Ebola vaccine, and the study has completed.
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CLINICAL_TRIALS trial_result · 2016-12-08Clinical Trial Update: A Study to Assess the Safety and Immunogenicity of Heterologous Prime-Boost Ebola Vaccine Regimens in Healthy Participants [Phase 1]
This Phase 1 trial evaluated the safety and immunogenicity of heterologous prime-boost Ebola vaccine regimens in healthy participants. The s…
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CLINICAL_TRIALS trial_result · 2016-12-08Clinical Trial Update: A Study to Evaluate the Safety and Immunogenicity of Heterologous Prime-Boost Ebola Vaccine Regimens in Healthy Participants [Phase 1]
This Phase 1 trial evaluated the safety and immunogenicity of heterologous prime-boost Ebola vaccine regimens (ChAd3-EBO-Z prime with MVA-BN…
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CLINICAL_TRIALS trial_result · 2016-09-01Clinical Trial Update: A Clinical Trial to Evaluate the Recombinant Human Type5 Adenovirus Vector Based Ebola Virus Disease Vaccine [Phase 2]
This clinical trial update reports the completion of a Phase 2 evaluation of a recombinant human adenovirus type 5 vector–based Ebola vaccin…
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CLINICAL_TRIALS trial_result · 2016-07-07Clinical Trial Update: A Phase 1 Study to Evaluate the Safety, Tolerability and Pharmacokinetics of BCX4430 [Phase 1]
Phase 1 study evaluating safety, tolerability, and pharmacokinetics of BCX4430 in filovirus infections, including Ebola virus disease, has c…
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CLINICAL_TRIALS trial_result · 2016-02-09Clinical Trial Update: Phase I Trial to Assess the Safety, Tolerability and Immunogenicity of a Ebola Virus Vaccine [Phase 1]
This Phase I trial from Dalhousie University evaluated the safety, tolerability, and immunogenicity of an Ebola virus vaccine; the study has…
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CLINICAL_TRIALS trial_result · 2016-01-28Clinical Trial Update: A Clinical Trial on the Candidate Vaccine cAd3-EBOZ in Healthy Adults in Switzerland [Phase 1, Phase 2]
Phase 1/2 trial of the Ebola vaccine cAd3-EBOZ conducted in healthy adults in Switzerland has been completed.
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CLINICAL_TRIALS trial_result · 2016-01-26Clinical Trial Update: Efficacy of Favipiravir Against Severe Ebola Virus Disease [Phase 2]
A Phase 2 trial evaluating favipiravir for severe Ebola virus disease has completed, with the update focusing on its efficacy.
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CLINICAL_TRIALS trial_result · 2016-01-18Clinical Trial Update: Evaluation of the FilmArray BioThreat-E Test
A clinical trial evaluating the FilmArray BioThreat-E Test for Ebola Virus Disease has completed.
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CLINICAL_TRIALS trial_result · 2015-10-14Clinical Trial Update: A Booster Dose of Ad5-EBOV in Healthy Adults After Primary Immunization [Phase 1]
A Phase 1 trial evaluating a booster dose of the Ad5-EBOV Ebola vaccine in healthy adults after primary immunization has completed.
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CLINICAL_TRIALS trial_result · 2015-08-28Clinical Trial Update: A Phase I Clinical Trial to Evaluate the Ebola Adenovirus Vector Vaccine (Ad5-EBOV) in Healthy Adults. [Phase 1]
A Phase I clinical trial evaluating the Ebola adenovirus vector vaccine Ad5-EBOV in healthy adults has completed, signaling early safety and…
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CLINICAL_TRIALS trial_result · 2015-08-07Clinical Trial Update: Safety, Tolerability and Pharmacokinetic First in Human (FIH) Study for Intravenous (IV) TKM-100802 [Phase 1]
Phase 1 intravenous study of TKM-100802 for Ebola virus disease reported safety, tolerability, and pharmacokinetics; the trial is terminated…
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CLINICAL_TRIALS trial_result · 2015-07-16Clinical Trial Update: A Phase I Trial to Evaluate Ad5-EBOV in Healthy Adult Africans in China. [Phase 1]
Phase I clinical trial evaluating the Ad5-EBOV Ebola vaccine in healthy adult Africans in China has completed.
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CLINICAL_TRIALS trial_result · 2014-01-09Clinical Trial Update: Safety, Tolerability and Pharmacokinetic First in Human (FIH) Study of Intravenous (IV) TKM-100201 Infusion [Phase 1]
This is a first-in-human Phase 1 study evaluating intravenous TKM-100201 for Ebola virus disease, focusing on safety, tolerability, and phar…
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CLINICAL_TRIALS trial_result · 2013-01-28Clinical Trial Update: Evaluating an Ebola and a Marburg Vaccine in Uganda [Phase 1]
A Phase 1 trial conducted in Uganda evaluated Ebola and Marburg vaccines. The study is completed.
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CLINICAL_TRIALS trial_result · 2012-03-28Clinical Trial Update: Safety Study of Single Administration Post-Exposure Prophylaxis Treatment for Ebola Virus [Phase 1]
A Phase 1 safety study evaluating a single-administration post-exposure prophylaxis treatment for Ebola virus disease has completed.