Diffuse Midline Glioma H3 K27m-mutant

• CLINICAL_TRIALS trial_result · 2026-04-24
  Clinical Trial Update: Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astrocytoma [Phase 1]

  A Phase 1 trial evaluating Triapine in combination with radiation therapy for recurrent glioblastoma or astrocytoma has been suspended.

• CLINICAL_TRIALS trial_result · 2026-01-14
  Clinical Trial Update: A Study of the Safety, Dosing, and Delivery of NEO100 in Patients With Pediatric Brain Tumors [Phase 1]

  This Phase 1 clinical trial assesses the safety, dosing, and delivery of NEO100 in pediatric brain and CNS tumors and is not yet recruiting.

• CLINICAL_TRIALS trial_result · 2025-08-20
  Clinical Trial Update: Intermediate-size Expanded Access to ONC201 for Patients With H3 K27M-mutant and/or Midline Gliomas

  This update describes an intermediate-size expanded access program for ONC201 in patients with H3 K27M-mutant diffuse midline glioma. The tr…

• CLINICAL_TRIALS trial_result · 2025-01-22
  Clinical Trial Update: H3.3K27M Peptide Vaccine With Nivolumab for Children With Newly Diagnosed DIPG and Other Gliomas [Phase 1, Phase 2]

  Clinical trial results update for a combined H3.3K27M peptide vaccine and nivolumab in children with newly diagnosed Diffuse Intrinsic Ponti…

• CLINICAL_TRIALS trial_result · 2024-12-20
  Clinical Trial Update: A Study of BXQ-350 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) or Diffuse Midline Glioma (DMG) [Phase 1]

  Phase 1 trial evaluating BXQ-350 in children with newly diagnosed diffuse intrinsic pontine glioma and diffuse midline glioma (H3 K27M-mutan…

• Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
• CLINICAL_TRIALS trial_result · 2024-01-03
  Clinical Trial Update: Adavosertib and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas [Phase 1]

  Phase 1 trial evaluating adavosertib with local radiation in children with newly diagnosed diffuse intrinsic pontine glioma; results are pos…