Diffuse Large B-cell Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-05-20Clinical Trial Update: A Study of CC-97540, CD19-targeted NEX-T Chimeric Antigen Receptor (CAR) T Cells, in Subjects With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma [Phase 1]
This is a Phase 1 study update for CC-97540, a CD19-targeted NEX-T CAR T cell therapy, in relapsed or refractory B-cell non-Hodgkin lymphoma…
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CLINICAL_TRIALS trial_result · 2024-05-17Clinical Trial Update: Study to Evaluate the Efficacy and Tolerability of Debio 1562 in Combination With Rituximab in Participants With Relapsed and/or Refractory DLBCL and Other Forms of NHL [Phase 2]
Phase 2 study evaluating Debio 1562 in combination with Rituximab for relapsed/refractory Diffuse Large B-Cell Lymphoma and other B-cell non…
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CLINICAL_TRIALS research · 2024-05-17Clinical Trial Update: A Study to Evaluate Efficacy and Safety of Zanubrutinib With R-CHOP in Newly Diagnosed Non-GCB DLBCL Patients With Double Expression [Phase 2]
A Phase 2 clinical trial evaluating the combination of zanubrutinib with the R-CHOP regimen in newly diagnosed non-GCB Diffuse Large B-Cell …
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CLINICAL_TRIALS trial_result · 2024-05-13Clinical Trial Update: Lenalidomide Combined With R-CHOP(R2-CHOP) in Newly Diagnosed Double-expressor Diffuse Large B-Cell Lymphoma Patients [Phase 2]
Phase 2 trial evaluating lenalidomide combined with R-CHOP (R2-CHOP) for newly diagnosed double-expressor diffuse large B-cell lymphoma has …
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CLINICAL_TRIALS trial_result · 2024-05-13Clinical Trial Update: A Study of ICP-022 in Patients With R/R DLBCL [Phase 2]
Phase 2 study of ICP-022 in relapsed/refractory diffuse large B cell lymphoma has completed.
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CLINICAL_TRIALS research · 2024-05-13Clinical Trial Update: Fludarabine and Cyclophosphamide With or Without Rituximab Before CD19 Chimeric Antigen Receptor T Cells for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma [Phase 1]
This Phase 1 trial investigates fludarabine and cyclophosphamide with or without rituximab as a lymphodepletion regimen before CD19 CAR-T ce…
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CLINICAL_TRIALS trial_result · 2024-05-13Clinical Trial Update: Reduction of MTX Levels After Glucarpidase Treatment in DLBCL Patients at Risk of CNS [Phase 2]
This Phase 2 trial investigates reduction of methotrexate levels after glucarpidase treatment in Diffuse Large B-Cell Lymphoma patients at r…
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CLINICAL_TRIALS trial_result · 2024-05-02Clinical Trial Update: Duvelisib and Nivolumab in Treating Patients With Richter Syndrome or Transformed Follicular Lymphoma [Phase 1]
A Phase 1 study evaluating the safety and preliminary efficacy of the combination of duvelisib and nivolumab in patients with Richter syndro…
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CLINICAL_TRIALS trial_result · 2024-04-30Clinical Trial Update: Phase 2 Study of Plamotamab Combined With Tafasitamab Plus Lenalidomide Versus Tafasitamab Plus Lenalidomide in Relapsed or Refractory (R/R) Diffuse Large-cell B-cell Lymphoma (DLBCL) [Phase 2]
Phase 2 trial evaluating plamotamab plus tafasitamab and lenalidomide versus tafasitamab and lenalidomide in relapsed or refractory diffuse …
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CLINICAL_TRIALS research · 2024-04-30Clinical Trial Update: Care Pathway and Associated Costs of Patients Treated With CAR T-cells Based on SNDS Data
This study updates care pathways and costs for patients treated with CAR T-cell therapies using SNDS data.
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CLINICAL_TRIALS withdrawal · 2024-04-25Clinical Trial Update: CpG-STAT3 siRNA CAS3/SS3 and Localized Radiation Therapy for the Treatment of Relapsed/Refractory B-Cell NHL [Phase 1]
A Phase 1 trial investigating CpG-STAT3 siRNA CAS3/SS3 with localized radiation for relapsed/refractory B-cell non-Hodgkin lymphomas has bee…
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CLINICAL_TRIALS trial_result · 2024-04-18Clinical Trial Update: Study of Efficacy and Safety of CTL019 in Adult DLBCL Patients [Phase 2]
Phase 2 trial update on CTL019 (tisagenlecleucel) for adult diffuse large B-cell lymphoma; results posted after completion.
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CLINICAL_TRIALS trial_result · 2024-04-09Clinical Trial Update: Trial on Lenalidomide Given as Maintenance Therapy for Relapsed Diffuse Large B Cell Lymphoma [Phase 2]
Phase 2 trial evaluating lenalidomide as maintenance therapy in relapsed diffuse large B-cell lymphoma has completed with results posted.
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CLINICAL_TRIALS trial_result · 2024-04-09Clinical Trial Update: Maintenance Hormonal Therapy and DLBCL [Phase 2, Phase 3]
Phase 2/3 clinical trial update evaluating maintenance hormonal therapy for Diffuse Large B-Cell Lymphoma.
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CLINICAL_TRIALS trial_result · 2024-03-27Clinical Trial Update: R-DA-EDOCH Versus R-CEOP90, With/Without Upfront Auto-HSCT in Young Patients With High-risk DLBCL [Phase 3]
Phase 3 trial comparing R-DA-EDOCH versus R-CEOP90 with/without upfront autologous HSCT in young high-risk diffuse large B-cell lymphoma pat…
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CLINICAL_TRIALS trial_result · 2024-03-25Clinical Trial Update: A Study Evaluating the Safety and Efficacy of Glofitamab or Mosunetuzumab in Combination With Gemcitabine Plus Oxaliplatin in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma and High-Grade Large B-Cell Lymphoma [Phase 1]
Phase 1 study evaluating safety and efficacy of Glofitamab or Mosunetuzumab with gemcitabine plus oxaliplatin in relapsed/refractory B-cell …
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CLINICAL_TRIALS trial_result · 2024-03-22Clinical Trial Update: Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of AMG 562 in Subjects With r/r Diffuse Large B-cell Lymphoma, Mantle Cell Lymphoma, or Follicular Lymphoma [Phase 1]
Phase 1 trial evaluating AMG 562 in relapsed/refractory DLBCL, MCL, or follicular lymphoma was terminated; results posted.
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CLINICAL_TRIALS trial_result · 2024-03-13Clinical Trial Update: Zanubrutinib+Lenalidomide+R-ICE in Relapsed/Refractory DLBCL [Phase 2]
Phase 2 clinical trial evaluating zanubrutinib, lenalidomide, and R-ICE in relapsed/refractory diffuse large B-cell lymphoma.
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CLINICAL_TRIALS trial_result · 2024-03-08Clinical Trial Update: Study of Mocetinostat in Selected Patients With Mutations of Acetyltransferase Genes in Relapsed and Refractory Diffuse Large B-Cell Lymphoma and Follicular Lymphoma [Phase 1, Phase 2]
Clinical trial of mocetinostat in relapsed/refractory diffuse large B-cell lymphoma and follicular lymphoma terminated; results posted.
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CLINICAL_TRIALS trial_result · 2024-03-07Clinical Trial Update: Study of Effectiveness of Axicabtagene Ciloleucel Compared to Standard of Care Therapy in Patients With Relapsed/Refractory Diffuse Large B Cell Lymphoma [Phase 3]
Phase 3 study evaluating axicabtagene ciloleucel versus standard-of-care therapy in relapsed/refractory diffuse large B-cell lymphoma has co…
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CLINICAL_TRIALS trial_result · 2024-03-04Clinical Trial Update: Orelabrutinib Combined With R-CDOP for DLBCL Patients With High-risk of CNS Relapse Defined by CNS-IPI [Phase 2]
Phase 2 trial evaluating orelabrutinib combined with R-CDOP for high CNS-relapse risk DLBCL patients (CNS-IPI defined).
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CLINICAL_TRIALS trial_result · 2024-03-01Clinical Trial Update: A Phase 2 Study of NIR178 in Combination With PDR001 in Patients With Solid Tumors and Non-Hodgkin Lymphoma [Phase 2]
This Phase 2 trial evaluating NIR178 in combination with PDR001 across multiple solid tumors and non-Hodgkin lymphoma was terminated, with r…
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CLINICAL_TRIALS trial_result · 2024-02-26Clinical Trial Update: Clinical Trial to Evaluate R-COMP Versus R-CHOP in Newly Diagnosed Patients With Non-localised Diffuse Large B-cell Lymphoma (DLBCL)/Follicular Lymphoma Grade IIIb [Phase 2]
Phase 2 trial comparing R-COMP to R-CHOP in newly diagnosed non-localised DLBCL and Follicular Lymphoma Grade IIIb has completed.
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CLINICAL_TRIALS trial_result · 2024-02-20Clinical Trial Update: A Study Comparing the Efficacy and Safety of G-CHOP Versus R-CHOP in Untreated Diffuse Large B-cell Lymphoma Patients [Phase 3]
Phase 3 trial comparing G-CHOP to R-CHOP in untreated diffuse large B-cell lymphoma (DLBCL) with unknown status.
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CLINICAL_TRIALS trial_result · 2024-02-08Clinical Trial Update: Mitoxantrone Hydrochloride Liposome Injection in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL) [Phase 2]
Phase 2 clinical trial update for mitoxantrone hydrochloride liposome injection in relapsed/refractory diffuse large B-cell lymphoma.