Diffuse Large B-cell Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-11-21Clinical Trial Update: Safety Study of Rituximab (SC) Administered in Participants With CD20+ DLBCL or CD20+ Follicular NHL Grade 1 to 3A [Phase 3]
Results from a Phase 3 safety study of subcutaneous rituximab in CD20-positive diffuse large B-cell lymphoma or CD20-positive follicular lym…
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CLINICAL_TRIALS trial_result · 2024-10-28Clinical Trial Update: Oral Azacitidine Plus Salvage Chemotherapy in Relapsed/Refractory Diffuse Large B Cell Lymphoma [Phase 1]
Phase 1 trial evaluating the safety of combining oral azacitidine with salvage chemotherapy in patients with relapsed or refractory diffuse …
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CLINICAL_TRIALS trial_result · 2024-10-26Clinical Trial Update: Venetoclax and Selinexor in Treating Patients with Relapsed or Refractory High Risk Hematologic Malignancies [Phase 1]
This Phase 1 trial evaluated the combination of venetoclax and selinexor in relapsed or refractory high-risk hematologic malignancies, inclu…
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CLINICAL_TRIALS trial_result · 2024-10-22Clinical Trial Update: Zanubrutinib Combined With BEAM for ASCT in Relapsed and Refractory DLBCL [Phase 2]
Phase 2 clinical trial evaluating zanubrutinib in combination with BEAM conditioning for autologous stem cell transplantation in relapsed or…
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CLINICAL_TRIALS trial_result · 2024-10-22Clinical Trial Update: Selinexor Combined With BEAM for ASCT in R/R DLBCL With MYC Positive [Phase 2]
A Phase 2 clinical trial is evaluating selinexor in combination with BEAM conditioning for autologous stem cell transplantation in relapsed/…
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CLINICAL_TRIALS trial_result · 2024-10-16Clinical Trial Update: Nivolumab With or Without Varlilumab in Treating Patients With Relapsed or Refractory Aggressive B-cell Lymphomas [Phase 2]
Phase 2 trial evaluating nivolumab with or without varlilumab in relapsed or refractory aggressive B-cell lymphomas, including multiple DLBC…
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CLINICAL_TRIALS trial_result · 2024-10-16Clinical Trial Update: Phase Ib Study to Assess Safety and Preliminary Efficacy of Tafasitamab or Tafasitamab Plus Lenalidomide in Addition to R-CHOP in Patients With Newly Diagnosed DLBCL [Phase 1]
Phase Ib trial assessing safety and preliminary efficacy of tafasitamab alone or with lenalidomide added to R-CHOP in newly diagnosed Diffus…
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CLINICAL_TRIALS trial_result · 2024-10-10Clinical Trial Update: Ibrutinib in Patients With Refractory/Relapsed Non-GCB Diffuse Large B-cell Lymphoma Non-candidates to ASCT [Phase 2]
Phase 2 trial of ibrutinib in patients with refractory/relapsed non-GCB diffuse large B-cell lymphoma who are non-candidates for autologous …
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CLINICAL_TRIALS trial_result · 2024-09-23Clinical Trial Update: A Study of ABT-199 Plus Ibrutinib and Rituximab in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma [Phase 1]
Phase 1 study evaluating ABT-199 (venetoclax) in combination with ibrutinib and rituximab for relapsed/refractory diffuse large B-cell lymph…
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CLINICAL_TRIALS trial_result · 2024-09-23Clinical Trial Update: Comparison of Point-of-care Produced CAR T-cell with Commercial CAR T-cells in Patients with R/R LBCL [Phase 2]
Phase 2 clinical trial update evaluating point-of-care produced CAR T-cells versus commercial CAR T-cells in patients with relapsed/refracto…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: A Phase I/II Study of Lenalidomide and Obinutuzumab With CHOP for Diffuse Large B Cell Lymphoma [Phase 1, Phase 2]
Phase I/II study evaluating lenalidomide and obinutuzumab added to CHOP chemotherapy for diffuse large B-cell lymphoma has completed enrollm…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: A Randomized, Multicenter, Phase III Trial Comparing Treatment With R-mini-CHOP With R-mini-CHP + Polatuzumab Vedotin in Patients With Diffuse Large Cell B Cell Lymphoma [Phase 3]
A randomized Phase III trial compares R-mini-CHOP with R-mini-CHP plus polatuzumab vedotin in diffuse large B-cell lymphoma; the study is cu…
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CLINICAL_TRIALS trial_result · 2024-09-04Clinical Trial Update: Fatigue Reduction Diet in Lymphoma Survivors [NA]
A clinical trial evaluating a Fatigue Reduction Diet for survivors of diffuse large B-cell lymphoma has completed.
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CLINICAL_TRIALS trial_result · 2024-09-03Clinical Trial Update: A Clinical Trial to Learn About the Study Medicine Called Maplirpacept (PF-07901801), Alone and When Used in Combination With Other Medicines to Treat Participants With Advanced Hematological Malignancies, Including Lymphoma, Leukemia and Multiple Myeloma [Phase 1]
Pfizer's Phase 1 trial of Maplirpacept (PF-07901801) in advanced hematologic malignancies, including diffuse large B-cell lymphoma, acute my…
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CLINICAL_TRIALS trial_result · 2024-08-26Clinical Trial Update: Polatuzumab Vedotin, Rituximab, Ifosfamide, Carboplatin, and Etoposide (PolaR-ICE) as Initial Salvage Therapy for the Treatment of Relapsed/Refractory Diffuse Large B-Cell Lymphoma [Phase 2]
Phase 2 study evaluating PolaR-ICE (polatuzumab vedotin, rituximab, ifosfamide, carboplatin, etoposide) as initial salvage therapy for relap…
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CLINICAL_TRIALS trial_result · 2024-08-26Clinical Trial Update: Effects of Itraconazole and Rifampin on the Blood Tazemetostat Levels [Phase 1]
Phase 1 trial assessing the pharmacokinetic interactions of itraconazole and rifampin with tazemetostat; results published for patients with…
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CLINICAL_TRIALS trial_result · 2024-08-21Clinical Trial Update: CD19-targeted CAR T Cells for Relapsed and Refractory (R/R) Large B-cell Lymphoma [Phase 2]
This document provides an update on a Phase 2 clinical trial of CD19-targeted CAR T cells for relapsed or refractory large B-cell lymphoma.
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CLINICAL_TRIALS trial_result · 2024-08-21Clinical Trial Update: ENABLE-1 (Engaging Toll-like Receptor Signalling for B-cell Lymphoma Chimeric Antigen Receptor Therapy) [Phase 1]
The ENABLE-1 Phase 1 trial investigates Toll-like receptor signaling to enhance B-cell lymphoma CAR-T therapy, with the study currently list…
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CLINICAL_TRIALS trial_result · 2024-08-20Clinical Trial Update: CLBR001 and SWI019 in Patients With Relapsed / Refractory B-cell Malignancies [Phase 1]
Phase 1 trial update for CLBR001 and SWI019 in relapsed/refractory B-cell malignancies has completed enrollment in a study targeting multipl…
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CLINICAL_TRIALS trial_result · 2024-08-13Clinical Trial Update: First-in-Human (FIH) Trial of GEN3009 in Subjects With Relapsed or Refractory B-Cell Non-Hodgkin Lymphomas [Phase 1, Phase 2]
First-in-human study of GEN3009 in relapsed or refractory B-cell non-Hodgkin lymphomas was terminated, with results posted thereafter.
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CLINICAL_TRIALS trial_result · 2024-08-12Clinical Trial Update: A Multicentre, Parallel Arm, Open-label Trial of Frontline R-CHOP/Pola-RCHP and Glofitamab in Younger, Higher Risk Patients With Diffuse Large B Cell Lymphoma (DLBCL) [Phase 1, Phase 2]
A multicentre, open-label Phase 1/2 trial is evaluating frontline regimens R-CHOP/Pola-RCHP and Glofitamab in younger patients with high-ris…
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: Study of TG-1801 Alone or in Combination With Ublituximab in Subjects With B-Cell Lymphoma or Chronic Lymphocytic Leukemia [Phase 1]
Phase 1 study assessing TG-1801 alone or with ublituximab in patients with CLL, SLL, and other B-cell lymphomas was terminated.
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CLINICAL_TRIALS trial_result · 2024-07-25Clinical Trial Update: Health-Related Quality of Life Outcomes in Patients With Aggressive B-Cell Lymphomas Treated With CAR-T Cell Therapy in Real Life
This clinical trial update discusses health-related quality of life outcomes in patients with aggressive B-cell lymphomas treated with CAR-T…
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CLINICAL_TRIALS trial_result · 2024-07-24Clinical Trial Update: An Open-label, Single-arm Study of JWCAR201 in the Treatment of Relapsed or Refractory Diffuse Large B-cell Lymphoma [Phase 1]
This document describes an open-label, single-arm Phase 1 trial evaluating the CAR-T therapy JWCAR201 in patients with relapsed or refractor…
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CLINICAL_TRIALS trial_result · 2024-07-24Clinical Trial Update: A Study of Imvotamab Monotherapy and in Combination in Subjects With Relapsed/Refractory Non-Hodgkin Lymphoma [Phase 1, Phase 2]
A Phase 1/Phase 2 study evaluating Imvotamab monotherapy and in combination for relapsed/refractory non-Hodgkin lymphoma has been terminated…