Developmental and Epileptic Encephalopathy

• CLINICAL_TRIALS research · 2026-04-15
  Clinical Trial Update: A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathies (DEE) [Phase 3]

  A Phase 3 clinical trial to evaluate LP352 for developmental and epileptic encephalopathy in children and adults is currently recruiting. Th…

• CLINICAL_TRIALS research · 2026-04-15
  Clinical Trial Update: SLC6A1-NDD Prospective Longitudinal Natural History Study

  This clinical trial update describes a prospective longitudinal natural history study of SLC6A1-related neurodevelopmental disorder and rela…

• CLINICAL_TRIALS research · 2026-02-17
  Clinical Trial Update: Genetic Developmental and Epileptic Encephalopathy Natural History Study for Clinical Trial Readiness

  This clinical trial update describes an ongoing natural history study of genetic developmental and epileptic encephalopathy, including MEF2C…

• CLINICAL_TRIALS research · 2026-02-09
  Clinical Trial Update: Developmental and Epileptic Encephalopathies Diagnosed Via Long-read Genome Sequencing

  A clinical trial evaluating long-read genome sequencing to diagnose developmental and epileptic encephalopathies in children; the study is n…

• CLINICAL_TRIALS research · 2026-01-22
  Clinical Trial Update: Phenylbutyrate for Monogenetic Developmental and Epileptic Encephalopathy [EARLY_Phase 1]

  Status update on a Phase 1 trial evaluating phenylbutyrate for monogenic developmental and epileptic encephalopathies, including STXBP1-rela…

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• CLINICAL_TRIALS research · 2026-01-05
  Clinical Trial Update: A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathy (DEE) [Phase 3]

  Phase 3 study LP352 for Developmental and Epileptic Encephalopathy is currently enrolling by invitation in children and adults.

• CLINICAL_TRIALS research · 2025-12-18
  Clinical Trial Update: A Clinical Trial for Participants With DEE to Assess Efficacy, Safety, Tolerability, and PK of Relutrigine [Phase 3]

  A Phase 3 trial is recruiting to evaluate the efficacy, safety, tolerability, and pharmacokinetics of Relutrigine for Developmental and Epil…

• CLINICAL_TRIALS research · 2025-06-29
  Clinical Trial Update: Developmental and Epileptic Encephalopathy of Genetic Etiology: Natural History Through Reuse of Clinical Data

  This clinical trial update describes a natural history study of Developmental and Epileptic Encephalopathy of genetic etiology that will reu…

• CLINICAL_TRIALS research · 2025-03-04
  Clinical Trial Update: Home Ultra-long Term EEG Monitoring for Rare Epilepsies and Developmental and Epileptic Encephalopathies [NA]

  Clinical trial update for a study evaluating home ultra-long term EEG monitoring for rare epilepsies and developmental and epileptic encepha…

• CLINICAL_TRIALS research · 2025-01-22
  Clinical Trial Update: Intermediate-Size Expanded Access Protocol (EAP) for LP352

  Update on Longboard Pharmaceuticals' expanded access protocol for LP352, indicating availability for patients with Dravet syndrome, Lennox-G…