Dementia with Lewy Bodies
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Prospective Observational Study of the Relationship Between Sociodemographic Factors, Blood-based Biomarkers and Psychiatric Symptoms in Neurodegenerative Diseases and Mental Disorders
A prospective observational study examining how sociodemographic factors, blood-based biomarkers, and psychiatric symptoms relate across sev…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Digital Health Technologies for Progressive Supranuclear Palsy and Dementia With Lewy Bodies
BioSensics is conducting a digital health technology trial for Progressive Supranuclear Palsy and Dementia with Lewy Bodies, with recruitmen…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Ultra-High Resolution PET in Aging, Neurodegeneration and Psychotic Disorders [NA]
Clinical trial update for a study of Ultra-High Resolution PET imaging in aging, neurodegeneration and psychotic disorders; recruitment is o…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: PERSEVERE: Peer Mentor Support and Caregiver Education in Lewy Body Dementia [NA]
A clinical trial update for PERSEVERE, a study on peer mentor support and caregiver education for Lewy body dementia, currently active but n…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Longitudinal Imaging Biomarkers of Disease Progression in DLB [Phase 4]
This document provides an update on an ongoing Phase 4 trial investigating longitudinal imaging biomarkers to monitor disease progression in…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: [18F]F-DOPA Imaging in Patients With Autonomic Failure [Phase 1]
Phase 1 imaging trial of [18F]F-DOPA in autonomic failure syndromes (including Parkinson's disease, multiple system atrophy, and dementia wi…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Terazosin for Dementia With Lewy Bodies [Phase 1, Phase 2]
The update reports a Phase 1/Phase 2 study of terazosin for dementia with Lewy bodies that is not yet recruiting.
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Elucidating the Role of Cholinergic Degeneration in Cognitive Fluctuations in Lewy Body Dementia [Phase 4]
Phase 4 clinical trial investigating the role of cholinergic degeneration in cognitive fluctuations in Lewy body dementias; currently recrui…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Targeting Neuroinflammation as a Contributing Pathology in Alzheimer's Disease Dementia and Related Dementias [Phase 2]
Phase 2 trial investigating neuroinflammation as a contributing pathology in Alzheimer's disease dementia and related dementias; enrollment …
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Retrospective Observational Study of Blood-based Biomarkers in the Diagnosis and Monitoring of Patients With a Neurodegenerative Disease or Mental Disorder
This clinical trial update describes a retrospective observational study evaluating blood-based biomarkers for diagnosing and monitoring sev…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Expanded Access Program for CT1812 (Zervimesine)
Expanded Access Program update for Cognition Therapeutics' CT1812 (Zervimesine) in dementia with Lewy bodies.
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: Exploration of GCase Activity to Identify a Subpopulation Eligible for a Therapeutic Trial in Dementia With Lewy Bodies
This clinical trial update outlines evaluating glucocerebrosidase (GCase) activity to identify a subpopulation of patients with dementia wit…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: Improving Prognostic Confidence in Neurodegenerative Diseases Causing Dementia Using Peripheral Biomarkers and Integrative Modeling
This study aims to improve prognostic confidence in neurodegenerative diseases causing dementia by using peripheral biomarkers and integrati…
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: [18F]ACI-15916 PET in α-synucleinopathies [EARLY_Phase 1]
AC Immune SA reports an early-phase 1 trial evaluating its PET radioligand [18F]ACI-15916 for imaging alpha-synuclein in Parkinson's disease…
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: Parkinson's Disease and Movement Disorders Clinical Database
ClinicalTrials.gov entry for the Parkinson's Disease and Movement Disorders Clinical Database is currently recruiting and includes Parkinson…
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: tDCS Effect on Psychotic Symptoms in Dementia With Lewy Bodies (DLB), and Impacts on Caregiver Burden [NA]
A clinical trial is recruiting to evaluate the effect of transcranial direct current stimulation (tDCS) on psychotic symptoms in dementia wi…
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CLINICAL_TRIALS research · 2025-09-29Clinical Trial Update: OCT-Angiography and Adaptive Optics in Patients With Memory Impairment [NA]
An ongoing clinical trial is evaluating OCT-Angiography and adaptive optics imaging in memory-impaired patients, including Alzheimer's disea…
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: Contribution of Pathological Alpha-synuclein as a Diagnostic Biomarker for Dementia With Lewy Bodies [NA]
This clinical trial update explores pathological alpha-synuclein as a diagnostic biomarker for dementia with Lewy bodies, with the study sta…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Non-invasive Neurostimulation as a Tool for Diagnostics and Management for Neurodegenerative Diseases [NA]
A Kuopio University Hospital clinical trial is recruiting to evaluate non-invasive neurostimulation as a tool for diagnosing and managing ne…
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: The Effect of Repetitive Transcranial Magnetic Stimulation on Cognitive Improvement in Dementia With Lewy Bodies [Phase 1, Phase 2]
A phase 1/2 clinical trial is investigating repetitive transcranial magnetic stimulation for cognitive improvement in dementia with Lewy bod…
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: Personalized Repetitive Transcranial Magnetic Stimulation (rTMS) in Cognitive Fluctuations of Dementia With Lewy Bodies (DLB): Proof of Concept [NA]
This clinical trial update describes a proof-of-concept study using personalized repetitive transcranial magnetic stimulation to address cog…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: Identification of Prodromal Neurodegeneration in Serotonergic-Induced REM Sleep Behavior Disorder [NA]
An update on a clinical trial studying prodromal neurodegeneration in serotonergic-induced REM sleep behavior disorder. The study is current…
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Telehealth in Lewy Body Dementia [NA]
A university-sponsored clinical trial is currently recruiting to assess telehealth approaches for Lewy body dementia and related Lewy body c…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: Natural History Study of Synucleinopathies
An update on an ongoing natural history study of synucleinopathies, currently recruiting participants, including Parkinson's disease and rel…
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CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: ENhancing Outcomes in Cognitive Impairment Through Use of Home Sleep ApNea Testing [NA]
A recruiting clinical trial sponsored by Sunnybrook Health Sciences Centre is evaluating home sleep apnea testing to improve outcomes in cog…