Dementia with Lewy Bodies
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CLINICAL_TRIALS trial_result · 2026-07-10Clinical Trial Results: Impact of Bosutinib on Safety, Tolerability, Biomarkers and Clinical Outcomes in Dementia With Lewy Bodies [Phase 2]
Phase 2 trial assessing bosutinib for safety, tolerability, biomarkers, and clinical outcomes in dementia with Lewy bodies.
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CLINICAL_TRIALS trial_result · 2026-06-08Clinical Trial Results: K0706 for Patients Diagnosed With Dementia With Lewy Bodies [Phase 2]
Phase 2 clinical trial results for K0706 in patients with Dementia with Lewy Bodies have been posted after termination.
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Prospective Observational Study of the Relationship Between Sociodemographic Factors, Blood-based Biomarkers and Psychiatric Symptoms in Neurodegenerative Diseases and Mental Disorders
A prospective observational study examining how sociodemographic factors, blood-based biomarkers, and psychiatric symptoms relate across sev…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Digital Health Technologies for Progressive Supranuclear Palsy and Dementia With Lewy Bodies
BioSensics is conducting a digital health technology trial for Progressive Supranuclear Palsy and Dementia with Lewy Bodies, with recruitmen…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: A Clinical Study of Neflamapimod in Patients With Dementia With Lewy Bodies [Phase 2]
A Phase 2 clinical study of Neflamapimod in patients with Dementia with Lewy Bodies has completed.
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CLINICAL_TRIALS trial_result · 2026-04-06Clinical Trial Update: RewinD-LB - Clinical Study of Neflamapimod in Patients With Dementia With Lewy Bodies [Phase 2]
Phase 2 study of neflamapimod in dementia with Lewy bodies has completed.
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: Impact of Nilotinib on Safety, Tolerability, Pharmacokinetics and Biomarkers in Dementia With Lewy Bodies [Phase 2]
Phase 2 trial evaluating safety, tolerability, pharmacokinetics, and biomarker changes with nilotinib in patients with Dementia with Lewy bo…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Ultra-High Resolution PET in Aging, Neurodegeneration and Psychotic Disorders [NA]
Clinical trial update for a study of Ultra-High Resolution PET imaging in aging, neurodegeneration and psychotic disorders; recruitment is o…
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Neurological Soft Signs in Neurodegenerative Dementias
A University of Milano Bicocca–sponsored study evaluating neurological soft signs in several neurodegenerative dementias has completed.
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CLINICAL_TRIALS trial_result · 2026-03-23Clinical Trial Update: Cognitive Stimulation Therapy for Dementia: A Two-Armed Pragmatic Trial [NA]
A two-armed pragmatic trial evaluating cognitive stimulation therapy for dementia has completed. Results have been posted.
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: PERSEVERE: Peer Mentor Support and Caregiver Education in Lewy Body Dementia [NA]
A clinical trial update for PERSEVERE, a study on peer mentor support and caregiver education for Lewy body dementia, currently active but n…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Longitudinal Imaging Biomarkers of Disease Progression in DLB [Phase 4]
This document provides an update on an ongoing Phase 4 trial investigating longitudinal imaging biomarkers to monitor disease progression in…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: [18F]F-DOPA Imaging in Patients With Autonomic Failure [Phase 1]
Phase 1 imaging trial of [18F]F-DOPA in autonomic failure syndromes (including Parkinson's disease, multiple system atrophy, and dementia wi…
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CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: Study to Evaluate the Safety, Tolerability and Efficacy of CT1812 in Subjects With Mild to Moderate Dementia With Lewy Bodies [Phase 2]
A Phase 2 study evaluating the safety, tolerability and efficacy of CT1812 in adults with mild to moderate dementia with Lewy bodies has com…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Terazosin for Dementia With Lewy Bodies [Phase 1, Phase 2]
The update reports a Phase 1/Phase 2 study of terazosin for dementia with Lewy bodies that is not yet recruiting.
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Elucidating the Role of Cholinergic Degeneration in Cognitive Fluctuations in Lewy Body Dementia [Phase 4]
Phase 4 clinical trial investigating the role of cholinergic degeneration in cognitive fluctuations in Lewy body dementias; currently recrui…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Targeting Neuroinflammation as a Contributing Pathology in Alzheimer's Disease Dementia and Related Dementias [Phase 2]
Phase 2 trial investigating neuroinflammation as a contributing pathology in Alzheimer's disease dementia and related dementias; enrollment …
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Retrospective Observational Study of Blood-based Biomarkers in the Diagnosis and Monitoring of Patients With a Neurodegenerative Disease or Mental Disorder
This clinical trial update describes a retrospective observational study evaluating blood-based biomarkers for diagnosing and monitoring sev…
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CLINICAL_TRIALS trial_result · 2026-01-13Clinical Trial Update: The PACE-DLB Study
The PACE-DLB clinical trial, sponsored by the University of Florida, focused on dementia with Lewy bodies. The study status shows as complet…
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CLINICAL_TRIALS trial_result · 2026-01-08Clinical Trial Update: In Vivo PET of Synaptic Density in Cognitive Disorders
Clinical trial 'In Vivo PET of Synaptic Density in Cognitive Disorders' has completed enrollment/status. The study investigates in vivo PET …
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CLINICAL_TRIALS trial_result · 2025-12-24Clinical Trial Update: PET Imaging Evaluation of [11C]SY08 [EARLY_Phase 1]
Early-phase clinical trial evaluating the PET radiotracer [11C]SY08 for imaging Parkinson's disease, Multiple System Atrophy, and Dementia w…
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CLINICAL_TRIALS trial_result · 2025-12-16Clinical Trial Update: Palliative Care for Persons With Late-stage Alzheimer's and Related Dementias and Their Caregivers [NA]
This clinical trial update reports the completion and results posting of a study evaluating palliative care for persons with late-stage Alzh…
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CLINICAL_TRIALS trial_result · 2025-12-08Clinical Trial Update: Relationship Between Alzheimer Disease and Diminution of the Three Macular Nervous Retinal Layers [NA]
A completed clinical trial study examining the relationship between Alzheimer's disease and diminution of three macular retinal layers measu…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Expanded Access Program for CT1812 (Zervimesine)
Expanded Access Program update for Cognition Therapeutics' CT1812 (Zervimesine) in dementia with Lewy bodies.
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: Exploration of GCase Activity to Identify a Subpopulation Eligible for a Therapeutic Trial in Dementia With Lewy Bodies
This clinical trial update outlines evaluating glucocerebrosidase (GCase) activity to identify a subpopulation of patients with dementia wit…