Cystic Fibrosis
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CLINICAL_TRIALS trial_result · 2009-01-13Clinical Trial Update: PTC124 for Cystic Fibrosis [Phase 2]
PTC124 (ataluren) for cystic fibrosis has completed a Phase 2 clinical trial sponsored by PTC Therapeutics.
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CLINICAL_TRIALS trial_result · 2009-01-09Clinical Trial Update: Phenylbutyrate/Genistein Duotherapy in Delta F508-Homozygous(for Cystic Fibrosis) [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the combination of phenylbutyrate and genistein in Delta F508 homozygous cystic fibrosis patients has …
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CLINICAL_TRIALS trial_result · 2009-01-07Clinical Trial Update: Airway Clearance Using High Frequency Chest Wall Oscillation [Phase 3]
Phase 3 trial update on airway clearance using high-frequency chest wall oscillation in cystic fibrosis; the study has completed.
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CLINICAL_TRIALS trial_result · 2008-12-01Clinical Trial Update: A Phase I Study of Inhaled Sodium Pyruvate for the Treatment of Cystic Fibrosis. [Phase 1]
A Phase I study evaluating inhaled sodium pyruvate for cystic fibrosis has been terminated. The trial investigated safety and tolerability i…
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CLINICAL_TRIALS trial_result · 2008-11-14Clinical Trial Update: Development of a Noninvasive Method of Evaluation of Pulmonary Inflammation in the Condensates of Exhaled Air
A clinical trial evaluating a noninvasive method to evaluate pulmonary inflammation from exhaled air condensates was terminated.
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CLINICAL_TRIALS trial_result · 2008-10-23Clinical Trial Update: Study of Alendronate to Prevent and Treat Osteoporosis in Cystic Fibrosis Patients [Phase 4]
A Phase 4 trial completed by McMaster University studied alendronate to prevent and treat osteoporosis in cystic fibrosis patients.
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FDA approval · 2008-10-16FDA Approved: TOBI — Supplemental Application (Viatris Specialty LLC)
The FDA approved a supplemental application for TOBI (tobramycin) submitted by Viatris Specialty LLC.
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CLINICAL_TRIALS trial_result · 2008-09-30Clinical Trial Update: Malabsorption Blood Test:Toward a Novel Approach to Quantify Steatorrhea [Phase 4]
This update describes a Phase 4 clinical trial evaluating a malabsorption blood test to quantify steatorrhea in patients with cystic fibrosi…
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CLINICAL_TRIALS trial_result · 2008-09-09Clinical Trial Update: Phase II Study of Growth Hormone in Children With Cystic Fibrosis [Phase 2]
The document reports that a Phase II study of growth hormone in children with cystic fibrosis has been completed.
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CLINICAL_TRIALS trial_result · 2008-08-29Clinical Trial Update: Mannitol Dose Response Study in Cystic Fibrosis [Phase 2]
Phase 2 dose-response trial of inhaled mannitol for cystic fibrosis has completed.
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CLINICAL_TRIALS trial_result · 2008-08-08Clinical Trial Update: Effects of 5-Methyltetrahydrofolate and Vitamin B12 Supplemetation on Red Cell Membrane in Children With Cystic Fibrosis [NA]
This entry reports a completed clinical trial evaluating the effects of 5-Methyltetrahydrofolate and vitamin B12 supplementation on red bloo…
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CLINICAL_TRIALS research · 2008-06-17Clinical Trial Update: Ocular Surface Changes in Patients With Cystic Fibrosis
This clinical trial update reports ocular surface changes observed in patients with cystic fibrosis.
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CLINICAL_TRIALS trial_result · 2008-06-09Clinical Trial Update: A Study to Evaluate Nutropin AQ for the Treatment of Growth Restriction in Children With Cystic Fibrosis [Phase 2]
Phase 2 clinical trial evaluating Nutropin AQ for growth restriction in children with cystic fibrosis has completed.
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CLINICAL_TRIALS trial_result · 2008-03-13Clinical Trial Update: Standard vs. Biofilm Susceptibility Testing in Cystic Fibrosis (CF) [NA]
A completed clinical trial evaluating standard versus biofilm susceptibility testing in cystic fibrosis patients.
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FDA approval · 2008-03-11FDA Approved: TOBRAMYCIN — Original Application (Mylan Institutional LLC)
The FDA approved an original application for a generic Tobramycin product (TOBRAMYCIN) from Mylan Institutional LLC.
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CLINICAL_TRIALS trial_result · 2008-01-30Clinical Trial Update: Hydroxychloroquine in Cystic Fibrosis [Phase 1]
Phase 1 trial evaluating hydroxychloroquine for cystic fibrosis, sponsored by Vanderbilt University, has completed.
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CLINICAL_TRIALS trial_result · 2008-01-28Clinical Trial Update: Safety and Efficacy of Recombinant Adeno-Associated Virus Containing the CFTR Gene in the Treatment of Cystic Fibrosis [Phase 2, Phase 3]
A Phase 2/3 trial evaluating a recombinant adeno-associated virus carrying the CFTR gene for cystic fibrosis was terminated after assessing …
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CLINICAL_TRIALS trial_result · 2007-12-25Clinical Trial Update: Safety Study of Orally Administered Curcuminoids in Adult Subjects With Cystic Fibrosis [Phase 1]
Phase 1 safety study evaluating orally administered curcuminoids in adults with cystic fibrosis has been completed.
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CLINICAL_TRIALS trial_result · 2007-12-25Clinical Trial Update: Assessment of Inflammatory Mediators (AIM) [NA]
The AIM clinical trial investigating inflammatory mediators in cystic fibrosis has completed.
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CLINICAL_TRIALS research · 2007-11-27Clinical Trial Update: NPD Measurement in Infants
This document provides an update on a clinical trial examining nasal potential difference measurements in infants with cystic fibrosis.
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CLINICAL_TRIALS trial_result · 2007-11-01Clinical Trial Update: Study of Interferon Gamma-1b by Injection for the Treatment of Patients With Cystic Fibrosis [Phase 1, Phase 2]
A Phase 1/2 trial of interferon gamma-1b injections for cystic fibrosis has completed.
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CLINICAL_TRIALS trial_result · 2007-11-01Clinical Trial Update: Interferon Gamma-1b by Inhalation for the Treatment of Patients With Cystic Fibrosis [Phase 1, Phase 2]
A Phase 1/2 trial evaluating inhaled interferon gamma-1b for cystic fibrosis has completed, sponsored by InterMune.
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CLINICAL_TRIALS trial_result · 2007-08-13Clinical Trial Update: Anti-Inflammatory Pulmonal Therapy of CF-Patients With Amitriptyline and Placebo [Phase 2]
Phase 2 trial evaluating amitriptyline as an anti-inflammatory therapy in cystic fibrosis patients (including those with Pseudomonas aerugin…
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CLINICAL_TRIALS research · 2007-07-26Clinical Trial Update: Multi Breath Nitrogen Washout (MBNW) as a Measure of Small Airway Function in Patients With Respiratory Disease
A clinical trial update evaluating Multi Breath Nitrogen Washout as a measure of small airway function in patients with respiratory diseases…
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CLINICAL_TRIALS trial_result · 2007-06-07Clinical Trial Update: One Year Glargine Treatment in CFRD Children and Adolescents [Phase 4]
This document provides a Phase 4 update on a one-year insulin glargine treatment in children and adolescents with cystic fibrosis-related di…