Cystic Fibrosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: ACT With CF Self-Help Toolkit [NA]
Thomas Jefferson University is recruiting a trial of an Acceptance and Commitment Therapy–based self-help toolkit for people with cystic fib…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Proof-of-concept Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of SION-719 When Added to Trikafta [Phase 2]
A Phase 2 proof-of-concept trial is evaluating the safety, tolerability, pharmacodynamics, and pharmacokinetics of SION-719 when added to Tr…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Characterisation of a Population of Adults Suffering From Cystic Fibrosis in a Belgian Reference Center
A clinical trial characterizes adults with cystic fibrosis at a Belgian reference center. The study also investigates quality of life and di…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Xenon-129 and Inert Fluorinated Gas Lung MRI: Study of Healthy Volunteers and Participants With Pulmonary Disease [Phase 2]
Phase 2 clinical trial update on Xenon-129 and inert fluorinated gas lung MRI in healthy volunteers and patients with pulmonary disease. Rec…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: COVID-19 ANtibody Responses in Cystic Fibrosis: CAR-CF
This clinical trial update reports the completion of a study evaluating antibody responses to COVID-19 in people with cystic fibrosis treate…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Assessment of CFTR-Modulator Treatment in Cystic Fibrosis Lung Disease Using Novel Structural and Functional MRI
The study investigates how CFTR-modulator therapy affects lung structure and function in cystic fibrosis using novel MRI techniques. It incl…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Modulate-CF: Cystic Fibrosis Transmembrane Regulator (CFTR) Biomarker Study to Evaluate the Rescue of Mutant CFTR in Patients With Cystic Fibrosis Treated With CFTR-modulators
A clinical trial update for Modulate-CF, a cystic fibrosis biomarker study assessing rescue of mutant CFTR in patients treated with CFTR mod…
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CLINICAL_TRIALS trial_result · 2026-02-23Clinical Trial Update: COVID-19 Antibody Responses in Cystic Fibrosis [NA]
A clinical trial update reports on COVID-19 antibody responses in individuals with cystic fibrosis; the study has completed.
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Microbial Biomarkers of EArly Pseudomonas Aeruginosa Colonization in CHildren With Cystic Fibrosis [NA]
A clinical trial investigating microbial biomarkers of early Pseudomonas aeruginosa colonization in children with cystic fibrosis. The study…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Population Pharmacokinetics of Elexacaftor-tezacaftor-ivacaftor in a Paediatric Population
Clinical trial update on the population pharmacokinetics of the CFTR modulator triple therapy elexacaftor-tezacaftor-ivacaftor in a paediatr…
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: The Sinonasal Cavity as a Reservoir for Upper Airway Bacterial Development
Completed clinical trial sponsored by the University of Minnesota examining whether the sinonasal cavity acts as a reservoir for upper airwa…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: A Cohort for Inflammatory Respiratory Diseases: From Phenotyping to Personalised Medicine
A clinical trial update describes a cohort study aimed at phenotyping inflammatory respiratory diseases to enable personalised medicine, cur…
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CLINICAL_TRIALS trial_result · 2026-02-18Clinical Trial Update: Clean Air for Rare MUcociliary Clearance dIsorders [NA]
This clinical trial update indicates that a study addressing rare mucociliary clearance disorders, including Primary Ciliary Dyskinesia and …
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EMA approval · 2026-02-17EMA Authorised: Bronchitol (mannitol) — Pharmaxis Europe Limited
The EMA authorised Bronchitol (mannitol) for cystic fibrosis, marking EU approval with Pharmaxis Europe Limited as the marketing authorizati…
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: STaph Aureus Resistance-Treat Early and Repeat (STAR-TER) [Phase 2]
Phase 2 trial STAR-TER evaluating early and repeat treatment for Staphylococcus aureus in cystic fibrosis; the study has completed.
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: 19F MRI in Healthy Children and Children With Mild Cystic Fibrosis Lung Disease
A clinical trial is evaluating fluorine-19 MRI imaging in healthy children and children with mild cystic fibrosis lung disease; the study is…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Novel Point-of-care Sweat Chloride Testing Device for Monitoring CFTR Function [NA]
A clinical trial from Emory University evaluating a novel point-of-care sweat chloride device to monitor CFTR function in cystic fibrosis; t…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Quantitation and Spatial Registration of Airways Dysfunction With Dynamic 19F MRI in Cystic Fibrosis
A clinical trial update notes an ongoing study using dynamic 19F MRI to quantify and spatially register airway dysfunction in cystic fibrosi…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: A Prospective Study of Advanced Diagnostics in People With an Unclear Diagnosis of Cystic Fibrosis
A prospective study evaluating advanced diagnostics for people with an unclear diagnosis of cystic fibrosis; the study is not yet recruiting…
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: CF Wellness Program [NA]
A Johns Hopkins University–sponsored CF Wellness Program trial is currently recruiting and investigates cystic fibrosis with sleep-related i…
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CLINICAL_TRIALS trial_result · 2026-02-13Clinical Trial Update: Comparison Between Ultra-low-dose Computed Tomography and Lung MRI in Cystic Fibrosis [NA]
This completed clinical trial compares ultra-low-dose computed tomography to lung MRI for imaging in patients with cystic fibrosis.
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: CF And Effects of Drugs Mixed Ex Vivo With Sputum for Mucolytic Treatment
The UCSF-sponsored clinical trial investigated the ex vivo mucolytic effects of drugs mixed with sputum from individuals with cystic fibrosi…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Studying the Presence of CFRD Complications With Thoughtful Recruitment (SPeCTRuM)
The SPeCTRuM trial, sponsored by the Jaeb Center for Health Research, is currently recruiting. It studies CFRD-related complications in cyst…
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CLINICAL_TRIALS trial_result · 2026-02-09Clinical Trial Update: Study to Evaluate the Safety & Tolerability of MRT5005 Administered by Nebulization in Adults With Cystic Fibrosis [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the safety and tolerability of MRT5005 administered by nebulization in adults with cystic fibrosis has…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Evaluation of Long-Term Safety and Efficacy of Vanzacaftor/Tezacaftor/Deutivacaftor in Cystic Fibrosis Participants 1 Year of Age and Older [Phase 3]
Phase 3 clinical trial evaluating the long-term safety and efficacy of the triple CFTR modulator combination Vanzacaftor/Tezacaftor/Deutivac…