Cystic Fibrosis
📧 Sign up to get email alerts when something new happens for Cystic Fibrosis.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2022-10-06Clinical Trial Update: IV Colistin for Pulmonary Exacerbations: Improving Safety and Efficacy [Phase 4]
Phase 4 trial update on intravenous colistin for pulmonary exacerbations in cystic fibrosis patients, focusing on safety and efficacy with r…
-
FDA approval · 2022-09-28FDA Approved: PERTZYE — Supplemental Application (Digestive Care, Inc.)
FDA approved a supplemental application for PERTZYE (pancrelipase) from Digestive Care, Inc., approving changes to the product's labeling. P…
-
CLINICAL_TRIALS trial_result · 2022-09-13Clinical Trial Update: OPTION 2: A Trial to Assess the Safety and Efficacy of MS1819 in Enteric Capsules in Patients With Cystic Fibrosis [Phase 2]
Phase 2 trial update for MS1819 in enteric capsules evaluating safety and efficacy in Exocrine Pancreatic Insufficiency and Cystic Fibrosis;…
-
CLINICAL_TRIALS trial_result · 2022-09-07Clinical Trial Update: Intravenous Iron in Adults With Cystic Fibrosis [Phase 4]
Phase 4 trial update on intravenous iron in adults with cystic fibrosis and iron deficiency has completed.
-
FDA approval · 2022-09-02FDA Approved: ORKAMBI — Supplemental Application (Vertex Pharmaceuticals Incorporated)
The FDA approved a supplemental application for ORKAMBI (lumacaftor and ivacaftor) from Vertex Pharmaceuticals Incorporated.
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
FDA approval · 2022-09-02FDA Approved: ORKAMBI — Supplemental Application (Vertex Pharmaceuticals Incorporated)
The FDA approved a supplemental application for ORKAMBI (lumacaftor/ivacaftor) from Vertex Pharmaceuticals.
-
CLINICAL_TRIALS trial_result · 2022-07-26Clinical Trial Update: A Study Evaluating Efficacy and Safety of Elexacaftor/Tezacaftor/Ivacaftor in Subjects 6 Through 11 Years of Age With Cystic Fibrosis and F/MF Genotypes [Phase 3]
Phase 3 trial evaluating the efficacy and safety of Elexacaftor/Tezacaftor/Ivacaftor in children aged 6-11 with Cystic Fibrosis has complete…
-
CLINICAL_TRIALS trial_result · 2022-07-14Clinical Trial Update: Study of VX-121 in Healthy Subjects and in Subjects With Cystic Fibrosis [Phase 1, Phase 2]
Phase 1/2 trial updates for VX-121 in healthy subjects and cystic fibrosis patients have completed with results posted.
-
CLINICAL_TRIALS withdrawal · 2022-06-30Clinical Trial Update: A Dose-finding Study of Inhaled OligoG vs Placebo in Patients With Cystic Fibrosis [Phase 2, Phase 3]
A dose-finding study of inhaled OligoG vs placebo in cystic fibrosis was withdrawn.
-
CLINICAL_TRIALS trial_result · 2022-06-10Clinical Trial Update: Special Investigation (All Cases) of LipaCreon in Patients With Pancreatic Exocrine Insufficiency Due to Cystic Fibrosis
Clinical trial update for LipaCreon in pancreatic exocrine insufficiency due to cystic fibrosis has completed; results posted.
-
CLINICAL_TRIALS trial_result · 2022-06-06Clinical Trial Update: OPTION: A Trial to Assess the Safety & Efficacy of MS1819 in Patients With Exocrine Pancreatic Insufficiency Due to Cystic Fibrosis [Phase 2]
Phase 2 trial update for MS1819 in exocrine pancreatic insufficiency due to cystic fibrosis; trial completed with results posted in 2022.
-
CLINICAL_TRIALS trial_result · 2022-05-16Clinical Trial Update: Study of Aztreonam for Inhalation in Children With Cystic Fibrosis and New Infection of the Airways by Pseudomonas Aeruginosa Bacteria [Phase 3]
Phase 3 trial of aztreonam for inhalation in children with cystic fibrosis and new Pseudomonas aeruginosa infection was terminated; results …
-
CLINICAL_TRIALS research · 2022-04-19Clinical Trial Update: MRI for Non-Invasive Imaging in Neonates and Children [NA]
Clinical trial update on MRI imaging in neonates and children; study completed with posted results.
-
CLINICAL_TRIALS trial_result · 2022-03-16Clinical Trial Update: RhDNase and Biodistribution of PMN Serine Proteases in Cystic Fibrosis Sputum [Phase 4]
Phase 4 trial update evaluating RhDNase and biodistribution of PMN serine proteases in cystic fibrosis sputum has completed.
-
CLINICAL_TRIALS trial_result · 2022-02-17Clinical Trial Update: Effect of Proton Pump Inhibitors on CF Pulmonary Exacerbations [Phase 2]
Phase 2 trial update on how proton pump inhibitors affect pulmonary exacerbations in cystic fibrosis.
-
CLINICAL_TRIALS trial_result · 2022-02-09Clinical Trial Update: Effect of Chronic Incretin-based Therapy in Cystic Fibrosis [NA]
A completed clinical trial evaluating chronic incretin-based therapy in cystic fibrosis with pancreatic insufficiency; results posted in 202…
-
CLINICAL_TRIALS trial_result · 2022-02-01Clinical Trial Update: Continuous Infusion Piperacillin-tazobactam for the Treatment of Cystic Fibrosis [Phase 4]
Phase 4 trial update on continuous infusion piperacillin-tazobactam for cystic fibrosis; study terminated with results posted.
-
CLINICAL_TRIALS trial_result · 2022-01-25Clinical Trial Update: A Phase 2 Study to Evaluate Efficacy and Safety of VX-561 in Subjects Aged 18 Years and Older With Cystic Fibrosis [Phase 2]
Phase 2 study evaluating VX-561 in adults with cystic fibrosis completed; results posted in 2022.
-
CLINICAL_TRIALS trial_result · 2022-01-25Clinical Trial Update: A Study Evaluating the Long Term Safety and Efficacy of VX-659 Combination Therapy [Phase 3]
Phase 3 trial of VX-659 combination therapy for cystic fibrosis was terminated; results posted previously in 2022.
-
CLINICAL_TRIALS trial_result · 2022-01-18Clinical Trial Update: A Study of VX-445 in Healthy Subjects and Subjects With Cystic Fibrosis [Phase 1, Phase 2]
Phase 1/2 clinical trial of VX-445 (elexacaftor) in healthy subjects and cystic fibrosis patients completed with posted results.
-
CLINICAL_TRIALS trial_result · 2022-01-14Clinical Trial Update: Antibiotic Treatment Of Staphylococcus Aureus In Stable People With CF [Phase 3]
Phase 3 clinical trial update on antibiotic treatment for Staphylococcus aureus in stable people with cystic fibrosis.
-
CLINICAL_TRIALS trial_result · 2021-12-08Clinical Trial Update: A Study to Explore the Impact of Lumacaftor/Ivacaftor on Disease Progression in Subjects Aged 2 Through 5 Years With Cystic Fibrosis, Homozygous for F508del [Phase 2]
Phase 2 study assessing the impact of Lumacaftor/Ivacaftor on disease progression in young children with cystic fibrosis homozygous for F508…
-
CLINICAL_TRIALS trial_result · 2021-11-26Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of Long-term Treatment With TEZ/IVA in CF Participants With an F508del CFTR Mutation [Phase 3]
A Phase 3 trial evaluating long-term safety and efficacy of TEZ/IVA in cystic fibrosis patients with the F508del CFTR mutation has completed…
-
CLINICAL_TRIALS trial_result · 2021-11-05Clinical Trial Update: AeroVanc in the Treatment of Methicillin-resistant Staphylococcus Aureus Infection in Patients With Cystic Fibrosis [Phase 3]
Phase 3 trial update for AeroVanc in MRSA-infected cystic fibrosis patients has completed with results posted.
-
CLINICAL_TRIALS trial_result · 2021-10-22Clinical Trial Update: Evaluation of VX 445/TEZ/IVA in Cystic Fibrosis Subjects 6 Through 11 Years of Age [Phase 3]
A Phase 3 trial update on VX-445/TEZ/IVA (elexacaftor/tezacaftor/ivacaftor) in children aged 6-11 with cystic fibrosis has completed with re…