Cystic Fibrosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Host and Bacterial Mechanisms During Cystic Fibrosis Pulmonary Exacerbations
Completed clinical trial update investigating host and bacterial mechanisms during pulmonary exacerbations in cystic fibrosis. The update do…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Effects of High-Frequency Chest Wall Oscillation Combined With Concurrent Training on Cough,in Cystic Fibrosis Patients [NA]
A clinical trial investigating whether high-frequency chest wall oscillation combined with concurrent training improves cough in people with…
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: Bacteriophages for Adults With Cystic Fibrosis and Chronic Achromobacter Lung Infection [Phase 1]
Phase 1 clinical trial evaluating bacteriophages for adults with cystic fibrosis and chronic Achromobacter xylosoxidans infection. The study…
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CLINICAL_TRIALS trial_result · 2026-04-06Clinical Trial Update: DNA Methylation and Lung Disease in Cystic Fibrosis [NA]
This completed clinical trial from University Hospital, Montpellier studied DNA methylation and lung disease in cystic fibrosis.
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: Evaluation of the Lung Clearance Index [NA]
A clinical trial update noting the completion of a study evaluating the Lung Clearance Index in cystic fibrosis patients.
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: Identification of Predictive Epigenetic Biomarkers of Lung Disease Severity in Cystic Fibrosis [NA]
A completed clinical trial identified epigenetic biomarkers that may predict the severity of lung disease in cystic fibrosis.
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: Effect of Vanzacaftor/Tezacaftor/Deutivacaftor (VNZ/TEZ/D-IVA) on the PK of Rosuvastatin in Healthy Participants [Phase 1]
A Phase 1 trial evaluated whether Vanzacaftor/Tezacaftor/Deutivacaftor (VNZ/TEZ/D-IVA) alters the pharmacokinetics of rosuvastatin in health…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Exercises' Effect on Muscle Strength, Aerobic Capacity and Respiratory Functions in Cystic Fibrosis [NA]
This clinical trial entry indicates a study examining the effects of exercise on muscle strength, aerobic capacity, and respiratory function…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Dose Escalation Study Evaluating the Safety and Pharmacokinetics of VX-272 in Healthy Participants [Phase 1]
An early-phase dose-escalation study from Vertex to evaluate the safety and pharmacokinetics of VX-272 in healthy participants, currently re…
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EMA approval · 2026-03-30EMA Authorised: Alyftrek (deutivacaftor;tezacaftor;vanzacaftor calcium dihydrate) — Vertex Pharmaceuticals (Ireland) Limited
EMA authorised Alyftrek, a triple combination cystic fibrosis medicine (deutivacaftor/tezacaftor/vanzacaftor calcium dihydrate) by Vertex Ph…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Evaluation of VX-121/Tezacaftor/Deutivacaftor in Cystic Fibrosis (CF) Participants 1 Through 11 Years of Age [Phase 3]
A Phase 3 clinical trial evaluating the VX-121/Tezacaftor/Deutivacaftor combination in children with cystic fibrosis aged 1 through 11 years…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Tele-Rehabilitation in Adults With Cystic Fibrosis [NA]
A clinical trial at King Saud University is evaluating tele-rehabilitation for adults with cystic fibrosis, including those with sarcopenia …
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FDA approval · 2026-03-27FDA Approved: TRIKAFTA — Supplemental Application (Vertex Pharmaceuticals Incorporated)
FDA approved a supplemental application for TRIKAFTA (elexacaftor/tezacaftor/ivacaftor) from Vertex Pharmaceuticals, resulting in updated la…
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FDA approval · 2026-03-27FDA Approved: ALYFTREK — Supplemental Application (Vertex Pharmaceuticals Incorporated)
The FDA approved a supplemental application for ALYFTREK (a triple combination of vanzacaftor, tezacaftor, and deutivacaftor) from Vertex Ph…
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FDA approval · 2026-03-27FDA Approved: TRIKAFTA — Supplemental Application (Vertex Pharmaceuticals Incorporated)
The FDA processed/approved a supplemental application for TRIKAFTA (elexacaftor/tezacaftor/ivacaftor) submitted by Vertex Pharmaceuticals In…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Ivacaftor in French Patients With Cystic Fibrosis and a G551D Mutation
This clinical trial update reports the completion of a study evaluating Ivacaftor in French patients with cystic fibrosis carrying the G551D…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Natural History of Noncirrhotic Portal Hypertension
This clinical trial update notes that a NIDDK-supported study is investigating the natural history of idiopathic noncirrhotic portal hyperte…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Physical Impairments in Children With Cystic Fibrosis
This clinical trial is studying physical impairments in children with cystic fibrosis and is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: A Phase 1/2 Study of VX-522 in Participants With Cystic Fibrosis (CF) [Phase 1, Phase 2]
A Phase 1/2 clinical trial of VX-522 in participants with cystic fibrosis is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Understanding Inflammation, InFection and Interventions in Severe Exacerbations of Cystic Fibrosis
This clinical trial aims to understand inflammation, infection and interventions in severe exacerbations of cystic fibrosis. It is currently…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Exercise in Child Health [NA]
A University of California, Irvine-sponsored clinical trial is recruiting to evaluate exercise in child health, including cystic fibrosis, s…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Colorectal Cancer Screening in Cystic Fibrosis
University of Washington is conducting a study on colorectal cancer screening in people with cystic fibrosis; the trial is currently active …
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Pulmonary Condensate: Non-invasive Evaluation of Pulmonary Involvement in Asthma and Cystic Fibrosis.
This clinical trial update describes a non-invasive method to evaluate pulmonary involvement in asthma and cystic fibrosis. The study is cur…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Prevalence and Impact of Depression and Anxiety in Cystic Fibrosis
A completed clinical trial evaluating the prevalence and impact of depression and anxiety among people with cystic fibrosis.
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Hormonal Responses to a Mixed Meal in People With Cystic Fibrosis [EARLY_Phase 1]
This EARLY Phase 1 study is evaluating hormonal responses to a mixed meal in people with cystic fibrosis. The trial, sponsored by the Univer…