Cystic Fibrosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: Modulation of Intestinal and Pulmonary Inflammation by Lactobacillus Diet Supplementation in Pediatric Cystic Fibrosis [NA]
Pediatric cystic fibrosis trial investigating whether Lactobacillus probiotic supplementation modulates intestinal and pulmonary inflammatio…
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CLINICAL_TRIALS trial_result · 2025-06-12Clinical Trial Update: Feasibility of Home-based Exercise Program for Adults With Cystic Fibrosis [Phase 2]
A Phase 2 clinical trial evaluated the feasibility of a home-based exercise program for adults with cystic fibrosis, with results posted.
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CLINICAL_TRIALS trial_result · 2025-06-11Clinical Trial Update: Home Airway Clearance in CF Patients [NA]
This update reports that a trial evaluating home airway clearance in cystic fibrosis patients has completed. No results are described in the…
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CLINICAL_TRIALS research · 2025-06-10Clinical Trial Update: Internet-delivered Cystic Fibrosis Mental Health Prevention, Wellness, Resource Program: How Does it Work? [NA]
This clinical trial update covers an internet-delivered mental health prevention program for children with cystic fibrosis and their sibling…
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CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: A Phase 1 Study to Evaluate the Relative Bioavailability of a VX-828 Tablet Formulation [Phase 1]
A Phase 1 study evaluating the relative bioavailability of a VX-828 tablet formulation in cystic fibrosis has completed.
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CLINICAL_TRIALS research · 2025-06-04Clinical Trial Update: The Development and Evaluation of iCF-PWR for Healthy Siblings of Individuals With Cystic Fibrosis [NA]
This clinical trial update reports completion of a study evaluating iCF-PWR, an internet-based intervention for healthy siblings of individu…
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CLINICAL_TRIALS research · 2025-05-31Clinical Trial Update: Analysis of Remote Monitoring/Virtual Clinic Data in Adult Patients With Cystic Fibrosis (Project Breathe)
A clinical trial update describing analysis of remote monitoring and virtual clinic data in adult cystic fibrosis patients under the Project…
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CLINICAL_TRIALS trial_result · 2025-05-29Clinical Trial Update: ANNE Sensor Monitoring in Cystic Fibrosis
A clinical trial evaluating ANNE sensor monitoring in cystic fibrosis has completed. The sponsor is Papworth Hospital NHS Foundation Trust.
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CLINICAL_TRIALS withdrawal · 2025-05-29Clinical Trial Update: Hyperpolarized Xenon Imaging in Patients With Cystic Fibrosis
Clinical trial investigating hyperpolarized xenon imaging in patients with cystic fibrosis has been withdrawn.
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CLINICAL_TRIALS research · 2025-05-29Clinical Trial Update: The Use of Breath Volatile Organic Compounds in Early Detection of Acute Pulmonary Exacerbations in Cystic Fibrosis
This completed clinical trial from Papworth Hospital NHS Foundation Trust investigates whether breath volatile organic compounds can detect …
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CLINICAL_TRIALS research · 2025-05-23Clinical Trial Update: Prospective Analysis of Urine LAM to Eliminate NTM Sputum Screening
A prospective study in cystic fibrosis examines using urine LAM testing to eliminate the need for sputum screening for nontuberculous mycoba…
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FDA approval · 2025-05-22FDA Approved: KALYDECO — Supplemental Application (Vertex Pharmaceuticals Incorporated)
The FDA approved a supplemental application for KALYDECO (ivacaftor) from Vertex Pharmaceuticals Incorporated.
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FDA approval · 2025-05-22FDA Approved: KALYDECO — Supplemental Application (Vertex Pharmaceuticals Incorporated)
The FDA approved Vertex's supplemental application for KALYDECO (ivacaftor), updating its labeling for use in cystic fibrosis.
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CLINICAL_TRIALS research · 2025-05-21Clinical Trial Update: Mycobacteriophage Treatment of Non-tuberculosis Mycobacteria
The update describes an ongoing clinical trial evaluating mycobacteriophage therapy for nontuberculous mycobacterial lung disease in cystic …
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CLINICAL_TRIALS trial_result · 2025-05-18Clinical Trial Update: Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA TC Combination Therapy in Participants With Cystic Fibrosis Who Are 6 Years of Age and Older [Phase 3]
Phase 3 long-term safety and efficacy data for the ELX/TEZ/IVA triple CF therapy in participants aged 6 and older. Results were posted in Ma…
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: Global Utilization And Registry Database for Improved preservAtion of doNor LUNGs
An ongoing clinical trial by Paragonix Technologies aims to create a global registry to improve donor lung preservation. Enrollment is by in…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Oral Health Status of Cystic Fibrosis Patients. An Online Survey in Collaboration With the Vaincre la Mucoviscidose Patient Association.
An online survey study to assess oral health in cystic fibrosis patients; sponsored by Assistance Publique - Hôpitaux de Paris in collaborat…
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CLINICAL_TRIALS trial_result · 2025-05-09Clinical Trial Update: PEP and O-PEP Device for Nebulization in Cystic Fibrosis [NA]
Clinical trial update on the PEP and O-PEP nebulization devices for cystic fibrosis; the study is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2025-05-08Clinical Trial Update: Effect of One Year Elexacaftor-tezacaftor-ivacaftor Treatment
A clinical trial update reports the completion of a one-year treatment with elexacaftor/tezacaftor/ivacaftor in cystic fibrosis.
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CLINICAL_TRIALS research · 2025-05-08Clinical Trial Update: A Prospective, Single-center, Open-label Clinical Study to Evaluate the Safety and Efficacy of Inhaled BMD003(CFTR mRNA) in Chinese Adult Patients With Cystic Fibrosis [EARLY_Phase 1]
A prospective, single-center, open-label Phase 1 trial evaluating inhaled BMD003 (CFTR mRNA) in adult Chinese patients with cystic fibrosis;…
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CLINICAL_TRIALS research · 2025-05-08Clinical Trial Update: Effectiveness of Gamified Mobile Health Apps for Airway Clearance Therapy in Children and Adolescents With Cystic Fibrosis [NA]
A clinical trial is evaluating whether gamified mobile health apps can improve airway clearance therapy in children and adolescents with cys…
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Targeting Inflammation With Losartan to Improve Response to Modulator Therapy in Cystic Fibrosis. [Phase 2]
A Phase 2 clinical trial sponsored by the University of Kansas Medical Center is evaluating whether adding losartan to modulator therapy can…
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CLINICAL_TRIALS research · 2025-04-27Clinical Trial Update: GLP-1 Agonist Therapy in Cystic Fibrosis-Related Glucose Intolerance [Phase 2]
Phase 2 trial evaluating a GLP-1 receptor agonist for glucose intolerance in cystic fibrosis is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-04-16Clinical Trial Update: Novel Therapeutic Approaches for Treatment of CF Patients With W1282X Premature Termination Codon Mutations [Phase 4]
A Phase 4 trial evaluating novel therapies for cystic fibrosis patients with the W1282X premature termination codon has been terminated, wit…
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CLINICAL_TRIALS research · 2025-04-15Clinical Trial Update: Markers of Osteoporosis in Cystic Fibrosis [Phase 4]
Phase 4 study examining markers of osteoporosis in patients with cystic fibrosis; currently recruiting.