Cystic Fibrosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-08-07Clinical Trial Update: MN4000 for Treatment of CF and MND Patients in the Home Setting [NA]
Results for a completed clinical trial (NCT03797677) evaluating MN4000 for home-based treatment of cystic fibrosis and motor neuron disease …
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CLINICAL_TRIALS trial_result · 2024-08-01Clinical Trial Update: Evaluation of Efficacy and Safety of Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) in Cystic Fibrosis Subjects Without an F508del Mutation [Phase 3]
A Phase 3 trial evaluating the efficacy and safety of the triple-combination CFTR modulator elexacaftor/tezacaftor/ivacaftor in cystic fibro…
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CLINICAL_TRIALS trial_result · 2024-07-23Clinical Trial Update: Study to Evaluate Symptoms of Exocrine Pancreatic Insufficiency in Adult Participants With Cystic Fibrosis or Chronic Pancreatitis Treated With Creon [Phase 4]
Phase 4 study evaluating symptoms of exocrine pancreatic insufficiency in adults with cystic fibrosis or chronic pancreatitis treated with C…
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CLINICAL_TRIALS trial_result · 2024-07-22Clinical Trial Update: A Comprehensive Approach To Relief Of Digestive Symptoms In Cystic Fibrosis: CARDS-CF
A clinical trial called CARDS-CF evaluated a comprehensive approach to relieving digestive symptoms in cystic fibrosis. The study status is …
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CLINICAL_TRIALS trial_result · 2024-07-16Clinical Trial Update: Study to Evaluate Adverse Events and Change in Disease Activity With Oral Capsules of Galicaftor/Navocaftor/ABBV-119 or Galicaftor/Navocaftor/ABBV-576 Combination Therapies in Adult Participants With Cystic Fibrosis [Phase 2]
Phase 2 trial evaluating adverse events and changes in disease activity in adults with cystic fibrosis for two fixed-dose combinations of ga…
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: CFTR Modulators and Gastrointestinal Complications
A completed clinical trial evaluating CFTR modulator therapies and their gastrointestinal complications in cystic fibrosis patients.
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: The Effect of Breathing Exercise With Pinwheel on the Quality of Life in Children With Cystic Fibrosis Disease [NA]
A completed clinical trial investigated whether pinwheel-assisted breathing exercises can improve quality of life in children with cystic fi…
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CLINICAL_TRIALS trial_result · 2024-07-01Clinical Trial Update: Prednisone in Cystic Fibrosis Pulmonary Exacerbations [Phase 3]
Phase 3 trial update on prednisone for pulmonary exacerbations in cystic fibrosis; the study status is completed.
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CLINICAL_TRIALS trial_result · 2024-06-26Clinical Trial Update: Physical Activity, Exercise Capacity and Coronavirus Phobia of Adult Cystic Fibrosis Patients During COVID-19 Pandemic
This trial update reports on physical activity, exercise capacity, and coronavirus-related anxiety in adult cystic fibrosis patients during …
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CLINICAL_TRIALS trial_result · 2024-06-24Clinical Trial Update: Inhaled Sodium Nitrite as an Antimicrobial for Cystic Fibrosis [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating inhaled sodium nitrite as an antimicrobial for cystic fibrosis was terminated; results were posted in …
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CLINICAL_TRIALS trial_result · 2024-06-17Clinical Trial Update: Study to Assess the Safety and PK of Oral and IV Xenleta in Adults With Cystic Fibrosis [Phase 1]
A Phase 1 study assessed the safety and pharmacokinetics of oral and intravenous lefamulin (Xenleta) in adults with cystic fibrosis; results…
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CLINICAL_TRIALS trial_result · 2024-06-13Clinical Trial Update: A Study of VX-121 Combination Therapy in Participants With Cystic Fibrosis (CF) Who Are Homozygous for F508del, Heterozygous for F508del and a Gating (F/G) or Residual Function (F/RF) Mutation, or Have At Least 1 Other Triple Combination Responsive (TCR) CFTR Mutation and No F508del Mutation [Phase 3]
Phase 3 study evaluating VX-121 combination therapy in cystic fibrosis patients with multiple CFTR mutations has completed, with results pos…
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CLINICAL_TRIALS trial_result · 2024-06-10Clinical Trial Update: A Phase 3 Study of VX-121 Combination Therapy in Participants With Cystic Fibrosis (CF) Heterozygous for F508del and a Minimal Function Mutation (F/MF) [Phase 3]
A Phase 3 study evaluating VX-121 combination therapy in cystic fibrosis patients who are heterozygous for F508del and a minimal function mu…
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CLINICAL_TRIALS trial_result · 2024-06-03Clinical Trial Update: A Study to Evaluate the Relative Bioavailability and Food Effect of a VX-118 Tablet Formulation [Phase 1]
Phase 1 study evaluating the relative bioavailability and food effect of VX-118 tablet formulation has been completed in cystic fibrosis.
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CLINICAL_TRIALS trial_result · 2024-05-30Clinical Trial Update: RATNO, Reducing Antibiotic Tolerance Using Nitric Oxide in CF - a Phase 2 Pilot Study [Phase 2]
An update on a Phase 2 pilot trial (RATNO) investigating nitric oxide to reduce antibiotic tolerance in cystic fibrosis.
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CLINICAL_TRIALS trial_result · 2024-05-23Clinical Trial Update: Gut Imaging for Function & Transit in CF - GIFT-CF 3
A completed clinical trial evaluating gut imaging for function and transit in cystic fibrosis (GIFT-CF 3).
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CLINICAL_TRIALS trial_result · 2024-05-21Clinical Trial Update: Trial of Aeroquin Versus Tobramycin Inhalation Solution (TIS) in Cystic Fibrosis (CF) Patients [Phase 3]
A Phase 3 trial comparing Aeroquin to Tobramycin Inhalation Solution in cystic fibrosis patients has completed, with results posted in May 2…
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: A Study of Vanzacaftor/Tezacaftor/Deutivacaftor (VNZ/TEZ/D-IVA) in Healthy Adult Panelists [Phase 1]
Phase 1 trial in healthy adult panelists evaluating the safety of the VNZ/TEZ/D-IVA fixed-dose combination has completed.
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CLINICAL_TRIALS trial_result · 2024-05-10Clinical Trial Update: Study of a Nebulised Nitric Oxide Generating Solution in Patients With Mycobacterium Abscessus [Phase 2]
A Phase 2 trial evaluating a nebulised nitric oxide generating solution in cystic fibrosis patients with Mycobacterium abscessus has been te…
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: A Study Evaluating the Long-term Safety and Efficacy of VX-445 Combination Therapy [Phase 3]
Phase 3 trial update reporting long-term safety and efficacy results for VX-445 combination therapy in cystic fibrosis; results have been po…
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: A Study Evaluating the Long-term Safety and Efficacy of Elexacaftor/Tezacaftor/Ivacaftor in Cystic Fibrosis (CF) Particpants 6 Years and Older and F/MF Genotypes [Phase 3]
This Phase 3 long-term safety and efficacy study of the elexacaftor/tezacaftor/ivacaftor combination in cystic fibrosis patients aged 6 year…
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: Effects of SIMEOX on Airway Clearance in Cystic Fibrosis [NA]
A completed clinical trial evaluating the effects of SIMEOX on airway clearance in patients with cystic fibrosis.
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CLINICAL_TRIALS trial_result · 2024-05-02Clinical Trial Update: HERO-2: Home-Reported Outcomes With CFTR Modulator Therapy
The HERO-2 trial update reports home-reported outcomes from participants receiving CFTR modulator therapy for cystic fibrosis, and the study…
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CLINICAL_TRIALS trial_result · 2024-04-30Clinical Trial Update: Proton Pump Inhibitors (PPI) and Fat Absorption in Cystic Fibrosis (CF) and Exocrine Pancreatic Insufficiency (EPI) [Phase 2]
Phase 2 trial evaluating the effect of proton pump inhibitors on fat absorption in cystic fibrosis with pancreatic exocrine insufficiency. T…
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CLINICAL_TRIALS trial_result · 2024-04-30Clinical Trial Update: MP-376 (Aeroquin™, Levofloxacin for Inhalation) in Patients With Cystic Fibrosis [Phase 3]
Phase 3 trial results for MP-376 (Aeroquin), an inhaled levofloxacin, in patients with cystic fibrosis have been posted.