Cystic Fibrosis
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: Determination of the Predictive Factors in the Reversibility or the Aggravation in the Disorders of the Glucose Metabolism in Cystic Fibrosis Patients [NA]
A completed clinical trial assessing predictive factors for reversibility or progression of glucose metabolism disorders in cystic fibrosis …
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CLINICAL_TRIALS trial_result · 2025-09-03Clinical Trial Update: Safety, Tolerability, and Pharmacokinetics of Multiple Dose Combinations of SION-451 and Complementary Modulators SION-2222 and SION-109 in Healthy Participants. [Phase 1]
Phase 1 clinical trial update evaluating safety, tolerability, and pharmacokinetics of multiple-dose combinations of SION-451 with SION-2222…
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CLINICAL_TRIALS trial_result · 2025-08-15Clinical Trial Update: Project 2 Airway Potential Hydrogen (pH) in Asthma [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial evaluating airway pH in patients with cystic fibrosis and asthma, sponsored by Case Western Reserve Uni…
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CLINICAL_TRIALS trial_result · 2025-08-12Clinical Trial Update: Baby Detect : Genomic Newborn Screening
Clinical trial update on the Baby Detect genomic newborn screening program, reporting completion of a study assessing screening for multiple…
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CLINICAL_TRIALS trial_result · 2025-08-11Clinical Trial Update: The Alfred Step Test Exercise Protocol (A-STEP), for Adults With Cystic Fibrosis. [NA]
The Alfred Step Test Exercise Protocol (A-STEP) trial for adults with cystic fibrosis has completed.
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CLINICAL_TRIALS trial_result · 2025-08-05Clinical Trial Update: A Study to Investigate the Safety and Tolerability of Single and Multiple Ascending Doses of KIT2014 in Healthy Subjects [Phase 1]
Phase 1 trial update reporting completion of a single- and multiple-ascending-dose study of KIT2014 in healthy subjects. The study lists Cys…
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CLINICAL_TRIALS trial_result · 2025-07-28Clinical Trial Update: Peer i-Coaching for Activated Self-Management Optimization in Adolescents and Young Adults With Chronic Conditions [NA]
Completed clinical trial results have been posted for the Peer i-Coaching program, evaluating activated self-management optimization in adol…
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CLINICAL_TRIALS trial_result · 2025-07-28Clinical Trial Update: Effectiveness of Respiratory Physiotherapy on Frequency of Exacerbations, Lung Function and Quality of Life After 6 Months in Children With Cystic Fibrosis [NA]
A completed clinical trial evaluating the effectiveness of respiratory physiotherapy on exacerbations, lung function, and quality of life ov…
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: Nebulized Bacteriophage Therapy in Cystic Fibrosis Patients With Chronic Pseudomonas Aeruginosa Pulmonary Infection [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating nebulized bacteriophage therapy for chronic Pseudomonas aeruginosa lung infection in cystic fibrosis p…
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: TAAI Erasmus Research Initiative to Fight CF: Monitoring Inflammation in CF Lung Disease Into a New Era
A completed clinical trial update from Erasmus Medical Center focusing on monitoring inflammation in cystic fibrosis lung disease as part of…
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: Non-pulmonary Contributors of Exercise Intolerance in Patients With Cystic Fibrosis [EARLY_Phase 1]
An early Phase 1 clinical trial assessing non-pulmonary contributors to exercise intolerance in cystic fibrosis has completed. The study was…
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CLINICAL_TRIALS trial_result · 2025-06-12Clinical Trial Update: Feasibility of Home-based Exercise Program for Adults With Cystic Fibrosis [Phase 2]
A Phase 2 clinical trial evaluated the feasibility of a home-based exercise program for adults with cystic fibrosis, with results posted.
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CLINICAL_TRIALS trial_result · 2025-06-11Clinical Trial Update: Home Airway Clearance in CF Patients [NA]
This update reports that a trial evaluating home airway clearance in cystic fibrosis patients has completed. No results are described in the…
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CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: A Phase 1 Study to Evaluate the Relative Bioavailability of a VX-828 Tablet Formulation [Phase 1]
A Phase 1 study evaluating the relative bioavailability of a VX-828 tablet formulation in cystic fibrosis has completed.
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CLINICAL_TRIALS trial_result · 2025-05-29Clinical Trial Update: ANNE Sensor Monitoring in Cystic Fibrosis
A clinical trial evaluating ANNE sensor monitoring in cystic fibrosis has completed. The sponsor is Papworth Hospital NHS Foundation Trust.
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CLINICAL_TRIALS trial_result · 2025-05-18Clinical Trial Update: Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA TC Combination Therapy in Participants With Cystic Fibrosis Who Are 6 Years of Age and Older [Phase 3]
Phase 3 long-term safety and efficacy data for the ELX/TEZ/IVA triple CF therapy in participants aged 6 and older. Results were posted in Ma…
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CLINICAL_TRIALS trial_result · 2025-05-09Clinical Trial Update: PEP and O-PEP Device for Nebulization in Cystic Fibrosis [NA]
Clinical trial update on the PEP and O-PEP nebulization devices for cystic fibrosis; the study is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2025-05-08Clinical Trial Update: Effect of One Year Elexacaftor-tezacaftor-ivacaftor Treatment
A clinical trial update reports the completion of a one-year treatment with elexacaftor/tezacaftor/ivacaftor in cystic fibrosis.
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CLINICAL_TRIALS trial_result · 2025-04-16Clinical Trial Update: Novel Therapeutic Approaches for Treatment of CF Patients With W1282X Premature Termination Codon Mutations [Phase 4]
A Phase 4 trial evaluating novel therapies for cystic fibrosis patients with the W1282X premature termination codon has been terminated, wit…
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CLINICAL_TRIALS trial_result · 2025-04-11Clinical Trial Update: Prediction by Ultrasound of the Risk of Hepatic Cirrhosis in Cystic Fibrosis
A completed study assessed whether ultrasound can predict the risk of hepatic cirrhosis in cystic fibrosis patients with pancreatic insuffic…
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CLINICAL_TRIALS trial_result · 2025-04-10Clinical Trial Update: Cystic Fibrosis Microbiome-determined Antibiotic Therapy Trial in Exacerbations: Results Stratified [NA]
A completed clinical trial in cystic fibrosis evaluated microbiome-guided antibiotic therapy for exacerbations, with results presented in st…
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CLINICAL_TRIALS trial_result · 2025-04-10Clinical Trial Update: Intrapulmonary Percussive Ventilation for Sputum Induction in Adults With Cystic Fibrosis [NA]
A clinical trial evaluating intrapulmonary percussive ventilation for sputum induction in adults with cystic fibrosis has completed. The upd…
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CLINICAL_TRIALS trial_result · 2025-04-08Clinical Trial Update: Efficacy of Intensive Cholecalciferol Monitoring and Supplementation on Serum vitD Levels in Pediatric Patients With CF [Phase 4]
This Phase 4 clinical trial update assesses whether intensive monitoring of cholecalciferol (vitamin D3) and supplementation improves serum …
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CLINICAL_TRIALS trial_result · 2025-04-04Clinical Trial Update: Cell Content of Sputum Induced by Hypertonic Saline in Adolescents With Cystic Fibrosis [NA]
Update on a terminated clinical trial assessing sputum cell content after inhaled hypertonic saline in adolescents with cystic fibrosis.
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CLINICAL_TRIALS trial_result · 2025-03-24Clinical Trial Update: Effects of Telerehabilitation-based Exercises in Cystic Fibrosis [NA]
A completed clinical trial evaluating telerehabilitation-based exercise interventions for individuals with cystic fibrosis, focusing on exer…