Cystic Fibrosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-10-29Clinical Trial Update: Bronchial Inflammation of Small Airways in Patients With Cystic Fibrosis
This trial update notes the completion of a study evaluating bronchial inflammation of the small airways in patients with cystic fibrosis.
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CLINICAL_TRIALS trial_result · 2014-10-24Clinical Trial Update: Liprotamase Efficacy Trial in Patients With Cystic Fibrosis-Related Exocrine Pancreatic Insufficiency [Phase 3]
A Phase 3 trial of Liprotamase in cystic fibrosis-related exocrine pancreatic insufficiency has completed.
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CLINICAL_TRIALS trial_result · 2014-10-24Clinical Trial Update: Open-Label Phase III Long-Term Safety Trial of Liprotamase [Phase 3]
The open-label Phase III long-term safety trial of Liprotamase has completed.
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CLINICAL_TRIALS trial_result · 2014-10-23Clinical Trial Update: Effect of Glycine in Cystic Fibrosis [Phase 2]
Phase 2 trial evaluating glycine for cystic fibrosis; the study was terminated, with results posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-10-21Clinical Trial Update: Safety, Tolerability and Pharmacokinetics of BIIL 284 BS in Adult and Pediatric Cystic Fibrosis (CF) Patients [Phase 1]
A Phase 1 study evaluating BIIL 284 BS in adults and children with cystic fibrosis completed, focusing on safety, tolerability, and pharmaco…
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CLINICAL_TRIALS trial_result · 2014-10-17Clinical Trial Update: Oral TheraCLEC™ - Total in Cystic Fibrosis Subjects With Exocrine Pancreatic Insufficiency [Phase 2]
Oral TheraCLEC is being studied in cystic fibrosis patients with exocrine pancreatic insufficiency in a Phase 2 trial. The study status is l…
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CLINICAL_TRIALS trial_result · 2014-10-16Clinical Trial Update: Safety, Tolerability and Pharmacokinetics of Increasing Doses of BIIL 284 BS in Adult and Pediatric Cystic Fibrosis (CF) Patients [Phase 1]
A Phase 1 trial evaluated safety, tolerability, and pharmacokinetics of escalating doses of BIIL 284 BS in adult and pediatric cystic fibros…
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CLINICAL_TRIALS trial_result · 2014-10-06Clinical Trial Update: Does a Daily Iron Tablet Improve Anemia in Cystic Fibrosis [NA]
A completed clinical trial assessed whether daily iron supplementation improves anemia in individuals with cystic fibrosis, with results pos…
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CLINICAL_TRIALS trial_result · 2014-09-05Clinical Trial Update: Changes in Adherence After Playing "My Life With CF" Game [NA]
A completed clinical trial assessed changes in treatment adherence after participants played the 'My Life With CF' game.
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CLINICAL_TRIALS trial_result · 2014-08-22Clinical Trial Update: Imaging Lung Function Using Oxygen Enhanced MRI [Phase 1]
Phase 1 trial update evaluating oxygen-enhanced MRI to image lung function; the study status is completed and encompasses COPD, asthma, and …
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CLINICAL_TRIALS trial_result · 2014-08-21Clinical Trial Update: Deposition of Inhaled Prolastin in Cystic Fibrosis Patients [Phase 2]
Phase 2 results were posted for a study evaluating deposition of inhaled Prolastin in cystic fibrosis patients.
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CLINICAL_TRIALS trial_result · 2014-08-21Clinical Trial Update: Supplementation of Oral Reduced Glutathione in Pediatric Cystic Fibrosis Patients [NA]
A completed pediatric cystic fibrosis trial evaluating oral reduced glutathione supplementation; results were posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-08-13Clinical Trial Update: Volatile Organic Compounds in Cystic Fibrosis
A completed clinical trial evaluating volatile organic compounds in cystic fibrosis patients.
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CLINICAL_TRIALS trial_result · 2014-08-12Clinical Trial Update: Phase 1b Safety, Tolerability, and PK Study to Assess GS-5737 in Subjects With CF [Phase 1]
Phase 1b safety, tolerability, and pharmacokinetic study of GS-5737 in subjects with cystic fibrosis has completed.
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CLINICAL_TRIALS trial_result · 2014-08-11Clinical Trial Update: Phase 1, QT/QTC Interval Study in Healthy Subjects [Phase 1]
Vertex completed a Phase 1 QT/QTc interval safety study in healthy volunteers for a cystic fibrosis drug candidate (Lumacaftor, VX-809).
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CLINICAL_TRIALS trial_result · 2014-07-31Clinical Trial Update: Study of the Effect of VX-770 on Hyperpolarized Helium-3 Magnetic Resonance Imaging in Subjects With Cystic Fibrosis and the G551D Mutation [Phase 2]
Phase 2 study assessing the effect of ivacaftor (VX-770) on hyperpolarized Helium-3 MRI markers in cystic fibrosis patients with the G551D C…
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CLINICAL_TRIALS trial_result · 2014-07-03Clinical Trial Update: Non Invasive Ventilation as Airway Clearance in Patients With Cystic Fibrosis [NA]
A completed clinical trial evaluated non-invasive ventilation as a method for airway clearance in cystic fibrosis patients. Results were pos…
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CLINICAL_TRIALS trial_result · 2014-07-01Clinical Trial Update: Aztreonam Lysine for Pseudomonas Infection Eradication Study [Phase 2]
Phase 2 trial update for aztreonam lysine aimed at eradicating Pseudomonas infection in cystic fibrosis; the completed study posted results …
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CLINICAL_TRIALS trial_result · 2014-06-30Clinical Trial Update: Effect of Hypertonic Saline on Mucus Clearance in Children Ages 5-12 With Cystic Fibrosis [NA]
A completed clinical trial evaluated the effect of hypertonic saline on mucus clearance in children aged 5-12 with cystic fibrosis; results …
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CLINICAL_TRIALS trial_result · 2014-06-25Clinical Trial Update: Utilizing Exhaled Breathe Condensate Collection to Study Ion Regulation in Cystic Fibrosis [NA]
A completed clinical trial investigating exhaled breath condensate collection to study ion regulation in cystic fibrosis and healthy control…
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CLINICAL_TRIALS trial_result · 2014-06-24Clinical Trial Update: Safety, Tolerability and Pharmacokinetics of Tiotropium in Cystic Fibrosis Patients [Phase 1]
This Phase 1 study evaluated safety, tolerability, and pharmacokinetics of tiotropium in cystic fibrosis patients. The update summarizes the…
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CLINICAL_TRIALS trial_result · 2014-06-20Clinical Trial Update: A Study Comparing the Efficacy and Tolerability of Tobrineb®/Actitob®/Bramitob® Versus TOBI® [Phase 3]
Phase 3 trial update comparing Tobrineb, Actitob, and Bramitob with TOBI in cystic fibrosis; results were posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-05-02Clinical Trial Update: Safety and Efficacy of Sildenafil in Cystic Fibrosis (CF) Lung Disease [Phase 1, Phase 2]
Phase 1/2 trial assessing safety and efficacy of sildenafil in cystic fibrosis lung disease has completed with results posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-05-01Clinical Trial Update: Safety of AZLI in Children With Cystic Fibrosis (CF) and Chronic Pseudomonas Aeruginosa in the Lower Airways [Phase 3]
Phase 3 safety results for AZLI in children with cystic fibrosis and chronic Pseudomonas aeruginosa infection have been posted. The trial is…
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CLINICAL_TRIALS trial_result · 2014-05-01Clinical Trial Update: A Study of the Comparable Efficacy and Safety of Pulmozyme (Dornase Alfa) Delivered by the eRapid Nebulizer System in Patients With Cystic Fibrosis [Phase 4]
Phase 4 trial evaluating whether Pulmozyme delivered by the eRapid Nebulizer System has comparable efficacy and safety to standard delivery …