Cystic Fibrosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-06-08Clinical Trial Update: Effects of an Antioxidant-Enriched Multivitamin Supplement on Inflammation and Oxidative Stress in Cystic Fibrosis [Phase 2]
Phase 2 trial evaluated an antioxidant-enriched multivitamin for reducing inflammation and oxidative stress in cystic fibrosis; results have…
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CLINICAL_TRIALS trial_result · 2017-06-01Clinical Trial Update: Phase I Randomized Study of Adeno-Associated Virus-CFTR Vector in Patients With Cystic Fibrosis [Phase 1]
Phase I randomized trial evaluating an adeno-associated virus-CFTR vector in cystic fibrosis patients; the study has completed.
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CLINICAL_TRIALS trial_result · 2017-05-16Clinical Trial Update: A Study to Determine the Variability of a 6-Minute Walk Test in Cystic Fibrosis Subjects With Advanced Lung Disease
A completed Genentech-sponsored study assessing the variability of the 6-minute walk test in cystic fibrosis patients with advanced lung dis…
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CLINICAL_TRIALS trial_result · 2017-05-15Clinical Trial Update: Early Methicillin-resistant Staphylococcus Aureus (MRSA) Therapy in Cystic Fibrosis (CF) [Phase 2]
A Phase 2 trial evaluating early methicillin-resistant Staphylococcus aureus therapy in cystic fibrosis was terminated, with results posted …
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CLINICAL_TRIALS trial_result · 2017-05-12Clinical Trial Update: Rollover Study of Ivacaftor in Subjects With Cystic Fibrosis and a Non G551D CFTR Mutation [Phase 3]
Phase 3 rollover study evaluating ivacaftor in cystic fibrosis patients with CFTR mutations other than G551D; study completed and results po…
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CLINICAL_TRIALS trial_result · 2017-05-12Clinical Trial Update: A Phase 3 Rollover Study of Lumacaftor in Combination With Ivacaftor in Subjects 12 Years and Older With Cystic Fibrosis [Phase 3]
Phase 3 rollover trial evaluating lumacaftor in combination with ivacaftor in individuals 12 years and older with cystic fibrosis; the study…
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CLINICAL_TRIALS trial_result · 2017-04-26Clinical Trial Update: Eficacy of Long-term Suplementation With Docosahexaenoic Acid in Patients With Cystic Fibrosis [NA]
This clinical trial update reports on the efficacy of long-term docosahexaenoic acid supplementation in patients with cystic fibrosis.
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CLINICAL_TRIALS trial_result · 2017-04-13Clinical Trial Update: Population Pharmacokinetics and Safety of Intravenous Ceftolozane/Tazobactam in Adult Cystic Fibrosis Patients [Phase 4]
Phase 4 trial evaluating population pharmacokinetics and safety of intravenous ceftolozane/tazobactam in adult cystic fibrosis patients, com…
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CLINICAL_TRIALS trial_result · 2017-04-13Clinical Trial Update: A Coaching Intervention to Young Adults With Cystic Fibrosis [NA]
This entry reports the completion of a clinical trial testing a coaching intervention for young adults with cystic fibrosis, conducted in De…
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CLINICAL_TRIALS trial_result · 2017-04-12Clinical Trial Update: Do More, B'More, Live Fit [NA]
This ClinicalTrials.gov update indicates that the Johns Hopkins University study 'Do More, B'More, Live Fit' (NCT03109912) focusing on cysti…
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CLINICAL_TRIALS trial_result · 2017-04-06Clinical Trial Update: Costimulatory Molecules as Biomarkers in Cystic Fibrosis
A clinical trial evaluating costimulatory molecules as biomarkers in cystic fibrosis has completed under the sponsorship of Oregon Health an…
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CLINICAL_TRIALS trial_result · 2017-04-04Clinical Trial Update: Viral Pathogenesis of Early Cystic Fibrosis Lung Disease
A completed clinical trial update from Indiana University School of Medicine examining viral pathogenesis in early cystic fibrosis lung dise…
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CLINICAL_TRIALS trial_result · 2017-03-30Clinical Trial Update: Doxycycline Effects on Inflammation in Cystic Fibrosis [Phase 4]
A Phase 4 clinical trial evaluating doxycycline's effect on inflammation in cystic fibrosis has completed.
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CLINICAL_TRIALS trial_result · 2017-03-29Clinical Trial Update: Cystic Fibrosis (CF) Leukocyte Genes as Biomarkers for Novel Therapies
A completed clinical trial/update examining leukocyte gene expression as biomarkers to guide development of novel therapies for cystic fibro…
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CLINICAL_TRIALS trial_result · 2017-03-29Clinical Trial Update: Tobramycin Inhalation Powder (TIP) Administered Once Daily Continuously Versus TIP Administered BID in 28 Day on / 28 Day Off Cycles [Phase 4]
This Phase 4 trial compares once-daily continuous Tobramycin Inhalation Powder to twice-daily dosing in cystic fibrosis. The study was termi…
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CLINICAL_TRIALS trial_result · 2017-03-24Clinical Trial Update: IL-17 Neutrophils in CF Lung Inflammation
A completed clinical trial evaluated IL-17 driven neutrophil activity in cystic fibrosis lung inflammation, with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-03-23Clinical Trial Update: Treatment of Aspergillus Fumigatus (a Fungal Infection) in Patients With Cystic Fibrosis [Phase 4]
A Phase 4 clinical trial evaluating treatment for Aspergillus fumigatus infection in cystic fibrosis patients has completed, with results po…
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CLINICAL_TRIALS trial_result · 2017-03-22Clinical Trial Update: Non Invasive Ventilation for Acute Exacerbations in Adult CF [NA]
A clinical trial evaluating non-invasive ventilation for acute exacerbations in adults with cystic fibrosis, with unknown status.
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CLINICAL_TRIALS trial_result · 2017-03-06Clinical Trial Update: Trial of Doxycycline to Reduce Sputum MMP-9 Activity in Adult Cystic Fibrosis (CF) Patients [NA]
A completed clinical trial studied doxycycline to reduce sputum MMP-9 activity in adults with cystic fibrosis. Results have been posted.
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CLINICAL_TRIALS trial_result · 2017-02-27Clinical Trial Update: Biodistribution of Neutrophile Proteases in the Sputum of Patients Affected by Cystic Fibrosis
A completed clinical trial update examining how neutrophil proteases are distributed in the sputum of patients with cystic fibrosis.
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CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: Inhaled Molgramostim (rhGM-CSF) in Healthy Adult Subjects [Phase 1]
Phase 1 trial of inhaled molgramostim (rhGM-CSF) in healthy adults has completed, evaluating safety and tolerability for potential pulmonary…
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CLINICAL_TRIALS trial_result · 2017-02-15Clinical Trial Update: Effect of Sulforaphane in Broccoli Sprouts on Nrf2 Activation [NA]
A completed clinical trial evaluating whether sulforaphane from broccoli sprouts activates the Nrf2 pathway in people with cystic fibrosis; …
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CLINICAL_TRIALS trial_result · 2017-02-15Clinical Trial Update: Nasal Epithelial Cells/Blood Lymphocyte Markers for Cystic Fibrosis (CF)/CF Pulmonary Exacerbations
This completed clinical trial examined nasal epithelial cell and blood lymphocyte biomarkers in cystic fibrosis and CF pulmonary_exacerbatio…
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CLINICAL_TRIALS trial_result · 2017-02-01Clinical Trial Update: Roll-Over Study of Ivacaftor in Cystic Fibrosis Pediatric Subjects With a CF Transmembrane Conductance Regulator Gene (CFTR) Gating Mutation [Phase 3]
This is a Phase 3 roll-over study of ivacaftor in pediatric cystic fibrosis patients with CFTR gating mutations, with results posted in 2017…
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CLINICAL_TRIALS trial_result · 2017-01-31Clinical Trial Update: MAD Study Evaluating the Safety, Tolerability, and Pharmacokinetics of Cavosonstat (N91115) in Healthy Subjects (SNO-9) [Phase 1]
A Phase 1 MAD study of Cavosonstat (N91115) to assess safety, tolerability, and pharmacokinetics in healthy subjects has been completed; cys…