Cystic Fibrosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-11-27Clinical Trial Update: Assessment of Cystic Fibrosis Lung Involvement With UTE Pulse Sequences [NA]
This report notes the completion of a clinical trial assessing cystic fibrosis lung involvement using ultrashort echo time (UTE) MRI pulse s…
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CLINICAL_TRIALS trial_result · 2017-11-21Clinical Trial Update: A Study to Evaluate GLPG2222 in Ivacaftor-treated Subjects With Cystic Fibrosis [Phase 2]
A Phase 2 study evaluated GLPG2222 in cystic fibrosis patients who are already treated with ivacaftor.
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: 28 Day Repeat Dose in Cystic Fibrosis Patients [Phase 2]
This update notes the completion of a Phase 2 trial evaluating a 28-day repeat-dose regimen in cystic fibrosis patients and indicates that r…
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CLINICAL_TRIALS trial_result · 2017-11-14Clinical Trial Update: Combined Dry Powder Tobramycin and Nebulized Colistin Inhalation in CF Patients [Phase 3]
Phase 3 trial testing a combination of dry powder tobramycin and nebulized colistin inhalation in cystic fibrosis with pulmonary manifestati…
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CLINICAL_TRIALS trial_result · 2017-11-07Clinical Trial Update: A Study to Investigate Safety, Tolerability and Pharmacokinetics of Single and Repeat Doses of CHF6333 in Healthy Subjects [Phase 1]
A Phase 1 study evaluating the safety, tolerability and pharmacokinetics of single and repeat doses of CHF6333 in healthy subjects has compl…
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CLINICAL_TRIALS trial_result · 2017-11-01Clinical Trial Update: Study to Evaluate Lumacaftor and Ivacaftor Combination Therapy in Subjects 12 Years and Older With Advanced Lung Disease [Phase 3]
Results from a Phase 3 trial evaluating the lumacaftor/ivacaftor combination in cystic fibrosis patients aged 12 and older with advanced lun…
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CLINICAL_TRIALS trial_result · 2017-10-26Clinical Trial Update: Preventive Inhalation of Hypertonic Saline in Infants With Cystic Fibrosis [Phase 2]
Phase 2 trial evaluating preventive inhalation of hypertonic saline in infants with cystic fibrosis has completed.
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CLINICAL_TRIALS trial_result · 2017-10-23Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Lumacaftor in Combination With Ivacaftor in Subjects With CF, Homozygous for the F508del-CFTR Mutation [Phase 3]
A Phase 3 trial evaluated the efficacy and safety of lumacaftor in combination with ivacaftor in cystic fibrosis patients homozygous for the…
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CLINICAL_TRIALS trial_result · 2017-10-23Clinical Trial Update: Early Intervention in Cystic Fibrosis Exacerbation [NA]
A Johns Hopkins University clinical trial on early intervention during cystic fibrosis exacerbations has completed and posted results (2017-…
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CLINICAL_TRIALS trial_result · 2017-09-25Clinical Trial Update: Imaging Airway Liquid Absorption in Cystic Fibrosis [NA]
Clinical trial on imaging airway liquid absorption in cystic fibrosis has completed with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-09-01Clinical Trial Update: Efficacy of Nasal Irrigation With Respimer® Netiflow® vs Saline Among Patients With Cystic Fibrosis and Chronic Rhinosinusitis [NA]
This clinical trial update compares nasal irrigation with Respimer Netiflow to saline in patients with cystic fibrosis and chronic rhinosinu…
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CLINICAL_TRIALS trial_result · 2017-08-23Clinical Trial Update: Using MRI to Observe Lung Changes in Infants With CF Compared to Infants Without CF
This completed clinical trial used MRI to observe and compare lung changes in infants with cystic fibrosis to those without the condition.
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CLINICAL_TRIALS trial_result · 2017-08-02Clinical Trial Update: The Addition of Non-Invasive Ventilation To Airway Clearance Techniques In Adults With Cystic Fibrosis [NA]
A clinical trial update indicates that the study evaluating adding non-invasive ventilation to airway clearance techniques in adults with cy…
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CLINICAL_TRIALS trial_result · 2017-07-28Clinical Trial Update: Pilot Mouthwash Study of Pioglitazone and Simvastatin in Healthy Volunteers [NA]
Pilot mouthwash study of pioglitazone and simvastatin in healthy volunteers has completed; results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-07-25Clinical Trial Update: A Study of Lung Clearance After Hypertonic Saline Delivery Using the tPAD Device [Phase 1]
Phase 1 clinical trial evaluating lung clearance after hypertonic saline delivery using the tPAD device in cystic fibrosis; the study has co…
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CLINICAL_TRIALS trial_result · 2017-07-25Clinical Trial Update: Assessing Mucociliary Clearance and Airway Liquid Volume in the CF Airway [NA]
A completed clinical trial conducted by the University of Pittsburgh evaluated mucociliary clearance and airway liquid volume in people with…
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CLINICAL_TRIALS trial_result · 2017-07-19Clinical Trial Update: Energy Balance and Weight Gain With Ivacaftor Treatment
A completed clinical trial update examining energy balance and weight gain in cystic fibrosis patients treated with ivacaftor.
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CLINICAL_TRIALS trial_result · 2017-07-19Clinical Trial Update: Safety, Tolerability, Pharmacokinetics, and Preliminary Pharmacodynamics of QBW251 in Healthy Subjects and Cystic Fibrosis Patients [Phase 1, Phase 2]
Phase 1/2 trial evaluating safety, tolerability, PK, and preliminary pharmacodynamics of QBW251 in healthy subjects and cystic fibrosis pati…
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CLINICAL_TRIALS trial_result · 2017-07-13Clinical Trial Update: Vitamin D for Enhancing the Immune System in Cystic Fibrosis (DISC Study) [Phase 3]
A Phase 3 study evaluating vitamin D to enhance immune function in cystic fibrosis has completed.
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CLINICAL_TRIALS trial_result · 2017-07-06Clinical Trial Update: Efficacy Study of IgY (Antibody Against Pseudomonas) in Cystic Fibrosis Patients [Phase 3]
A Phase 3 efficacy study evaluating IgY antibody against Pseudomonas in cystic fibrosis patients has completed.
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CLINICAL_TRIALS trial_result · 2017-07-05Clinical Trial Update: High Flow Nasal Oxygen for Children With Cystic Fibrosis Presenting With Respiratory Failure - a Randomized Controlled Study [NA]
A randomized controlled trial evaluating high-flow nasal oxygen in children with cystic fibrosis and respiratory failure was terminated; no …
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CLINICAL_TRIALS trial_result · 2017-06-27Clinical Trial Update: Increased Vitamin D Reduces Pulmonary Exacerbations in CF
A completed clinical trial indicates that increasing vitamin D supplementation reduces pulmonary exacerbations in patients with cystic fibro…
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CLINICAL_TRIALS trial_result · 2017-06-22Clinical Trial Update: Using Remote Telemonitoring to Detect Early Decline in Lung Function & Streamline Clinics in Adults With Cystic Fibrosis [NA]
A completed clinical trial evaluated the use of remote telemonitoring to detect early decline in lung function and streamline clinic visits …
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CLINICAL_TRIALS trial_result · 2017-06-20Clinical Trial Update: Lung Clearance Index (LCI) in Pediatric Patients With Obstructive Lung Disease [NA]
A pediatric trial evaluating Lung Clearance Index in obstructive lung disease has been terminated; the update does not include results but l…
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: Vitamin D and Microbiota in Cystic Fibrosis [NA]
A completed clinical trial studied the relationship between vitamin D status and gut microbiota in cystic fibrosis patients.