Cystic Fibrosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-04-19Clinical Trial Update: A Phase IIb Study of OligoG in Subjects With Cystic Fibrosis [Phase 2]
The document notes the Phase IIb trial of OligoG in subjects with cystic fibrosis has completed status (COMPLETED) according to ClinicalTria…
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CLINICAL_TRIALS trial_result · 2018-04-17Clinical Trial Update: Behavioral & Nutritional Treatment to Help CF Preschoolers Grow [NA]
This completed ClinicalTrials.gov study evaluated a behavioral and nutritional program to support growth in preschool children with cystic f…
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CLINICAL_TRIALS trial_result · 2018-04-17Clinical Trial Update: Evaluation of an Airway Clearance System [NA]
A completed clinical trial evaluated an airway clearance system for cystic fibrosis.
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CLINICAL_TRIALS trial_result · 2018-04-13Clinical Trial Update: Study of VX-661 Alone and in Combination With Ivacaftor in Subjects Homozygous or Heterozygous to the F508del-Cystic Fibrosis Transmembrane Conductance Regulator(CFTR) Mutation [Phase 2]
Phase 2 study assessing VX-661 (tezacaftor) alone and in combination with ivacaftor in people with the F508del CFTR mutation; trial complete…
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CLINICAL_TRIALS trial_result · 2018-04-13Clinical Trial Update: Study to Evaluate Safety and Efficacy of VX-661 in Combination With Ivacaftor in Subjects With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation With an Open-Label Expansion [Phase 2]
Phase 2 study evaluating safety and efficacy of VX-661 in combination with ivacaftor in cystic fibrosis patients homozygous for the F508del-…
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CLINICAL_TRIALS trial_result · 2018-04-12Clinical Trial Update: A Study to Evaluate Safety, PK and PD of FDL169 in Cystic Fibrosis Subjects [Phase 1]
A Phase 1 study evaluating safety, pharmacokinetics (PK) and pharmacodynamics (PD) of FDL169 in cystic fibrosis subjects has completed.
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CLINICAL_TRIALS trial_result · 2018-04-11Clinical Trial Update: HFN Versus NIV in Cystic Fibrosis. The HIFEN Study [NA]
The HIFEN Study is a completed clinical trial comparing high-flow nasal oxygen therapy (HFN) versus non-invasive ventilation (NIV) in patien…
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CLINICAL_TRIALS trial_result · 2018-04-03Clinical Trial Update: A Study Evaluating Safety and Pharmacokinetics of VX-440 in Combination With Tezacaftor/Ivacaftor in Healthy Adult Subjects [Phase 1]
Phase 1 study assessing safety and pharmacokinetics of VX-440 in combination with Tezacaftor/Ivacaftor in healthy adults has completed.
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CLINICAL_TRIALS trial_result · 2018-03-29Clinical Trial Update: Early Signs of Efficacy Study With Riociguat in Adult Homozygous Delta F508 Cystic Fibrosis Patients [Phase 2]
Phase 2 trial update of riociguat in adult homozygous Delta F508 cystic fibrosis patients was terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2018-03-29Clinical Trial Update: Open-label Vitamin D Trial for Patients With Cystic Fibrosis and Allergic Bronchopulmonary Aspergillosis [NA]
This update notes the completion of an open-label vitamin D trial in patients with cystic fibrosis and allergic bronchopulmonary aspergillos…
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CLINICAL_TRIALS trial_result · 2018-03-19Clinical Trial Update: Pharmacokinetics of GLPG2737 in Male Subjects With Cystic Fibrosis [Phase 1]
Phase 1 pharmacokinetic study of GLPG2737 in male subjects with cystic fibrosis has completed.
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CLINICAL_TRIALS trial_result · 2018-03-14Clinical Trial Update: Increased Gluconeogenesis is One Cause of Cystic Fibrosis Related Diabetes (CFRD) [NA]
A completed clinical trial identified increased gluconeogenesis as one of the causes of cystic fibrosis-related diabetes (CFRD).
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CLINICAL_TRIALS trial_result · 2018-03-13Clinical Trial Update: Biomarkers of Iron Homeostasis and Responses to Cystic Fibrosis Pulmonary Exacerbation (CFPE) Treatment
This completed clinical trial update investigates biomarkers of iron homeostasis and responses to treatment during pulmonary exacerbations i…
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CLINICAL_TRIALS trial_result · 2018-03-13Clinical Trial Update: Cystic Fibrosis- Children and Adults Tai Chi Study [NA]
The clinical trial evaluating Tai Chi as an intervention for cystic fibrosis in children and adults has completed.
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CLINICAL_TRIALS trial_result · 2018-03-12Clinical Trial Update: Evaluation of Inhaled Antibiotics on Bacterial Diversity and Richness in the Cystic Fibrosis Lung
A clinical trial evaluating inhaled antibiotics for their effect on bacterial diversity and richness in the lungs of people with cystic fibr…
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CLINICAL_TRIALS trial_result · 2018-03-08Clinical Trial Update: RESULT: Reliable, Emergent Solution Using Liprotamase Treatment [Phase 3]
Phase 3 trial update on Liprotamase for exocrine pancreatic insufficiency, including use in cystic fibrosis.
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CLINICAL_TRIALS trial_result · 2018-03-07Clinical Trial Update: Use of Formula Fortified With DHA in Infants With Cystic Fibrosis [NA]
A completed clinical trial evaluated an infant formula fortified with DHA for infants with cystic fibrosis.
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CLINICAL_TRIALS trial_result · 2018-02-26Clinical Trial Update: Quantitative Computed Tomodensitometry in Patients With Cystic Fibrosis [NA]
Clinical trial update describing the use of quantitative computed tomography in patients with cystic fibrosis.
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CLINICAL_TRIALS trial_result · 2018-02-23Clinical Trial Update: Safety and Efficacy of Pioglitazone as an Anti-inflammatory for the Treatment of Cystic Fibrosis (CF) Lung Disease [NA]
This clinical trial update evaluates pioglitazone as an anti-inflammatory treatment for cystic fibrosis lung disease. The trial is completed…
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CLINICAL_TRIALS trial_result · 2018-02-09Clinical Trial Update: Safety, Tolerability, Pharmacokinetics, and Efficacy of JBT-101 (Lenabasum) in Cystic Fibrosis [Phase 2]
Phase 2 study evaluating safety, tolerability, pharmacokinetics, and efficacy of lenabasum (JBT-101) in cystic fibrosis; results were posted…
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CLINICAL_TRIALS trial_result · 2018-02-05Clinical Trial Update: Absorptive Clearance After Inhaled Osmotics in Cystic Fibrosis [Phase 1]
Phase 1 trial update on absorptive clearance after inhaled osmotics in cystic fibrosis; study completed with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-01-10Clinical Trial Update: Cystic Fibrosis and Endothelial Function: At Rest and During Exercise [Phase 2]
Phase 2 clinical trial on cystic fibrosis evaluating endothelial function at rest and during exercise; study completed with results posted i…
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CLINICAL_TRIALS trial_result · 2017-12-13Clinical Trial Update: PTC124 for the Treatment of Cystic Fibrosis [Phase 2]
PTC Therapeutics reports the Phase 2 trial of PTC124 (ataluren) for cystic fibrosis has completed.
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CLINICAL_TRIALS trial_result · 2017-11-30Clinical Trial Update: Non-respiratory Comorbidities Observed in Pulmonary French Transplant Patients With Cystic Fibrosis
A completed clinical trial update describes non-respiratory comorbidities observed in French lung transplant recipients with cystic fibrosis…
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CLINICAL_TRIALS trial_result · 2017-11-30Clinical Trial Update: Efficacy and Safety Study of EGCG/Tocotrienol in 18 Patients With Splicing-mutation-mediated Cystic Fibrosis (CF) [NA]
A completed clinical trial evaluated the efficacy and safety of a combined EGCG and tocotrienol regimen in 18 patients with splicing-mutatio…