Cystic Fibrosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-02-06Clinical Trial Update: Dose Escalation Study of QR-010 in Homozygous ΔF508 Cystic Fibrosis Patients [Phase 1, Phase 2]
A dose-escalation Phase 1/2 trial of QR-010 in adults with homozygous ΔF508 cystic fibrosis has completed. Results were posted in February 2…
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CLINICAL_TRIALS trial_result · 2019-01-31Clinical Trial Update: Kinetics of YKL-40 Protein in Serum of Cystic Fibrosis Patients
This completed clinical trial evaluated the kinetics of the YKL-40 protein in the serum of cystic fibrosis patients.
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CLINICAL_TRIALS trial_result · 2019-01-30Clinical Trial Update: Impact of Art Therapy on Anxiety Identified During Hospitalizations Among Children With Cystic Fibrosis Aged 8 to 13
A completed clinical trial assessed whether art therapy reduces anxiety during hospitalizations among children aged 8 to 13 with cystic fibr…
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CLINICAL_TRIALS trial_result · 2019-01-30Clinical Trial Update: Perceived Impact of Art Therapy in Patients With Cystic Fibrosis and in Professional Interdisciplinary Teams Taking Care of Them.
This clinical trial update assesses the perceived impact of art therapy on patients with cystic fibrosis and on the professional interdiscip…
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CLINICAL_TRIALS trial_result · 2019-01-08Clinical Trial Update: A Phase 3 Study of Tezacaftor (VX-661) in Combination With Ivacaftor (VX-770) in Subjects Aged 12 Years and Older With Cystic Fibrosis (CF), Who Have One F508del-CFTR Mutation and a Second Mutation That Has Been Demonstrated to be Clinically Responsive to Ivacaftor [Phase 3]
Phase 3 study evaluating tezacaftor in combination with ivacaftor in CF patients aged 12+ with one F508del-CFTR mutation and a responsive se…
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CLINICAL_TRIALS trial_result · 2018-11-27Clinical Trial Update: Steady-state Pharmacokinetics of Ceftazidime/Avibactam in Cystic Fibrosis [Phase 4]
Phase 4 study reporting steady-state pharmacokinetics of ceftazidime/avibactam in patients with cystic fibrosis; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-11-20Clinical Trial Update: Persistent Methicillin Resistant Staphylococcus Aureus Eradication Protocol (PMEP) [Phase 2]
A Phase 2 clinical trial update on the Persistent Methicillin Resistant Staphylococcus Aureus Eradication Protocol (PMEP) for cystic fibrosi…
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CLINICAL_TRIALS trial_result · 2018-11-19Clinical Trial Update: A Study to Evaluate Efficacy and Safety of Ivacaftor in Subjects With Cystic Fibrosis Aged 3 Through 5 Years Who Have a Specified CFTR Gating Mutation [Phase 3]
A Phase 3 trial evaluating ivacaftor in children aged 3-5 with a CFTR gating mutation in cystic fibrosis has been terminated with results po…
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CLINICAL_TRIALS trial_result · 2018-11-16Clinical Trial Update: A Study to Evaluate Multiple Doses of GLPG2222 in Adult Subjects With Cystic Fibrosis [Phase 2]
Phase 2 trial update for GLPG2222 in adults with cystic fibrosis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-11-05Clinical Trial Update: To Assess the Safety, Tolerability and Pharmacokinetics of AZD5634 Following Inhaled and Intravenous (IV)Dose Administration [Phase 1]
Phase 1 clinical trial assessing safety, tolerability, and pharmacokinetics of AZD5634 via inhaled and IV administration in cystic fibrosis …
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CLINICAL_TRIALS trial_result · 2018-10-30Clinical Trial Update: Safety and Pharmacokinetic Study of Lumacaftor/Ivacaftor in Subjects Aged 2 Through 5 Years With Cystic Fibrosis, Homozygous for F508del [Phase 3]
Clinical trial update reporting safety and pharmacokinetics of Lumacaftor/Ivacaftor in young children (2-5 years) with cystic fibrosis homoz…
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CLINICAL_TRIALS trial_result · 2018-10-26Clinical Trial Update: Clinical Effects of Exercise Program Added to Pulmonary Rehabilitation in Patients With Cystic Fibrosis [NA]
A completed clinical trial evaluating the effects of adding an exercise program to pulmonary rehabilitation in patients with cystic fibrosis…
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CLINICAL_TRIALS trial_result · 2018-10-09Clinical Trial Update: Evaluation of Lung Clearance Index in Cystic Fibrosis (CF) Patients, Infected With P.Aeruginosa [Phase 4]
Phase 4 clinical trial evaluating lung clearance index in cystic fibrosis patients with chronic Pseudomonas aeruginosa infection; the study …
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CLINICAL_TRIALS trial_result · 2018-10-05Clinical Trial Update: 18FDG-PET Imaging to Detect Changes in Airways Inflammation in Cystic Fibrosis Patients [Phase 3]
Phase 3 trial evaluating 18FDG-PET imaging to detect changes in airway inflammation in cystic fibrosis patients.
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CLINICAL_TRIALS trial_result · 2018-10-02Clinical Trial Update: Lumacaftor/Ivacaftor Combination Therapy in Subjects With CF Who Have an A455E CFTR Mutation [Phase 2]
Phase 2 trial evaluating lumacaftor/ivacaftor in cystic fibrosis patients with the A455E CFTR mutation; study completed with results posted …
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CLINICAL_TRIALS trial_result · 2018-09-27Clinical Trial Update: A Pilot Study to Evaluate the Use of Smart Adherence Technology to Measure Lumacaftor/Ivacaftor Adherence in CF Subjects Homozygous for the F508del CFTR Mutation [Phase 4]
A Phase 4 pilot study evaluating smart adherence technology to measure lumacaftor/ivacaftor adherence in cystic fibrosis patients homozygous…
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CLINICAL_TRIALS trial_result · 2018-09-06Clinical Trial Update: Effect of High Frequency Chest Wall Oscillation Vests on Spirometry Measurements [NA]
Clinical trial completion update evaluating high frequency chest wall oscillation vests on spirometry in cystic fibrosis and bronchiectasis;…
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CLINICAL_TRIALS trial_result · 2018-09-04Clinical Trial Update: Inhaled Xylitol Versus Saline in Stable Subjects With Cystic Fibrosis [Phase 1, Phase 2]
Phase 1/2 trial comparing inhaled xylitol to saline in stable cystic fibrosis patients; results posted after completion.
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CLINICAL_TRIALS trial_result · 2018-08-14Clinical Trial Update: SOLUTION: Study of Oral Liprotamase Unit-Matched Therapy Of Non-Porcine Origin in Patients With Cystic Fibrosis [Phase 3]
A Phase 3 trial update for SOLUTION study of an oral liprotamase unit-matched therapy in non-porcine origin for cystic fibrosis with exocrin…
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CLINICAL_TRIALS trial_result · 2018-08-13Clinical Trial Update: Macrolide Antibiotic Therapy for Patients With Cystic Fibrosis [Phase 2]
Phase 2 trial update on macrolide antibiotic therapy for patients with cystic fibrosis.
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CLINICAL_TRIALS trial_result · 2018-08-06Clinical Trial Update: An Efficacy and Safety Study of Ivacaftor in Patients With Cystic Fibrosis and Two Splicing Mutations [Phase 3]
Phase 3 trial evaluating Ivacaftor in cystic fibrosis patients with two splicing mutations has completed with posted results.
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CLINICAL_TRIALS trial_result · 2018-08-06Clinical Trial Update: Effects of Mycophenolate Mofetil in Cystic Fibrosis Lung Transplant Patients
A completed clinical trial evaluating the effects of mycophenolate mofetil in lung transplant recipients with cystic fibrosis; results poste…
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CLINICAL_TRIALS trial_result · 2018-08-02Clinical Trial Update: Effect of Azithromycin on Fatty Acids in CF [Phase 4]
Phase 4 trial exploring the effect of azithromycin on fatty acids in cystic fibrosis patients.
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CLINICAL_TRIALS trial_result · 2018-07-27Clinical Trial Update: A Phase 2 Study to Evaluate Effects of VX-661/Ivacaftor on Lung and Extrapulmonary Systems in Subjects With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation [Phase 2]
Phase 2 trial evaluating VX-661/Ivacaftor in cystic fibrosis patients homozygous for F508del-CFTR; study completed with results posted in 20…
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CLINICAL_TRIALS trial_result · 2018-07-24Clinical Trial Update: FDG-PET Imaging in Young Cystic Fibrosis Patients [NA]
A completed clinical trial update reports results from FDG-PET imaging in young patients with cystic fibrosis.