Cystic Fibrosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-05-14Clinical Trial Update: Study of Ataluren (PTC124™) in Cystic Fibrosis [Phase 3]
Phase 3 trial update for ataluren (PTC124) in cystic fibrosis completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-05-14Clinical Trial Update: Study of Ataluren in Nonsense Mutation Cystic Fibrosis (ACT CF) [Phase 3]
Phase 3 trial update for ataluren in nonsense mutation cystic fibrosis has completed with results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-04-24Clinical Trial Update: Blood Flow and Vascular Function in Cystic Fibrosis [Phase 2]
Phase 2 clinical trial assessing blood flow and vascular function in cystic fibrosis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-04-22Clinical Trial Update: Study Designed to Assess the Safety, Tolerability and PK of PTI-808 in Healthy Volunteers and in Adults With Cystic Fibrosis [Phase 1, Phase 2]
Clinical trial update for PTI-808 focusing on safety, tolerability, and pharmacokinetics in healthy volunteers and adults with cystic fibros…
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CLINICAL_TRIALS trial_result · 2020-04-15Clinical Trial Update: Extension Study of Ataluren in Participants With Nonsense Mutation Cystic Fibrosis [Phase 3]
Extension study of ataluren in nonsense mutation cystic fibrosis participants has terminated; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-04-08Clinical Trial Update: Functional Respiratory Imaging and Orkambi in CF [Phase 4]
Phase 4 trial update investigating Functional Respiratory Imaging and Orkambi in cystic fibrosis has been terminated.
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CLINICAL_TRIALS trial_result · 2020-04-06Clinical Trial Update: Safety, Tolerability, and Pharmacokinetics of PTI-808, PTI-801, and PTI-428 Combination Therapy in Subjects With Cystic Fibrosis [Phase 1, Phase 2]
Phase 1/2 study assessing safety, tolerability, and pharmacokinetics of PTI-808, PTI-801, and PTI-428 combination in cystic fibrosis patient…
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CLINICAL_TRIALS trial_result · 2020-03-27Clinical Trial Update: Pharmacokinetics of Linezolid in Children With Cystic Fibrosis [Phase 2]
Phase 2 trial update on the pharmacokinetics of linezolid in children with cystic fibrosis.
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CLINICAL_TRIALS trial_result · 2020-03-26Clinical Trial Update: PTC Study to Evaluate Ataluren in Combination With Ivacaftor [Phase 4]
A Phase 4 clinical trial evaluating ataluren in combination with ivacaftor for cystic fibrosis has been completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-03-25Clinical Trial Update: Study of Ataluren (PTC124) in Cystic Fibrosis [Phase 3]
Phase 3 study of ataluren (PTC124) in cystic fibrosis was terminated; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-03-13Clinical Trial Update: A Phase 3 Study of VX-659 Combination Therapy in Subjects With Cystic Fibrosis Heterozygous for the F508del Mutation and a Minimal Function Mutation (F/MF) [Phase 3]
Phase 3 study of VX-659 combination therapy in CF patients with F508del and minimal function mutation completed; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-03-06Clinical Trial Update: A Study of Ataluren in Pediatric Participants With Cystic Fibrosis [Phase 2]
Phase 2 trial update of ataluren in pediatric cystic fibrosis participants completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-02-27Clinical Trial Update: Study Assessing PTI-428 Safety, Tolerability, Pharmacokinetics and Effect in Subjects With Cystic Fibrosis [Phase 2]
Phase 2 trial update for PTI-428 (proteostasis therapeutics) assessing safety, tolerability, pharmacokinetics, and effect in cystic fibrosis…
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CLINICAL_TRIALS trial_result · 2020-02-11Clinical Trial Update: A Study to Evaluate Efficacy and Safety of TEZ/IVA in Subjects Aged 6 Through 11 Years With Cystic Fibrosis [Phase 3]
Phase 3 study evaluating TEZ/IVA in children aged 6-11 with cystic fibrosis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-02-05Clinical Trial Update: Evaluation of VX-659/TEZ/IVA in Cystic Fibrosis Subjects 6 Through 11 Years of Age [Phase 3]
Phase 3 trial evaluating VX-659/TEZ/IVA in children aged 6-11 with cystic fibrosis was terminated; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-01-27Clinical Trial Update: A Study of VX-445 Combination Therapy in CF Subjects Homozygous for F508del (F/F) [Phase 3]
Phase 3 study of VX-445 combination therapy in cystic fibrosis patients with F508del/F508del has completed; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-01-18Clinical Trial Update: Single Dose of pGM169/GL67A in CF Patients [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial evaluating a single dose of pGM169/GL67A in cystic fibrosis patients; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-01-13Clinical Trial Update: Efficacy and Safety Study of AeroVanc for the Treatment of Persistent MRSA Lung Infection in Cystic Fibrosis Patients [Phase 2]
Phase 2 trial update on AeroVanc for persistent MRSA lung infection in cystic fibrosis patients reports efficacy and safety findings.
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CLINICAL_TRIALS trial_result · 2020-01-09Clinical Trial Update: The Role of Oral Glutathione on Growth Parameters in Children With Cystic Fibrosis [Phase 2]
Phase 2 trial investigating the effect of oral glutathione on growth parameters in children with cystic fibrosis has completed with results …
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CLINICAL_TRIALS trial_result · 2020-01-06Clinical Trial Update: A Study to Evaluate Efficacy of Ivacaftor in Subjects With Cystic Fibrosis Who Have a 3849 + 10KB C→T or D1152H CFTR Mutation [Phase 3]
A Phase 3 trial evaluating ivacaftor for cystic fibrosis patients with specific CFTR mutations (3849+10kb C→T or D1152H) has completed with …
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CLINICAL_TRIALS trial_result · 2019-12-30Clinical Trial Update: An Efficacy and Safety Study of SPX-101 Inhalation Solution in Subjects With Cystic Fibrosis [Phase 2]
Phase 2 trial update for SPX-101 inhalation solution in cystic fibrosis completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-12-05Clinical Trial Update: A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of VX-661/Ivacaftor in Pediatric Subjects With Cystic Fibrosis (CF) [Phase 3]
Phase 3 trial update assessing pharmacokinetics, safety, and tolerability of VX-661/ivacaftor in pediatric cystic fibrosis patients has comp…
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CLINICAL_TRIALS trial_result · 2019-11-27Clinical Trial Update: BI 443651 Multiple Rising Dose in Healthy Volunteers Followed by a Cross-over in CF Subjects [Phase 1]
Phase 1 trial of BI 443651 in healthy volunteers followed by crossover in cystic fibrosis subjects completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-11-13Clinical Trial Update: Effect of HFCWO Vests on Spirometry Measurements [NA]
Completed clinical trial assessing the effect of high-frequency chest wall oscillation (HFCWO) vests on spirometry measurements in cystic fi…
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CLINICAL_TRIALS trial_result · 2019-10-29Clinical Trial Update: Rollover Study to Evaluate the Safety and Efficacy of Long-term Treatment With Lumacaftor in Combination With Ivacaftor [Phase 3]
A Phase 3 rollover study evaluating long-term safety and efficacy of lumacaftor in combination with ivacaftor for cystic fibrosis has comple…