Cystic Fibrosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-02-11Clinical Trial Update: Improving Treatment of Nontuberculous Mycobacterial Infection in Cystic Fibrosis [NA]
Clinical trial update on improving treatment of nontuberculous mycobacterial infection in cystic fibrosis has completed; results posted in 2…
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CLINICAL_TRIALS trial_result · 2021-02-03Clinical Trial Update: Safety, Efficacy, and Feasibility of High-dose Cholecalciferol in Pediatric Patients With Cystic Fibrosis [Phase 2]
Phase 2 trial updating safety, efficacy, and feasibility of high-dose vitamin D (cholecalciferol) in pediatric cystic fibrosis patients with…
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CLINICAL_TRIALS trial_result · 2021-01-28Clinical Trial Update: A Study Evaluating the Safety of VX-152 Combination Therapy in Adults With Cystic Fibrosis [Phase 2]
Phase 2 trial evaluating safety of VX-152 combination therapy in adults with cystic fibrosis has completed; results posted.
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CLINICAL_TRIALS trial_result · 2021-01-12Clinical Trial Update: Aztreonam Aerosol to Treat Cystic Fibrosis Nasal Disease [Phase 2]
Phase 2 trial update for aztreonam aerosol in cystic fibrosis nasal disease was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2021-01-06Clinical Trial Update: Evaluating High Flow Humidification Therapy in Patients With Cystic Fibrosis [NA]
Clinical trial evaluating high flow humidification therapy in cystic fibrosis patients has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-12-19Clinical Trial Update: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QAU145 in Patients With Cystic Fibrosis [Phase 2]
Phase 2 clinical trial update assessing safety, tolerability, pharmacokinetics, and pharmacodynamics of QAU145 in patients with cystic fibro…
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CLINICAL_TRIALS trial_result · 2020-11-13Clinical Trial Update: Losartan and Inflammation in Cystic Fibrosis [Phase 2]
Phase 2 clinical trial investigating losartan for inflammation in cystic fibrosis; study terminated with results posted.
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CLINICAL_TRIALS trial_result · 2020-11-04Clinical Trial Update: Tobramycin Inhalation Powder (TIP) in Cystic Fibrosis Patients Infected With Burkholderia Cepacia Complex [Phase 1]
Phase 1 trial update for tobramycin inhalation powder in cystic fibrosis patients infected with Burkholderia cepacia complex; study complete…
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CLINICAL_TRIALS trial_result · 2020-10-19Clinical Trial Update: Extension Study of Ataluren (PTC124) in Cystic Fibrosis [Phase 3]
Extension study update for ataluren (PTC124) in cystic fibrosis; Phase 3 completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-10-09Clinical Trial Update: Long Term Administration of Inhaled Mannitol in Cystic Fibrosis [Phase 3]
Phase 3 trial update on long-term inhaled mannitol administration for cystic fibrosis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-09-29Clinical Trial Update: Short Term Effects of Ivacaftor in Non-G551D Cystic Fibrosis Patients [NA]
A completed clinical trial evaluating short-term effects of ivacaftor in cystic fibrosis patients without the G551D mutation.
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CLINICAL_TRIALS trial_result · 2020-09-24Clinical Trial Update: Exploratory Study to Evaluate QR-010 in Subjects With Cystic Fibrosis ΔF508 CFTR Mutation [Phase 1]
Phase 1 exploratory study of QR-010 in subjects with cystic fibrosis carrying the ΔF508 CFTR mutation has completed.
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CLINICAL_TRIALS trial_result · 2020-09-03Clinical Trial Update: A Safety and Efficacy Trial of Inhaled Mannitol in Adult Cystic Fibrosis Subjects [Phase 3]
Phase 3 trial evaluating inhaled mannitol in adult cystic fibrosis patients has completed with posted results.
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CLINICAL_TRIALS trial_result · 2020-08-28Clinical Trial Update: A Study Evaluating the Safety and Efficacy of VX-440 Combination Therapy in Subjects With Cystic Fibrosis [Phase 2]
Phase 2 trial evaluating VX-440 combination therapy in cystic fibrosis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-08-26Clinical Trial Update: Study to Evaluate the Safety and Efficacy of CTP-656 in Patients With Cystic Fibrosis With CFTR Gating Mutations [Phase 2]
Phase 2 trial evaluating CTP-656 in cystic fibrosis with CFTR gating mutations was terminated; results posted.
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CLINICAL_TRIALS trial_result · 2020-08-07Clinical Trial Update: A Rollover Safety Study of Lumacaftor/Ivacaftor in Subjects Aged 2 Years and Older With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation [Phase 3]
A Phase 3 rollover safety study evaluating lumacaftor/ivacaftor in cystic fibrosis patients aged 2 years and older with the F508del-CFTR mut…
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CLINICAL_TRIALS trial_result · 2020-07-31Clinical Trial Update: A Single Arm 48-Week Follow-on Safety Study to a Core Study Comparing the Efficacy and Tolerability of Tobrineb®/Actitob®/Bramitob® Versus TOBI® [Phase 3]
A single-arm 48-week safety follow-up study assessing Tobrineb/Actitob/Bramitob against TOBI in cystic fibrosis patients; phase 3 completed.
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CLINICAL_TRIALS trial_result · 2020-07-13Clinical Trial Update: Efficacy and Safety of Tigerase® vs. Pulmozyme® in Patients With Cystic Fibrosis [Phase 3]
Phase 3 trial comparing Tigerase® to Pulmozyme® in cystic fibrosis patients completed.
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CLINICAL_TRIALS trial_result · 2020-07-07Clinical Trial Update: Polyethylene Glycol and Intestinal Inflammation in Cystic Fibrosis [Phase 2]
Phase 2 clinical trial update on polyethylene glycol for intestinal inflammation in cystic fibrosis.
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CLINICAL_TRIALS trial_result · 2020-06-30Clinical Trial Update: Human Factors Study to Validate the User Interface of TOBI Podhaler Using Placebo Capsules [Phase 4]
Phase 4 human factors study assessing the user interface of TOBI Podhaler with placebo capsules; completed with results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-06-16Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of Long Term Treatment With VX-661 in Combination With Ivacaftor in Participants With Cystic Fibrosis Who Have an F508del-CFTR Mutation [Phase 3]
Phase 3 trial evaluating long-term safety and efficacy of VX-661 (Tezacafor? actually VX-661 is a CFTR corrector) with Ivacaftor in CF patie…
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CLINICAL_TRIALS trial_result · 2020-06-11Clinical Trial Update: Safety and Efficacy of Ataluren (PTC124) for Cystic Fibrosis [Phase 2]
Phase 2 clinical trial update on ataluren (PTC124) for cystic fibrosis evaluating safety and efficacy.
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CLINICAL_TRIALS trial_result · 2020-06-02Clinical Trial Update: The Role of Vitamin D3 in Pediatric Bronchiectasis Severity [Phase 2, Phase 3]
Phase 2/3 clinical trial evaluating the role of Vitamin D3 in pediatric bronchiectasis severity, including cystic fibrosis and non-CF bronch…
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CLINICAL_TRIALS trial_result · 2020-05-20Clinical Trial Update: A Two-Part Multicenter Prospective Longitudinal Study of CFTR-dependent Disease Profiling in Cystic Fibrosis (PROSPECT)
A completed multicenter longitudinal study in cystic fibrosis evaluating CFTR-dependent disease profiling; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-05-19Clinical Trial Update: A Phase 3 Study of VX-445 Combination Therapy in Subjects With Cystic Fibrosis Heterozygous for the F508del Mutation and a Minimal Function Mutation (F/MF) [Phase 3]
Phase 3 study of VX-445 combination therapy in cystic fibrosis patients with specific mutations has completed with results posted.